■崩解胱氨酸和草酸钙一水合物结石由于其硬度和独特的组成而提出了巨大的挑战。这项研究旨在为这些硬石碎石术建立最佳的激光设置。
■从两名患者中提取胱氨酸和草酸钙一水合物结石。通过使用具有可变设置的272μm激光纤维分解胱氨酸和草酸钙一水合物结石,在体外进行了两个实验。在第一个实验中,能量是可调的,而频率是恒定的,而第二个实验涉及在每种类型的石头上具有可调频率的恒定能量,每个实验重复三次以确保鲁棒性和可靠性。
■我们的研究结果表明,对于胱氨酸结石,使用更高的总功率与高能量和低频率被证明是有效的。相反,对于草酸钙一水合物结石,涉及低能量和高频率的更高总功率的设置显示出优异的疗效和安全性。
■总功率较高的钬(Ho:YAG)激光器设置,高能量,尽管热量增加,低频仍可有效崩解胱氨酸结石,这是通过带有热电偶的温度计测量的。对于草酸钙一水合物结石,更高的总功率,高频,和低能量设置建议和安全。
UNASSIGNED: Disintegrating cystine and calcium oxalate monohydrate stones present a formidable challenge owing to their hardness and distinct composition. This
study aimed to establish optimal laser settings for these hard stones lithotripsy.
UNASSIGNED: Cystine and calcium oxalate monohydrate stones were extracted from two patients. Two experiments were conducted in vitro by utilizing a 272 μm laser fiber with variable settings to disintegrate the cystine and calcium oxalate monohydrate stones. In the first experiment, energy was adjustable while frequency was constant, whereas the second experiment involved constant energy with adjustable frequency on each type of stone and each experiment was repeated three times to ensure robustness and reliability.
UNASSIGNED: Our findings indicated that for cystine stones, use of higher total power with high energy and low frequency proved to be effective. Conversely, for calcium oxalate monohydrate stones, settings involving higher total power with low energy and high frequency demonstrated superior efficacy and safety.
UNASSIGNED: Holmium (Ho: YAG) laser settings with higher total power, high energy, and low frequency effectively disintegrate cystine stones despite increased heat, which was measured by a thermometer with a thermocouple. For calcium oxalate monohydrate stones, higher total power, high frequency, and low energy settings are recommended and safe.