目的:通过评估已发表的治疗方法和推荐治疗方案,为与Sjögren病相关的干眼病的治疗提供共识的临床指南。
方法:报告的干眼病治疗方法的共识小组评估。
方法:以2007年国际干眼研讨会(DEWS)报告为起点,一个由眼部护理提供者和顾问组成的小组评估了同行评审的出版物,并提出了与Sjögren病相关的干眼病的评估和管理建议.出版物根据美国眼科学会首选实践模式指南的证据水平进行分级。推荐的力度是根据推荐评估的分级,开发和评估(等级)指南。
结果:本文简要概述了专家组的建议。评估应包括不适和视觉障碍的症状,以及确定水性产生不足和泪液体积蒸发损失的相对贡献。泪膜稳定性的客观参数,泪液渗透压,眼睑边缘疾病的程度,眼表损伤应用于判断干眼症的严重程度,以帮助选择合适的治疗方案。关于问题性质的患者教育,加重因素,治疗目标是成功管理的关键。泪液补充和稳定,控制泪腺和眼表的炎症,和泪液产生的可能刺激是根据干眼病的特征和严重程度使用的治疗选择。
结论:提供了与Sjögren病相关的干眼管理指南。
OBJECTIVE: To provide a
consensus clinical
guideline for management of dry eye disease associated with Sjögren disease by evaluating published treatments and recommending management options.
METHODS: Consensus panel evaluation of reported treatments for dry eye disease.
METHODS: Using the 2007 Report of the International Workshop on Dry Eye (DEWS) as a starting point, a panel of eye care providers and consultants evaluated peer-reviewed publications and developed recommendations for evaluation and management of dry eye disease associated with Sjögren disease. Publications were graded according to the American Academy of Ophthalmology Preferred Practice Pattern
guidelines for level of evidence. Strength of recommendation was according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE)
guidelines.
RESULTS: The recommendations of the panel are briefly summarized herein. Evaluation should include symptoms of both discomfort and visual disturbance as well as determination of the relative contribution of aqueous production deficiency and evaporative loss of tear volume. Objective parameters of tear film stability, tear osmolarity, degree of lid margin disease, and ocular surface damage should be used to stage severity of dry eye disease to assist in selecting appropriate treatment options. Patient education with regard to the nature of the problem, aggravating factors, and goals of treatment is critical to successful management. Tear supplementation and stabilization, control of inflammation of the lacrimal glands and ocular surface, and possible stimulation of tear production are treatment options that are used according to the character and severity of dry eye disease.
CONCLUSIONS: Management
guidelines for dry eye associated with Sjögren\'s disease are presented.