■我们旨在确定日本糖尿病患者足部溃疡前病变的频率和危险因素。
■这是一项单中心横断面观察性研究。我们对5029名糖尿病患者(平均年龄63岁;2185名女性;1015名1型糖尿病患者和4014名2型糖尿病患者)进行了问卷调查,他们(a)参加了东京女子医科大学中心的糖尿病研究:DIACET2018,(b)对足部溃疡前病变的存在做出回应。足部溃疡前病变被定义为老茧,向内生长的指甲,或真菌感染的症状。使用逻辑回归分析检查了足部溃疡前病变与常用临床信息之间的关联。
■1015例(40.6%)1型糖尿病患者中的412例和4014例(39.5%)2型糖尿病患者中的1585例报告有任何类型的足部溃疡前病变。老茧的频率,向内生长的指甲,和真菌感染的症状,分别,为16.8%,15.8%,1型糖尿病占21.9%,10.5%,18.5%,2型糖尿病患者为24.7%。在按糖尿病类型进行的单独分析中,发现与足部溃疡前病变显著相关的常见危险因素是女性,麻木在脚和脚变形。
■卫生保健专业人员主动进行足部筛查被认为很重要,特别是在1型和2型糖尿病患者中,有晚期并发症和足部变形。
■在线版本包含补充材料,可在10.1007/s13340-023-00649-7获得。
UNASSIGNED: We aimed to identify the frequency and risk factors of pre-ulcerative lesions of foot in Japanese individuals with diabetes.
UNASSIGNED: This was a single-center cross-sectional observational
study. We conducted a questionnaire survey of 5029 individuals with diabetes (mean age 63 years; 2185 women; 1015 individuals with type 1 diabetes and 4014 individuals with type 2 diabetes) who (a) participated in the Diabetes
Study from the Center of Tokyo Women\'s Medical University: DIACET 2018, and (b) responded to the presence of pre-ulcerative lesions of foot. A pre-ulcerative lesions of foot was defined as a calluses, ingrown nails, or symptoms of fungal infection. The associations between pre-ulcerative lesions of foot and commonly available clinical information were examined using the logistic regression analysis.
UNASSIGNED: 412 of 1015 (40.6%) individuals with type 1 diabetes and 1585 of 4014 (39.5%) individuals with type 2 diabetes reported having any type of pre-ulcerative lesions of foot. The frequency of calluses, ingrown nails, and symptoms of fungal infection, respectively, were 16.8%, 15.8%, and 21.9% in type 1 diabetes and 10.5%, 18.5%, and 24.7% in type 2 diabetes. In the separate analysis by type of diabetes, common risk factors found to be significantly correlated with pre-ulcerative lesions of foot were female gender, numbness in the feet and foot deformation.
UNASSIGNED: Proactive foot screening by health care professionals was considered important, especially in individuals with type 1 and type 2 diabetes with advanced complications and foot deformation.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s13340-023-00649-7.