背景:这项研究调查了在英国使用自己动手的人工胰腺系统(DIYAPS),以及与之相关的自我报告结果是否受到用户人口统计的影响。
方法:进行了一项在线调查,以评估用户人口统计数据和自我报告的时间范围(TIR)结果。进行统计分析以审查结果,并检查TIR随年龄的变化是否存在重大差异,性别和糖尿病的持续时间。
结果:在广泛的用户年龄范围内对调查的253个有效答复中,74.4%与成年用户有关,25.6%与16岁以下儿童有关。大多数(65.6%)使用AndroidAPS,但16岁以下儿童使用Loop的比例(43.1%)高于成年人(25.9%)。相应地,使用OmnipodEros的16岁以下儿童(40.0%)比成年人(24.3%)多。据报道,所有参与者的时间范围增加了17.3%(±13.7%),年龄组之间没有观察到显著差异,性别或糖尿病病程组(p>0.05)。
结论:结果表明,男女都在使用这些系统,并且用户涵盖了广泛的年龄和糖尿病持续时间。他们还表明,自我报告的DIYAPS医疗保健结果的改善可能并非特定于任何特定年龄,性别或糖尿病的持续时间,并且结果可以通过人口统计提供对算法适用性的额外见解。这项研究还可以告知医疗保健专业人员有关DIYAPS解决方案的使用和有效性。
BACKGROUND: This study investigates the use of do-it-yourself artificial pancreas systems (DIYAPS) in the UK, and whether self-reported outcomes associated with them are affected by the demographics of the user.
METHODS: An online survey was conducted to assess user demographic data and self-reported time-in-range (TIR) outcomes. Statistical analysis was undertaken to
review the results and check whether there were major differences in change in TIR across age, gender and duration of diabetes.
RESULTS: Of 253 valid responses to the survey across a wide age range of users, 74.4% related to adult users and 25.6% related to under-16s. The majority (65.6%) used AndroidAPS, but there was greater use of Loop (43.1%) amongst under-16s than amongst adults (25.9%). Correspondingly, more under-16s (40.0%) than adults (24.3%) used Omnipod Eros. A 17.3% (± 13.7%) increase in time in range was reported across all participants, with no significant differences observed between age groups, genders or diabetes duration groups (p > 0.05).
CONCLUSIONS: The results show that these systems are being used by both genders, and that users cover a wide range of ages and diabetes durations. They also show that improvements in self-reported DIYAPS healthcare outcomes may not be specific to any particular age, gender or duration of diabetes, and the results may provide additional insights into the applicability of the algorithms by demographic. This study may also inform healthcare professionals about the use and effectiveness of DIYAPS solutions.