2010年全球疾病负担研究的目标是系统地对1990年至2010年291种疾病和伤害及其相关的1,160种后遗症的负担进行可比估计。我们的目的是在这里报告所有国家严重牙齿脱落的国内一致的患病率和发病率估计,20个年龄组,以及1990年和2010年的两性。对文献的系统搜索产生了5618篇独特的引文。标题和摘要经过筛选后,5,285篇引文被排除在外,因为显然与本系统综述无关,留下333份全文审查;在有效性评估后,265份出版物被进一步排除.使用2010年全球疾病负担研究的建模资源,共有68项研究-包括26个国家/地区的285,746名12岁或12岁以上的个体-被纳入荟萃分析。在1990年至2010年之间,全球年龄标准化人群的患病率从4.4%下降(95%的不确定区间:4.1%,4.8%)至2.4%(95%UI:2.2%,2.7%),发病率从每100,000人年374例(95%UI:347、406)下降到205例(95%UI:187、226)。2010年没有发现性别差异。患病率随年龄逐渐增加,在生命的第七个十年左右显示出急剧增加,这与65岁时的发病率高峰有关。患病率的地理差异,发病率,1990年至2010年的改善速度明显。我们对有关牙齿脱落流行病学的现有高质量文献的回顾显示,在全球范围内,1990年至2010年期间,严重牙齿脱落的患病率和发生率显着下降。区域,和国家层面。
The goal of the Global Burden of Disease 2010 Study has been to systematically produce comparable estimates of the burden of 291 diseases and injuries and their associated 1,160 sequelae from 1990 to 2010. We aimed to report here internally consistent prevalence and incidence estimates of severe tooth loss for all countries, 20 age groups, and both sexes for 1990 and 2010. The systematic search of the literature yielded 5,618 unique citations. After titles and abstracts were screened, 5,285 citations were excluded as clearly not relevant to this systematic
review, leaving 333 for full-text
review; 265 publications were further excluded following the validity assessment. A total of 68 studies-including 285,746 individuals aged 12 yr or older in 26 countries-were included in the meta-analysis using modeling resources of the Global Burden of Disease 2010 Study. Between 1990 and 2010, the global age-standardized prevalence of edentate people decreased from 4.4% (95% uncertainty interval: 4.1%, 4.8%) to 2.4% (95% UI: 2.2%, 2.7%), and incidence rate decreased from 374 cases per 100,000 person-years (95% UI: 347, 406) to 205 cases (95% UI: 187, 226). No differences were found by sex in 2010. Prevalence increased gradually with age, showing a steep increase around the seventh decade of life that was associated with a peak in incidence at 65 years. Geographic differences in prevalence, incidence, and rate of improvement from 1990 to 2010 were stark. Our
review of available quality literature on the epidemiology of tooth loss shows a significant decline in the prevalence and incidence of severe tooth loss between 1990 and 2010 at the global, regional, and country levels.