kidney stones

肾结石
  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景:由不同协会发布的指南中报告的基于石头负担的管理策略长期以来众所周知。鹿角结石,代表着最大的负担和最复杂的石头,是临床实践中泌尿科医师最具挑战性的病例之一。国际尿石症联盟(IAU)发布了一系列关于尿石症管理的指南。
    目的:为鹿角形结石的现代管理提供一系列建议,并为泌尿科医生治疗这些复杂结石患者提供临床框架。
    方法:对1976年1月1日至2022年12月31日在PubMed上发表的英文文章进行全面的文献搜索,OVID,执行Embase和Medline数据库。在文献回顾和小组讨论之后,制定了一系列建议并进行了单独分级。
    结果:定义,发病机制,病理生理学,术前评估,术中治疗策略和程序建议,术后早期管理,本文总结了结石复发的随访和预防。
    结论:关于鹿角形结石治疗的一系列建议,本指南中提供的相关评论和支持文件旨在为执业泌尿科医师管理鹿角形结石提供临床框架.
    BACKGROUND: The stone burden based management strategy reported in the guidelines published by different associations is well known for a long time. Staghorn calculi, representing the largest burden and most complex stones, is one of the most challenging cases to practicing urologists in clinical practice. The International Alliance of Urolithiasis (IAU) has released a series of guidelines on the management of urolithiasis.
    OBJECTIVE: To develop a series of recommendations for the contemporary management management of staghorn calculi and to provide a clinical framework for urologists treating patients with these complex stones.
    METHODS: A comprehensive literature search for articles published in English between 01/01/1976 and 31/12/2022 in the PubMed, OVID, Embase and Medline database is performed. A series of recommendations are developed and individually graded following the review of literature and panel discussion.
    RESULTS: The definition, pathogenesis, pathophysiology, preoperative evaluation, intraoperative treatment strategies and procedural advice, early postoperative management, follow up and prevention of stone recurrence are summarized in the present document.
    CONCLUSIONS: A series of recommendations regarding the management of staghorn calculi, along with related commentary and supporting documentation offered in the present guideline is intended to provide a clinical framework for the practicing urologists in the management of staghorn calculi.
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  • 文章类型: Review
    目的:欧洲泌尿外科协会(EAU)更新了2021年尿石症临床最佳实践指南。因此,我们旨在总结上尿路结石患者手术干预的最佳临床实践。
    方法:小组对截至2021年5月的新数据进行了全面的文献综述。更新了指南,并为每个建议给出了强度等级,使用修改后的“建议分级”进行分级,评估,发展,和评价方法。
    结果:手术干预的选择取决于结石的特征,病人解剖学,合并症,和选择。对于冲击波碎石术(SWL),最佳冲击频率为1.0-1.5Hz。对于输尿管镜检查(URS),在不复杂的情况下,不需要术后支架。如果禁用经皮肾镜取石术(PCNL)或SWL,则可选择柔性URS,即使是>2厘米的石头。对于PCNL,俯卧和仰卧方法同样安全。对于不复杂的PCNL病例,PCNL后不需要肾造瘘管。腔内手术的辐射暴露应遵循尽可能低的合理可实现的原则。
    结论:这是关于尿石症介入治疗最佳临床实践的EAU尿石症指南的总结。完整的指南可在https://uroweb.org/guidelines/尿石症上获得。
    结果:欧洲泌尿外科协会制定了关于肾结石最佳治疗的指南,本文对此进行了总结。肾结石疾病是一种常见病;计算机断层扫描(CT)越来越多地用于诊断它。该指南旨在通过减少X射线和CT扫描的使用来减少对患者的辐射暴露。我们详细介绍了肾结石常见手术的具体建议。
    The European Association of Urology (EAU) has updated its guidelines on clinical best practice in urolithiasis for 2021. We therefore aimed to present a summary of best clinical practice in surgical intervention for patients with upper tract urolithiasis.
    The panel performed a comprehensive literature review of novel data up to May 2021. The guidelines were updated and a strength rating was given for each recommendation, graded using the modified Grading of Recommendations, Assessment, Development, and Evaluations methodology.
    The choice of surgical intervention depends on stone characteristics, patient anatomy, comorbidities, and choice. For shockwave lithotripsy (SWL), the optimal shock frequency is 1.0-1.5 Hz. For ureteroscopy (URS), a postoperative stent is not needed in uncomplicated cases. Flexible URS is an alternative if percutaneous nephrolithotomy (PCNL) or SWL is contraindicated, even for stones >2 cm. For PCNL, prone and supine approaches are equally safe. For uncomplicated PCNL cases, a nephrostomy tube after PCNL is not necessary. Radiation exposure for endourological procedures should follow the as low as reasonably achievable principles.
    This is a summary of the EAU urolithiasis guidelines on best clinical practice in interventional management of urolithiasis. The full guideline is available at https://uroweb.org/guidelines/urolithiasis.
    The European Association of Urology has produced guidelines on the best management of kidney stones, which are summarised in this paper. Kidney stone disease is a common condition; computed tomography (CT) is increasingly used to diagnose it. The guidelines aim to decrease radiation exposure to patients by minimising the use of x-rays and CT scans. We detail specific advice around the common operations for kidney stones.
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  • 文章类型: Journal Article
    简介:由于担心可能造成胎儿伤害的调查和治疗,怀孕期间肾结石的管理可能会给泌尿科医师带来压力。并且不熟悉这些复杂患者的最佳管理。作为回应,我们制定了基于多学科证据的指南,以规范出现侧腹疼痛和怀疑肾结石的产科患者的护理.方法:涉及泌尿外科的多学科团队,产科麻醉学,妇产科,放射诊断学,和介入放射学从一个学术医疗中心组装。使用怀孕/产前的关键字进行PubMed搜索,肾结石/结石/肾结石,输尿管镜检查,非产科手术,并发症,早产,MRI,计算机断层扫描,肾膀胱超声(RBUS),和麻醉识别相关文章。团队成员审查了各自的领域,以创建一套全面的指导方针。一位受邀的外部专家为验证目的审查了准则。结果:共审查54篇文献进行证据综合。构建了四个指南声明来指导诊断和成像,和七个声明来指导干预。然后使用指南来创建诊断和干预流程图,以便于使用。总之,RBUS应该是最初的诊断研究。如果诊断不确定性仍然存在,应进行非造影CT扫描.对于出现脓毒性阻塞结石的产科患者,应该实现紧急减压。如果局部因素允许,我们建议将输尿管支架置入术作为首选干预措施。结论:我们为妊娠期肾结石的管理提供了标准化的护理路径。我们的目标是标准化和简化泌尿科医师对这些复杂情况的临床管理。
    Introduction: The management of nephrolithiasis during pregnancy can be stressful for urologists due to concerns for investigations and treatments that may pose risk of fetal harm, and unfamiliarity with optimal management of these complex patients. In response, we created multi-disciplinary evidence-based guidelines to standardize the care for obstetric patients presenting with flank pain and suspicion for nephrolithiasis. Methods: A multi-disciplinary team involving Urology, Obstetric Anesthesiology, Obstetrics and Gynecology, Diagnostic Radiology, and Interventional Radiology from a single academic medical center was assembled. A PubMed search was performed using keywords of pregnancy/antepartum, nephrolithiasis/calculi/kidney stones, ureteroscopy, non-obstetric surgery, complications, preterm delivery, MRI, computerized tomography, renal bladder ultrasound (RBUS), and anesthesia to identify relevant articles. Team members reviewed their respective areas to create a comprehensive set of guidelines. One invited external expert reviewed the guidelines for validation purposes. Results: A total of 54 articles were reviewed for evidence synthesis. Four guideline statements were constructed to guide diagnosis and imaging, and seven statements to guide intervention. Guidelines were then used to create a diagnostic and intervention flowchart for ease of use. In summary, RBUS should be the initial diagnostic study. If diagnostic uncertainty still exists, a non-contrast CT scan should be obtained. For obstetric patients presenting with a septic obstructing stone, urgent decompression should be achieved. We recommend ureteral stent placement as the preferred intervention if local factors allow. Conclusions: We present a standardized care pathway for the management of nephrolithiasis during pregnancy. Our aim is to standardize and simplify the clinical management of these complex scenarios for urologists.
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