mole

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  • 文章类型: Case Reports
    一名29岁的女性在我们的不孕症诊所接受辅助生殖治疗(IVF),在胚胎移植后7w+2d的胎龄,在阴道超声检查中,子宫腔内没有可检测到的孕囊,β-hCG水平升高良好。施用第一剂量的MTX(78),同时β-hCG滴定110,000μg/mL。患者接受了第二次TVS,其中报告了有利于磨牙异位妊娠的肿块。由于怀疑磨牙EP,患者接受了剖腹探查术。切除位于右侧卵巢附近的3x4cm肿块。最终病理报告与磨牙部分妊娠相符。在手术切除后的随访期间,患者完全康复,无任何复发。
    A 29-year-old female who received assisted reproductive therapy (IVF) in our infertility clinic, at gestational age of 7w + 2d following embryo transfer, presented with a favorable rise of β-hCG level with no detectable gestational sac in the uterine cavity in the vaginal ultrasonogram. First dose of MTX (78) with simultaneous β-hCG titration of 110,000 pg/mL was administered. The patient underwent a second TVS in which a mass in favor of molar ectopic pregnancy was reported. With the suspicion of a molar EP the patient underwent explorative laparotomy. A 3x4 cm mass which was found adjacent to the right ovary was resected. Final pathology report was compatible with partial molar pregnancy. In the follow up period after surgical resection the patient recovered completely without any recurrence.
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  • 文章类型: Case Reports
    通常,葡萄胎(HM)在子宫内发育。在输卵管破裂妊娠中,HM的发生是例外的。文献中报道的病例很少。在这篇文章中,据报道,一例由完整的葡萄胎引起的输卵管破裂继发的腹膜出血。一名50岁的gravida2,para1因急性腹痛而被送往急诊科。经过临床检查,进行了腹部超声和CT扫描,显示存在与重要腹膜相关的附件左侧肿块。进行了尿液妊娠试验,呈阳性,表明立即进行腹腔镜探查。腹腔镜检查显示继发于输卵管肿块破裂的腹膜。病理检查得出结论,完全葡萄胎(CHM)侵入输卵管壁。潜在孕妇的任何急性腹痛首先会导致妊娠试验的常规实现。在破裂的输卵管中发生CHM特别罕见,并且在腹腔镜探查之前已被诊断出。
    Usually, a hydatidiform mole (HM) develops inside the uterus. The occurrence of HM in ruptured tubal pregnancy is exceptional. Cases reported in the literature are scarce. In this article, a case of haemoperitoneum secondary to a ruptured fallopian tube by a complete mole is reported. A 50-year-old gravida 2, para 1 was admitted to the emergency department for acute abdominal pain. After the clinical examination, an abdominal sonography and CT scan were done, revealing the presence of an adnexal left mass associated with an important haemoperitoneum. A urine pregnancy test was done and was positive, indicating an immediate laparoscopic exploration. The laparoscopy revealed a haemoperitoneum secondary to a ruptured tubal mass. The pathological exam concluded a complete hydatidiform mole (CHM) invading the wall of the fallopian tube. Any acute abdominal pain in a potentially pregnant woman imposes first the routine realization of a pregnancy test. The occurrence of CHM in a ruptured fallopian tube is particularly rare and has exceptionally been diagnosed before the laparoscopic exploration.
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  • 文章类型: Case Reports
    子宫手术是子宫破裂的常见诱发因素,而导致子宫破裂的侵袭性葡萄胎在临床上是罕见的。这里,我们报道一例31岁无子女妇女在怀孕53天后进行流产的病例.流产后,她仍然经历腹痛和少量阴道出血。她的人绒毛膜促性腺激素(HCG)水平很高,而超声和MRI结果显示子宫增大和子宫肌层肿块。在准备治疗期间,妇科医生使病人的子宫破裂,让她震惊。最终患者的子宫被切除子宫,病理诊断为侵袭性葡萄胎。
    Uterine surgery is a common predisposing factor for uterine rupture, while an invasive mole that leads to uterine rupture is a rare clinical occurrence. Here, we report a case of a 31-year-old childless woman who underwent abortion after 53 days of pregnancy. She still experienced abdominal pain and scanty vaginal bleeding after the abortion. Her levels of human chorionic gonadotropin (HCG) were high, while ultrasound and MRI results revealed an enlarged uterus and a mass in the myometrium. During preparation for treatment, the gynecologist ruptured the uterus of the patient, leaving her shocked. Eventually the patient\'s uterus was removed the uterus and pathologically diagnosed as result is the an invasive mole.
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  • 文章类型: Case Reports
    摩尔妊娠与甲状腺功能亢进和高血压疾病有关。磨牙和胎儿妊娠并存,非常罕见,有更高的并发症风险。
    我们描述了一例由于与磨牙妊娠相关的抗利尿激素分泌不当综合征(SIADH)引起的低钠血症。一名36岁的患者在妊娠13周时患有共存的磨牙妊娠,并伴有头痛,恶心,和呕吐。她被发现患有高血压,甲状腺功能亢进,还有低钠血症.用等渗盐水攻击进一步评估低钠血症,从而诊断为SIADH。患者接受了扩张和刮治,低钠血症得以解决。她后来发展为妊娠滋养细胞瘤。
    磨牙妊娠可出现不寻常的相关病症,比如SIADH。磨牙妊娠患者的低钠血症可能错误地归因于滋养细胞组织的其他副作用(甲状腺功能亢进,先兆子痫,或妊娠剧吐)。磨牙妊娠患者的低钠血症值得评估SIADH。
    UNASSIGNED: Molar pregnancies have been associated with hyperthyroidism and hypertensive disorders. Coexisting molar and fetal pregnancies, which are very rare, have an even higher risk of complications.
    UNASSIGNED: We describe a case of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) associated with a molar pregnancy. A 36-year-old patient at 13 weeks gestation with a coexisting molar pregnancy presented with headache, nausea, and vomiting. She was found to have hypertension, hyperthyroidism, and hyponatremia. The hyponatremia was further assessed with an isotonic saline challenge which resulted in a diagnosis of SIADH. The patient underwent dilation and curettage and her hyponatremia resolved. She later developed gestational trophoblastic neoplasia.
    UNASSIGNED: A molar pregnancy can present with unusual associated conditions, such as SIADH. Hyponatremia in a patient with molar pregnancy may be mistakenly attributed to other side effects of trophoblastic tissue (hyperthyroidism, pre-eclampsia, or hyperemesis gravidarum). Hyponatremia in a patient with a molar pregnancy warrants evaluation for SIADH.
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  • 文章类型: Case Reports
    Molar pregnancy or a hydatidiform mole, also referred to as gestational trophoblastic disease, is an abnormal type of pregnancy, in which a potentially anomalous egg is abnormally fertilized resulting in a subsequently non-viable conceptus becoming an enlarged growth in the uterus with dangerous complications. These moles can occur as either complete or partial moles, each with its own unique features. In this article, we report a case of a pregnant woman who presented to her primary care doctor with the chief complaint of shortness of breath. Upon further questioning, she was found to have slight vaginal bleeding. Further workup of the unexplained bleeding revealed a small, yet concerning molar pregnancy, and led to our encounter with the patient on her operating day for a dilation and curettage. As these moles are somewhat rare occurrences, this case report aims to describe the condition, with a focus on management and outcomes.
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