■巨大角化棘皮瘤,一种罕见的孤立性角化棘皮瘤的特征是直径超过20毫米,快速增长,和破坏下面的组织。传统上,它被认为是自我解决或低级别鳞状细胞增生。由于它们的非典型外观,巨大角化棘皮瘤可能存在诊断挑战。组织病理学检查仍然是区分鳞状细胞癌(SCC)和角化棘皮瘤的参考标准。手术治疗仍然是孤立性角化棘皮瘤的标准治疗方法。
我们介绍了一个75岁的男子,脸颊上有一个巨大的角化棘皮瘤,横向长度为25毫米,纵向长度为30毫米,位于耳垂下方30毫米,经手术切除,随访期间无明显复发。我们使用了术中冰冻切片检查,这在确保清晰的边缘和完整的肿瘤切除方面发挥了至关重要的作用。
■该病例表明,角化棘皮瘤可以通过手术治愈,应与SCC和其他圆形肿瘤区分开来。手术切除面部巨大孤立性角化棘皮瘤后,应考虑美容问题的高风险。我们建议进行游离皮瓣移植进行功能修复,当肿瘤的侵袭范围较大并形成穿孔缺损时。
UNASSIGNED: Giant
keratoacanthoma, a rare variant solitary of
keratoacanthoma is characterized by a diameter exceeding 20 mm, rapid growth, and destruction of underlying tissue. Traditionally, it has been considered to be a self-resolving or low-grade squamous proliferation. Due to their atypical appearance, Giant keratoacanthomas may present a diagnostic challenge. Histopathological examination remains the reference standard for distinguishing squamous cell carcinoma (SCC) from keratoacanthoma. Surgical management is still the standard treatment for solitary
keratoacanthoma.
UNASSIGNED: We present the case of a 75-year-old man with a giant
keratoacanthoma of the cheek, with a transverse length of 25 mm and a longitudinal length of 30 mm located 30 mm below the earlobe that was surgically excised with no obvious recurrence during follow-up. We used the Intraoperative frozen-section examination, which played a crucial role in ensuring clear margins and complete tumor removal.
UNASSIGNED: This case demonstrates that
keratoacanthoma can be considered surgically curable and should be distinguished from SCC and other crateriform tumors. After surgical resection of giant isolated
keratoacanthoma on the face, the high risk of cosmetic problems should be considered. We suggest free-flap transplantation be performed for functional repair, when the invasion range of the tumor is large and a perforation defect is formed.