生物力学工程师和物理学家通常使用生物骨进行生物力学研究,因为它们是活骨头的好代表。然而,使用生物骨骼面临挑战,比如成本,降解,疾病,伦理,航运,采购,storage,可变性,等。因此,Synbone®公司开发了一系列合成骨骼,这些骨骼已被生物力学研究人员用来弥补生物骨骼的一些缺点。已经有许多公开的生物力学报告使用这些骨骼替代品进行牙科,损伤,骨科,和其他应用。但是,没有以前的综述论文总结了这些合成骨的机械性能,以了解它们的一般性能或它们如何代表生物骨。因此,本文的目的是调查有关这些合成骨骼的机械性能的英语文献。如果定量地(a)表征合成骨的先前未知值,(b)经过验证的合成与生物骨,和/或(c)通过改变几何或材料参数来优化合成骨性能。这次数据审查,趋势,优点,缺点,未来的工作将有望帮助使用这些合成骨骼的生物力学工程师和物理学家开发实验测试方案和计算有限元模型。
Biomechanical engineers and physicists commonly employ biological bone for biomechanics studies, since they are good representations of living bone. Yet, there are challenges to using biological bone, such as cost, degradation, disease, ethics, shipping, sourcing, storage, variability, etc. Therefore, the Synbone® company has developed a series of synthetic bones that have been used by biomechanical investigators to offset some drawbacks of biological bone. There have been a number of published biomechanical reports using these bone surrogates for dental, injury, orthopedic, and other applications. But, there is no prior
review paper that has summarized the
mechanical properties of these synthetic bones in order to understand their general performance or how well they represent biological bone. Thus, the goal of this article was to survey the English-language literature on the
mechanical properties of these synthetic bones. Studies were included if they quantitatively (a) characterized previously unknown values for synthetic bone, (b) validated synthetic versus biological bone, and/or (c) optimized synthetic bone performance by varying geometric or material parameters. This
review of data, pros, cons, and future work will hopefully assist biomechanical engineers and physicists that use these synthetic bones as they develop experimental testing regimes and computational models.