目的:将经皮足底内侧神经刺激(T-MPNS)定义为一种新的神经调节方法,并评估T-MPNS对特发性膀胱过度活动症(OAB)女性患者生活质量(QoL)和与尿失禁相关的临床参数的影响。
方法:21名女性纳入本研究。所有女性均接受T-MPNS。将两个自粘表面电极放置在脚内侧的大脚趾的meta骨-趾关节附近的负电极和内踝下后侧2cm的正电极(在中踝-跟骨轴的前方)。每周2天进行T-MPNS,一天30分钟,共12个疗程,为期6周。对女性进行失禁严重程度评估(24小时垫测试),3天排尿日记,症状严重程度(膀胱过度活动症问卷[OAB-V8]),生活质量-失禁影响问卷[IIQ-7]积极反应和治愈改善率,基线和第6周的治疗满意度。
结果:在失禁的严重程度上发现了统计学上的显着改善,排尿的频率,失禁发作,夜尿症,垫的数量,症状严重程度,与基线相比,第6周的QoL参数。治疗满意度,治疗成功,发现治愈或改善率在第6周很高。
结论:T-MPNS在文献中首次被描述为一种新的神经调节方法。我们得出的结论是,T-MPNS对特发性OAB女性的临床参数和与失禁相关的QoL均有效。需要随机对照多中心研究来验证T-MPNS的有效性。
OBJECTIVE: To define transcutaneous medial plantar nerve stimulation (T-MPNS) as a new neuromodulation method and assess the efficacy of T-MPNS on quality of life (QoL) and clinical parameters associated with incontinence in women with idiopathic overactive bladder (OAB).
METHODS: Twenty-one women were included in this study. All women received T-MPNS. Two self-adhesive surface electrodes were positioned with the negative electrode near the metatarsal-phalangeal joint of the great toe on the medial aspect of the foot and the positive electrode 2 cm inferior-posterior of the medial malleolus (in front of the medio-malleolar-calcaneal axis). T-MPNS was performed 2 days a week, 30 minutes a day, for a total of 12 sessions for 6 weeks. Women were evaluated for incontinence severity (24-h pad test), 3-day voiding diary, symptom severity (Overactive Bladder Questionnaire [OAB-V8]), QoL (Quality of Life-Incontinence Impact Questionnaire [IIQ-7]), positive response and cure-improvement rates, and treatment satisfaction at baseline and at the 6th week.
RESULTS: Statistically significant improvement was found in the severity of incontinence, frequency of voiding, incontinence episodes, nocturia, number of pads, symptom severity, and QoL parameters at the 6th week compared with baseline. Treatment satisfaction, treatment success, and cure or improvement rates were found to be high at the 6th week.
CONCLUSIONS: T-MPNS was first described in the literature as a new neuromodulation method. We conclude that T-MPNS is effective on both clinical parameters and QoL associated with incontinence in women with idiopathic OAB. Randomized controlled multicenter studies are needed to validate the effectiveness of T-MPNS.