net protein balance

净蛋白质平衡
  • 文章类型: Journal Article
    充足的蛋白质摄入对于维持全身蛋白质质量至关重要。使用不同的方法学方法来证实当前蛋白质建议的证据,人们一直在争论老年人是否需要更多的蛋白质来抵消年龄依赖性的肌肉质量损失,肌肉减少症.因此,这个关键的叙述审查的目的是概述和讨论的方法和评估蛋白质需求的差异,因此,导致目前对健康老年人的蛋白质建议存在争议。通过文献检索,这篇叙述性综述首先总结了粮食及农业组织/世界卫生组织/联合国大学对健康老年人的蛋白质需求和建议的历史发展。此后,我们描述了各种类型的研究(流行病学研究和蛋白质周转动力学测量)和应用的方法学方法,这些方法奠定了基础,并提出了不同的建议,重点是健康的老年人。最后,我们讨论了在未来研究中需要考虑的重要因素,以获得关于蛋白质需求的国际协议的证据,并推荐健康老年人.最后,我们提出了未来的方向,以确定“真正的”蛋白质需求和健康老年人的建议。
    Adequate protein intake is essential for the maintenance of whole-body protein mass. Different methodological approaches are used to substantiate the evidence for the current protein recommendations, and it is continuously debated whether older adults require more protein to counteract the age-dependent loss of muscle mass, sarcopenia. Thus, the purpose of this critical narrative review is to outline and discuss differences in the approaches and methodologies assessing the protein requirements and, hence, resulting in controversies in current protein recommendations for healthy older adults. Through a literature search, this narrative review first summarises the historical development of the Food and Agriculture Organization/World Health Organization/United Nations University setting of protein requirements and recommendations for healthy older adults. Hereafter, we describe the various types of studies (epidemiological studies and protein turnover kinetic measurements) and applied methodological approaches founding the basis and the different recommendations with focus on healthy older adults. Finally, we discuss important factors to be considered in future studies to obtain evidence for international agreement on protein requirements and recommendations for healthy older adults. We conclude by proposing future directions to determine \'true\' protein requirements and recommendations for healthy older adults.
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