背景:孤立的婴儿肌纤维瘤是一种硬的,无痛性皮肤或皮下结节,被定义为一种罕见的软组织肿瘤,通常见于儿童时期。
方法:一名9个月大的女婴在一个月前出现了一个固体肿块。颈部右后三角形内肿块逐渐增大,没有任何局部或全身伴随症状。实验室检查正常。超声检查显示均匀的组织肿块,大小为1.5×3厘米,血液在里面流动。多层CT扫描准确定位孤立的肿瘤。手术切除肿块,在胸锁乳突肌内发现,与邻近组织无任何粘连。肿瘤的组织学检查和免疫组织化学测试证实了婴儿肌纤维瘤。
■IM是儿童最常见的软组织肿瘤之一,主要由肌成纤维细胞组成。90%的IM病例是在两岁之前诊断的。这种肿瘤的可能治疗措施包括保守治疗,手术切除,化疗,放射治疗,和类固醇注射到肿瘤中。经常进行手术切除肿瘤,如果它是单一的并且完全被移除,预后良好,复发率低于10%。
结论:婴儿肌纤维瘤被认为是良性肿瘤,但在某些情况下可能是致命的。每个病例根据数量单独治疗(单中心或多中心),尺寸,location,症状,和内脏受累。在大多数情况下,手术切除仍然是选择的治疗程序。
BACKGROUND: A solitary infantile myofibroma tumor arises as a hard, painless cutaneous or subcutaneous nodule and is defined as an uncommon soft tissue neoplasm that is usually seen in childhood.
METHODS: A nine-month-old female infant presented with a solid mass that appeared one month ago. The mass gradually increased in size within the right posterior triangle of the neck, without any local or systemic accompanying symptoms. Laboratory tests were normal. Ultrasonography revealed a homogeneous tissue mass measuring 1.5 × 3 cm, with blood flow within it. Multislice CT scan accurately localized the isolated tumor. The mass was surgically excised and found within the sternocleidomastoid muscle, without any adhesions to adjacent tissues. Histological examination of the tumor and immunohistochemical tests confirmed infantile myofibroma.
UNASSIGNED: IM is one of the most common soft tissue tumors in children and mainly consists of myofibroblasts. 90 % of IM cases are diagnosed before the age of two years. Possible therapeutic measures for this tumor include conservative management, surgical resection, chemotherapy, radiation therapy, and steroid injections into the tumor. Surgical removal of the tumor is often performed, and if it is single and completely removed, the prognosis is good with a recurrence rate of less than 10 %.
CONCLUSIONS: Infantile myofibroma is considered a benign tumor, but it may be fatal in some cases. Each
case is treated individually according to the number (single or multicentric), size, location, symptoms, and visceral involvement. Surgical resection remains the therapeutic procedure of choice in most cases.