INFOGEST国际财团开发的体外消化模型广泛用于模拟人体胃肠道内部发生的物理化学过程(口,胃,和小肠)在食物消化过程中。在这次审查中,我们简要概述了INFOGEST方法和用于测量大量营养素消化的程序(脂质,蛋白质,和淀粉),生物活性剂(维生素,矿物,和营养食品),以及胃肠条件下食物结构和物理性质的变化(颗粒大小,charge,和位置)。然后,我们回顾了INFOGEST方法在监测不同种类食物和饮料的胃肠道命运中的应用,包括乳制品,鸡蛋,肉,海鲜,水果,蔬菜,麦片,和乳化产品。我们还讨论了这种方法在研究下一代植物性食品消化率方面的应用,比如肉,海鲜,乳制品,和鸡蛋类似物。最后,评估了这种标准化体外消化模型的益处和局限性.食品科学与技术年度评论的预计最终在线出版日期,第14卷是2023年3月。请参阅http://www。annualreviews.org/page/journal/pubdates的订正估计数。
The in vitro digestion model developed by the INFOGEST international consortium is widely used to simulate the physicochemical processes occurring inside the human gastrointestinal tract (mouth, stomach, and small intestine) during the digestion of foods. In this
review, we provide a brief overview of the INFOGEST method and the procedures used to measure the digestion of macronutrients (lipids, proteins, and starch), the bioaccessibility of bioactive agents (vitamins, minerals, and nutraceuticals), and the changes in the structure and physical properties of foods under gastrointestinal conditions (particle size, charge, and location). We then
review the application of the INFOGEST method for monitoring the gastrointestinal fate of different kinds of foods and beverages, including dairy, egg, meat, seafood, fruit, vegetable, cereal, and emulsified products. We also discuss the application of this method for studying the digestibility of next-generation plant-based foods, such as meat, seafood, dairy, and egg analogs. Finally, the benefits and limitations of this standardized in vitro digestion model are assessed.