肺是仅次于肝脏的结肠直肠癌(CRC)的第二常见转移部位。与结肠癌相比,直肠癌与更高的肺转移发生率相关。在中国,直肠癌病例的比例约为50%,远高于西方国家(近30%)。然而,目前尚无针对有肺转移的CRC的共识或指南.根据目前的研究报告和专家的临床经验和知识,我们进行了广泛的讨论,并就CRC肺转移的管理达成了共识。该共识提供了详细的诊断和鉴别诊断方法,并为肺转移的多学科治疗(MDT)提供了一般指南。我们还重点介绍了MDT管理同步肺转移和初始异时肺转移的建议。这一共识可能会改善中国结直肠癌肺转移的临床实践,并将鼓励肿瘤学家进行更多的临床试验,以获得有关治疗肺转移的高水平证据。
The lungs are the second most common site of metastasis for colorectal cancer (CRC) after the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to colon cancer. In China, the proportion of rectal cancer cases is around 50%, much higher than that in Western countries (nearly 30%). However, there is no available
consensus or
guideline focusing on CRC with lung metastases. We conducted an extensive discussion and reached a
consensus of management for lung metastases in CRC based on current research reports and the experts\' clinical experiences and knowledge. This
consensus provided detailed approaches of diagnosis and differential diagnosis and provided general
guidelines for multidisciplinary therapy (MDT) of lung metastases. We also focused on recommendations of MDT management of synchronous lung metastases and initial metachronous lung metastases. This
consensus might improve clinical practice of CRC with lung metastases in China and will encourage oncologists to conduct more clinical trials to obtain high-level evidences about managing lung metastases.