临床毒理学研究对于检测和评估可疑麻醉品中毒的严重程度非常有帮助。在某些情况下,最初的临床中毒病例然后在进一步的过程中发展为法医相关的病例(例如,在故意中毒之后,有敲除毒品或打算谋杀,或在与刑事犯罪有关的醉酒情况下)。关于所提供的麻醉药品,解释了在临床和法医案件中对这些物质进行分析检测的细节和问题。使用的信息来自我们自己的考试材料和文献数据的数据。近年来,成瘾物质的范围发生了显着变化。虽然已建立的检测方法可用于酒精和经典滥用药物,可能被滥用的新药(如哌醋甲酯,普瑞巴林)或NPS,GHB,GBL,常规免疫化学方法与GC-MS和HPLC-DAD等色谱方法无法检测到4-BD。因此,需要对进行此类调查的专业实验室的测量设备进行改进,以便能够充分照顾患者并澄清刑事犯罪。为了法律的确定性,这对罪犯来说很重要,在向受害者提供外来物质的情况下,假设它也可以被证明。此外,关于官方公布的麻醉药品在与毒品有关的死亡中的流行率数据的可靠性,在收集所有相关物质时应寻求更大的安全性。
Clinical-toxicological investigations are very helpful for the detection and assessment of the severity of questionable narcotics intoxications. In some cases, an initial
case of clinical poisoning then progresses in the further course to a
case of forensic relevance (for example after deliberate poisoning e.g, with knock-out drugs or with intend to commit murder, or in cases of intoxication in connection with a criminal offense).The specifics and problems of the analytical detection of these substances in clinical and forensic cases are explained with regard to the presented narcotic drugs. The information used comes from data from our own examination material and data from the literature.The spectrum of addictive substances has changed significantly in recent years. While established methods of detection are available for alcohol and classic drugs of abuse, new drugs with potential for abuse (such as methylphenidate, pregabalin) or NPS, GHB, GBL, and 4‑BD cannot be detected by conventional methods of immunochemistry in combination with chromatographic methods such as GC-MS and HPLC-DAD.An improvement in the measurement equipment for specialised laboratories performing such investigations is therefore required in order to be able to adequately care for patients and to clarify criminal offenses. In the interests of legal certainty, it is important for offenders, in the
case of a foreign substance being supplied to a victim, to assume that it can also be proven. In addition, with regard to the reliability of officially stated prevalence data for narcotic drugs in drug-related deaths, greater safety should be sought in the collection of all relevant substances.