卵巢癌通常没有明显的症状，经常在晚期被诊断出来。它是妇科系统中最致命的癌症。我们对卵巢病理学的了解是有限的,需要使用多种标志物来准确检测卵巢癌，特别是当它表现异常时，如胸腔积液或淋巴结。一名45岁的妇女因腹痛持续两周而被送往急诊室（ER）。计算机断层扫描（CT）扫描显示腹膜癌病伴有腹水和淋巴结钙化。确定可能的主要来源是结肠或卵巢的粘液性腺癌。根据CT检查结果,对胃周淋巴结进行细针抽吸。组织病理学结果提示存在恶性细胞的低分化癌。“随后，插入了PowerPort，两天后开始辅助化疗，使用卡铂的组合，贝伐单抗,和紫杉醇。进行了穿刺术,产生清澈的黄色液体。然而,穿刺术后，腹部饱腹度再次逐渐增加。病人开始出现更剧烈的腹痛,特别是在左下象限。手术探索显示整个肠道广泛涉及疾病。我们的患者表现出卵巢癌的非典型表现，由于异位病灶和缺乏许多明显可识别的标记，对其鉴定提出了挑战。通过全面的测试和一个过程的消除，我们成功地将卵巢癌与其他潜在癌症区分开来。最终的组织病理学报告，伴随着显著升高的CA-125水平,为卵巢癌的可能最终诊断提供了实质性支持。尽管染色和鉴定技术取得了许多进步，卵巢癌的诊断仍未得到充分了解。在没有清晰可视化的情况下识别卵巢癌通常具有挑战性，进一步的研究是必要的，以提高我们对病理方法的理解。此外，有必要优先开发和探索卵巢癌筛查和测试方法，以防止疾病延迟检测。
Ovarian carcinoma often doesn\'t show noticeable symptoms and is frequently diagnosed at an advanced stage. It is the most fatal cancer within the gynecologic system. Our understanding of ovarian pathology is limited, necessitating the use of multiple markers to accurately detect ovarian cancer, particularly when it presents abnormally, such as in pleural effusion or lymph nodes. A 45-year-old woman presented to the emergency room (ER) due to abdominal pain lasting for two weeks. A computed tomography (CT) scan revealed peritoneal carcinomatosis accompanied by ascites and calcification in the lymph nodes. The likely primary sources were determined to be mucinous adenocarcinomas from either the colon or ovary. Following the CT findings, a fine needle aspiration was conducted on a perigastric lymph node. Histopathology results indicated a \"poorly differentiated carcinoma [with] malignant cells present.\" Subsequently, a PowerPort was inserted, and adjuvant chemotherapy commenced two days later, utilizing a combination of carboplatin, bevacizumab, and paclitaxel. Paracentesis was performed, yielding clear-yellow fluid. However, abdominal fullness gradually increased again after paracentesis. The patient began experiencing more intense abdominal pain, particularly in the left lower quadrant. Surgical exploration revealed widespread disease involvement throughout the intestines. Our patient exhibited an atypical manifestation of ovarian carcinoma, challenging its identification due to ectopic foci and the absence of many distinctly identifiable markers. Through comprehensive testing and a process of elimination, we successfully differentiated ovarian carcinoma from other potential cancers. The conclusive histopathological report, along with a markedly elevated CA-125 level, provided substantial support for the probable final diagnosis of ovarian carcinoma. Despite numerous advancements in staining and identification techniques, the diagnosis of ovarian carcinoma remains inadequately understood. Identifying ovarian carcinoma without clear visualization is often challenging, and further research is warranted to enhance our understanding of pathological methods. Moreover, there is a need to prioritize the development and exploration of ovarian carcinoma screening and testing methods to prevent delayed disease detection.
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