■前庭神经鞘瘤(VS)是一种良性肿瘤,由第八对颅骨的施万细胞发展而来,主要在小脑桥脑角。
我们报告了一例30岁的女性患者,出现左耳痛并伴有耳鸣,其演变的标志是静态小脑综合征和行为障碍的发展,其脑部MRI显示桥脑小脑角的局部进展过程,以牺牲前庭耳蜗神经为代价,赞成VS,由于扁桃体的受累而变得复杂,不幸的是导致了病人的死亡。
■VS,以前被称为听神经瘤,是一种轴外颅内肿瘤,占桥小脑角肿瘤的80%以上,并且在大多数情况下继发于2型神经纤维瘤病(NF2)抑癌基因的失活,通过NF2基因的突变或染色体22q的丢失。在大多数情况下,它是单方面和孤独的,但是在几乎8%的案例中,它与NF2相关联。脑MRI是检测的首选检查,表征,在不需要活检的情况下诊断为VS,主要是在注射钆之前和之后的T1加权序列。治疗主要基于手术或放射外科,根据大小,影响,和治疗团队的专业知识。
■VS仍然是重要的颅内肿瘤实体,在局部入侵的情况下可能会危及生命。
UNASSIGNED: Vestibular schwannoma (VS) is a benign tumor that develops from Schwann cells of the eighth cranial pair, mainly in the cerebellopontine angle.
UNASSIGNED: We report the
case of a 30-year-old female patient who developed left otalgia associated with neglected tinnitus, the evolution of which was marked by the development of a static cerebellar syndrome and a behavioral disorder, whose brain MRI revealed a locally advanced process in the cerebellopontine angle at the expense of the vestibulocochlear nerve, in favor of a VS, complicated by involvement of the tonsils, which unfortunately led to the patient\'s death.
UNASSIGNED: VS, formerly known as acoustic neuroma, is an extra-axial intracranial tumor that accounts for over 80% of pontocerebellar angle tumors, and is secondary in the majority of cases to inactivation of the neurofibromatosis type 2 (NF2) tumor suppressor gene, either by mutation of the NF2 gene or loss of chromosome 22q. In the majority of cases, it is unilateral and solitary, but in almost 8% of cases, it is associated with NF2. Cerebral MRI is the examination of choice for the detection, characterization, and diagnosis of VS without the need for biopsy, mainly with T1-weighted sequences before and after gadolinium injection. Treatment is based essentially on surgery or radiosurgery, depending on the size, impact, and expertise of the treatment team.
UNASSIGNED: VS remains an important intracranial tumor entity, which can be life-threatening in cases of advanced local invasion.