hospital discharge

医院出院
  • 文章类型: Journal Article
    多项研究探索了患者的需求和经历,家庭成员,和医疗保健专业人员关于医院到家庭的过渡。我们的研究旨在确定,批判性评价,并在定性的荟萃综合中总结这些研究。
    Medline,从开始到2024年6月,对CINAHL和Embase进行了系统搜索,以确定合格的文章。纳入了定性研究,并使用关键评估技能计划进行了严格评估。不包括质量不足的论文。在(1)由两名独立研究人员进行开放编码和(2)在反身会议期间讨论代码之后,我们进行了元合成。
    对98项研究进行了评估,其中包括53个。我们达到了主题饱和,构建了四个主题:(1)护理协调和连续性,(2)沟通,(3)患者和家庭参与,(4)个性化支持和信息交流。对于患者和家属来说,定制的信息和支持是出院后无缝过渡和最佳恢复轨迹的先决条件。医疗保健专业人员必须在护理环境内和跨护理环境进行有效沟通,以确保多学科协作和护理连续性。
    这项研究确定了最佳过渡护理的基本要素。当(重新)设计过渡性护理干预措施以确保出院后的护理连续性时,这些发现可能会支持研究人员和医疗保健专业人员。
    患者及其家属需要获得量身定制的信息和支持,从医院到家庭的无缝过渡的先决条件专业人员必须在医院和初级保健设置内部和之间进行有效的沟通。应澄清专业角色,以确保出院后的有效协作和持续的高质量护理。需要解决协调和沟通的综合联合卫生途径,以确保无缝过渡。
    UNASSIGNED: Multiple studies have explored the needs and experiences of patients, family members, and healthcare professionals regarding hospital-to-home transitions. Our study aimed to identify, critically appraise, and summarize these studies in a qualitative meta-synthesis.
    UNASSIGNED: Medline, CINAHL and Embase were systematically searched to identify eligible articles from inception to June 2024. Qualitative studies were included and critically appraised using the Critical Appraisal Skills Program. Insufficient-quality papers were excluded. We performed a meta-synthesis following (1) open coding by two independent researchers and (2) discussing codes during reflexivity meetings.
    UNASSIGNED: Ninety-eight studies were appraised, of which 53 were included. We reached thematic saturation, four themes were constructed: (1) care coordination and continuity, (2) communication, (3) patient and family involvement, and (4) individualized support and information exchange. For patients and families, tailored information and support are prerequisites for a seamless transition and an optimal recovery trajectory after hospital discharge. It is imperative that healthcare professionals communicate effectively within and across care settings to ensure multidisciplinary collaboration and care continuity.
    UNASSIGNED: This study identifies essential elements of optimal transitional care. These findings could be supportive to researchers and healthcare professionals when (re)designing transitional care interventions to ensure care continuity after hospital discharge.
    Patients and their families need to receive tailored information and support, which are prerequisites for a seamless transition from hospital to homeProfessionals must communicate effectively within and across hospital and primary care settingsProfessional roles should be clarified to ensure effective collaboration and continued high-quality care after hospital discharge.Integrated allied health pathways addressing coordination and communication are needed to ensure seamless transitions.
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  • 文章类型: Journal Article
    背景:越来越多的国家报告阿片类镇痛药的使用和危害急剧增加。在术后患者中观察到新阿片类药物的高发生率。作为回应,各三级医疗机构制定了阿片类药物退出计划(OEP),以遏制潜在的阿片类药物相关危害.
    方法:系统搜索PubMed和Embase,总结,并比较了2000年1月1日至2024年6月4日发表的术后患者人群的OEP介入要素。两名研究人员根据PRISMA2020指南独立筛选了这些文章的资格,提取数据,并评估研究质量和偏倚风险。对研究特征进行了数据合成,干预细节,功效,和发展。
    结果:共筛选了2,585篇文章,其中八个符合资格标准。所有研究均在北美进行,重点是全髋关节或膝关节置换术(n=5)或神经外科(n=3)后的骨科手术患者。大多数研究(n=7)包括pre-post(n=4)或随机临床设计(n=3)。三项研究质量很好,没有一个有偏见的风险很低。干预措施各不相同,范围从教育课程(n=1)到个性化的锥形协议(n=4)或两者的组合(n=2)。关键要素是关于如何预测患者术后对阿片类镇痛药的需求以及基于24小时出院前阿片类药物消耗的逐渐减少策略的说明。六项研究将疗效作为其分析的终点,其中四个评估了统计学意义,4人都确认OEP成功减少了术后阿片类药物的使用.
    结论:尽管在设计和实现方面存在差异,经鉴定的OEP表明,它们可有效减少门诊阿片类药物的消耗.它们提供了术后镇痛需求的可靠估计以及逐渐减少持续时间和速率的基本原理。然而,需要更严格的研究来评估它们在现实世界中的有效性。
    BACKGROUND: A growing number of countries have reported sharp increases in the use and harm of opioid analgesics. High rates of new opioid initiation are observed in postoperative patients. In response, various tertiary care institutions have developed opioid exit plans (OEPs) to curb potential opioid-related harm.
    METHODS: PubMed and Embase were systematically searched to identify, summarize, and compare the interventional elements of OEPs for postoperative patient populations published from January 1, 2000, to June 4, 2024. Two researchers independently screened the articles for eligibility following the PRISMA 2020 guidelines, extracted the data, and assessed the study quality and risk of bias. Data synthesis was performed for study characteristics, intervention details, efficacy, and development.
    RESULTS: A total of 2,585 articles were screened, eight of which met the eligibility criteria. All studies were conducted in North America and focused on orthopedic surgery patients following total hip or knee arthroplasty (n = 5) or neurosurgery (n = 3). Most studies (n = 7) included a pre-post (n = 4) or randomized clinical design (n = 3). Three studies were of good quality, and none had a low risk of bias. The interventions varied and ranged from educational sessions (n = 1) to individualized tapering protocols (n = 4) or a combination of the two (n = 2). Key elements were instructions on how to anticipate patients\' postoperative need for opioid analgesics and tapering strategies based on 24-h predischarge opioid consumption. Six studies included efficacy as an endpoint in their analysis, of which four assessed statistical significance, with all four identifying that the OEPs were successful in reducing postoperative opioid use.
    CONCLUSIONS: Despite differences in design and implementation, the identified OEPs suggest that they are efficacious in reducing outpatient opioid consumption. They provide a robust estimate of postoperative analgesic requirements and a rationale for tapering duration and rate. However, more rigorous studies are needed to evaluate their real-world effectiveness.
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  • 文章类型: Journal Article
    出院通常与缺乏连续性有关,导致护理分散,特别是在低收入国家。由于有关这些国家干预措施的信息有限,并且没有评估出院干预措施有效性的研究,我们进行了范围审查,以确定有效的从医院到家庭的过渡性护理干预措施,并探讨其在低收入国家(苏丹)的适用性.
    我们对系统评价和荟萃分析的范围审查将干预措施归类为有效的,无效,不受欢迎的,或者不确定,根据他们的证据质量和他们对以下结果的估计影响:再入院率,死亡率,成本,生活质量,和不良结果)和证据的确定性。我们来自苏丹的作者使用SUPPORT摘要工具来确定是否可以在苏丹实施三种有效的干预措施。
    在确定的3,276篇文章中,回顾了72篇文章,审查中包含了10篇文章。七种干预措施被归类为有效的,一个是无效的,也没有不良影响。八种干预措施被归类为效果不确定。有效的干预措施包括家访,信息和通信技术(ICT),案例管理器模型,多学科团队,和自我管理支持。
    这项研究的发现表明,结合两到四种干预措施可以改善医院到家庭的过渡护理。有效的干预措施包括家访,ICT,案例管理器模型,多学科团队,和自我管理支持。人们发现,由于人力资源不足等背景因素,这些干预措施在苏丹的实施受到损害,电信不稳定,和可访问性的不平等。这些干预措施可以根据对低收入国家影响实施的背景因素的深入了解来调整。
    https://osf.io/9eqvr/,doi:10.17605/OSF.IO/9EQVR。
    UNASSIGNED: Hospital discharge is often associated with a lack of continuity resulting in fragmented care, particularly in low-income countries. As there is limited information about interventions in these countries and no study evaluating the effectiveness of hospital discharge interventions, we conducted a scoping review to identify effective hospital-to-home transitional care interventions and explore their applicability in a low-income country (Sudan).
    UNASSIGNED: Our scoping review of systematic reviews and meta-analyses classed interventions as effective, ineffective, undesirable, or uncertain, based on the quality of their evidence and their estimated effects on the following outcomes: readmission rates, mortality, costs, quality of life, and adverse outcomes) and certainty of evidence. Our authors from Sudan used the SUPPORT summary tool to determine if three effective interventions could be implemented in Sudan.
    UNASSIGNED: Out of 3,276 articles that were identified, and 72 articles were reviewed, 10 articles has been included in the review. Seven interventions were classified as effective, one as ineffective, and none with undesirable effects. Eight interventions were classified as having an uncertain effect. The effective interventions were composed of home visits, information and communication technology (ICT), case manager models, multidisciplinary teams, and self-management support.
    UNASSIGNED: The finding of this study suggested that a combining two to four interventions can improve enhance hospital-to-home transitional care. Effective interventions are composed of home visits, ICT, case manager models, multidisciplinary teams, and self-management support. The implementation of these interventions in Sudan was found to be undermined by contextual factors such as inadequate human resources, telecommunication instability, and inequality in accessibility. These interventions could be tailored based on an in-depth understanding of the contextual factors in low-income countries that influence implementation.
    UNASSIGNED: https://osf.io/9eqvr/, doi: 10.17605/OSF.IO/9EQVR.
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  • 文章类型: Journal Article
    背景:既往有跌倒史导致髋部骨折的老年人很难恢复骨折前的功能。科学证据表明,实施多维康复计划有好处,但就出院后的护理连续性而言,这一证据并未系统化.
    目的:确定促进老年人髋部骨折出院后安全性和功能恢复的干预措施。
    方法:根据Cochrane方法进行系统评价。研究策略是针对MEDLINE和CINAHL数据库预定义的。由两名独立审稿人根据资格标准筛选鉴定的文章。对书目样本中的文章进行了偏倚风险评估。
    结果:在发现的10,036篇文章中,本系统综述中包括10个。确定的促进安全的干预措施是:运动培训,职业治疗/日常生活培训活动,转移和步态训练,加强练习,辅助器具使用教育,跌倒预防教育,营养评估,在家中进行环境修改/调整,使用一个应用程序,药物,自我保健教育,支持和咨询。
    结论:在分析的8项研究中,运动训练是促进老年人髋部骨折后回家安全的最有效干预措施.三项研究将两种或两种以上的干预措施联系在一起,专注于运动训练,职业治疗/日常生活活动培训,以及常规的术后康复,包括转移和步态训练,加强练习,辅助设备使用和排放规划教育,旨在实现肌肉强化和安全步态,与日常生活活动的表现有关。
    BACKGROUND: Older adults with a prior history of falls that results in hip fractures have difficulties in regaining pre-fracture functional capacity. Scientific evidence has shown benefits of the implementation of multidimensional rehabilitation programs, but this evidence is not systematized with regard to continuity of care after hospital discharge.
    OBJECTIVE: To identify interventions that promote safety and functional recovery of older adults with hip fractures after hospital discharge.
    METHODS: A systematic review was carried out according to Cochrane methodology. The research strategy was predefined for the MEDLINE and CINAHL databases. The identified articles were screened according to the eligibility criteria by two independent reviewers. The articles included in the bibliographic sample were evaluated for risk of bias.
    RESULTS: Of the 10,036 articles found, 10 were included in this systematic review. The safety-promoting interventions identified were: exercise training, occupational therapy/activities of daily living training, transfer and gait training, strengthening exercises, education on assistive device use, fall prevention education, nutritional assessment, environmental modifications/adjustments at home, use of an app, medication, self-care education, and support and counseling.
    CONCLUSIONS: In eight studies analyzed, exercise training emerged as the most effective intervention for promoting the safety of older adults after hip fractures on returning home. Three studies associated two or more interventions, which focused on exercise training, occupational therapy/training of activities of daily living, and conventional postoperative rehabilitation with transfer and gait training, strengthening exercises, education on assistive device use and discharge planning, aiming to achieve muscle strengthening and safe gait, associated with the performance of activities of daily living.
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  • 文章类型: Journal Article
    背景:出院药物审查(DMR)是威尔士的一项社区药房服务,旨在减少护理过渡后与药物相关的伤害,包括出院.要进行DMR,社区药剂师必须接收患者的出院药物信息,无论是电子,通过传真或由患者出示。尽管DMR已经证明了改善患者安全的好处,它的评估显示吸收不一致,社区药剂师部分归因于医院没有提供必要的信息。
    目标:旨在提出建议,以提高医院对DMR转诊的参与度,本研究探讨了医院药学专业人员对该服务的看法。
    方法:定性焦点小组,使用解释学现象学,在威尔士的16家医院进行,使用配额抽样方法,包括61名药剂师和31名药房技术员。要了解对DMR推荐的次优参与,使用实施研究综合框架(CFIR)进行了框架分析。
    结果:数据被映射到所有五个CFIR域,每个都包含参与DMR推荐和改进建议的障碍和促进者。只有一家医院成功实施了DMR转诊,许多参与者缺乏对服务的任何了解或如何引用它。具体障碍包括明显缺乏实施转诊和聘请医院药学专业人员的流程。一个相当大的障碍是许多参与者认为社区药剂师的角色不如他们自己的角色以临床为导向和以患者为中心,把他们看作是一个不同的职业。参与者认为,DMR推荐的本地冠军可以促进参与并将其整合到医院药学专业人员的工作流程中。改善参与的进一步建议是对DMR的员工培训以及对其价值的定期反馈。
    结论:政策制定者可以利用这项研究的发现和建议,促进医院药房工作人员参与类似的社区药房服务,如英国的出院药物服务。
    BACKGROUND: The Discharge Medicines Review (DMR) is a community pharmacy service in Wales that aims to reduce medicines-related harm after care transitions, including hospital discharge. To undertake a DMR, the Community Pharmacist must receive a patient\'s discharge medicines information, either electronically, by fax or presented by the patient. Although the DMR has evidenced benefits for improving patient safety, its evaluation showed inconsistent uptake, which Community Pharmacists partially attributed to hospitals not providing the necessary information.
    OBJECTIVE: Aiming to develop recommendations to improve hospital engagement to DMR referrals, this study explores hospital pharmacy professionals\' views of the service.
    METHODS: Qualitative focus groups, using hermeneutic phenomenology, were conducted in 16 hospitals across Wales, using a quota sampling method to include 61 Pharmacists and 31 Pharmacy Technicians. To understand the suboptimal engagement to DMR referrals, framework analysis was undertaken using the Consolidated Framework for Implementation Research (CFIR).
    RESULTS: The data were mapped onto all five CFIR domains, each containing barriers and facilitators to engagement with DMR referrals and suggestions for improvement. Only one hospital had successfully implemented DMR referrals, with many participants lacking any knowledge of the service or how to refer to it. Specific barriers included a clear absence of processes to implement referrals and engage hospital pharmacy professionals. A considerable barrier was many participants\' perceptions that Community Pharmacist roles were less clinically orientated and patient-centred than their own, viewing them almost as a different profession. Participants believed that local champions for DMR referrals could promote engagement and integrate them into the workflow of hospital pharmacy professionals. Further recommendations to improve engagement was staff training for DMRs and regular feedback of its value.
    CONCLUSIONS: Policymakers may use the findings and recommendations from this study to promote hospital pharmacy staff engagement to similar community pharmacy services like the Discharge Medicines Service in England.
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  • 文章类型: Meta-Analysis
    背景:在极早产儿和中度至晚期早产儿中,单独使用按摩疗法或与被动活动疗法一起使用对体重增加和住院时间的影响尚待阐明。
    目的:比较单纯按摩或联合被动活动与对照组早产儿的治疗效果。
    方法:根据系统评价和荟萃分析报表的首选报告项目进行系统评价和荟萃分析。纳入了在早产儿中比较单独按摩或结合被动动员与对照组的随机对照试验。MEDLINE,EMBASE,恩菲斯波,PEDro和Cochrane数据库在2022年3月之前进行了搜索。
    方法:早产儿。
    方法:体重增加和住院时间。
    结果:与常规护理相比,按摩疗法联合被动活动被证明在改善体重增加(标准化平均差[95CI]0.67[0.31,1.02])和缩短住院时间(0.53[0.10,0.97])方面更有效.然而,单纯的按摩疗法并不能有效改善体重增加(1.14[-0.22,2.49]).根据孕龄,两组之间的这些疗法的有效性没有差异(p>0.05)。
    结论:基于公平到高质量的证据,按摩疗法结合被动活动可显著改善早产儿的体重增加并缩短住院时间.然而,单靠按摩疗法并不能实现这些改善。
    The effect of massage therapy alone or together with passive mobilisations on weight gain and length of hospitalisation in very preterm and moderate-to-late preterm infants remains to be elucidated.
    To compare massage therapy alone or combined with passive mobilisations with a control group in preterm infants.
    A systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was conducted. Randomised controlled trials comparing massage therapy alone or combined with passive mobilisations with a control group in preterm infants were included. MEDLINE, EMBASE, ENFISPO, PEDro and Cochrane databases were searched up to March 2022.
    Preterm infants.
    Weight gain and time of hospitalisation.
    Compared to usual care, massage therapy combined with passive mobilisations was demonstrated to be more effective in improving weight gain (standardized mean difference [95%CI] 0.67 [0.31, 1.02]) and reducing length of hospitalisation (0.53 [0.10, 0.97]) outcomes. However, massage therapy alone was not effective in improving weight gain (1.14 [-0.22, 2.49]). No differences in the effectiveness of these therapies between groups according to gestational age were found (p > 0.05).
    Based on fair-to-high quality evidence, massage therapy combined with passive mobilisations significantly improves weight gain and reduces length of hospitalisation in premature infants. However, massage therapy alone does not achieve these improvements.
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  • 文章类型: Journal Article
    回顾有关单峰感觉运动刺激方案对极早产儿和中度至晚期早产儿(PIs)喂养结果影响的文献。
    截至2022年4月,共搜索了5个数据库。比较基于手动口腔刺激与NNS结合的单峰感觉运动刺激方案与PI常规护理的研究,按时过渡到完全口服喂养(FOF),喂养功效,住院时间,和/或体重增加。
    包括11项研究。与常规护理相比,基于手动口腔刺激结合NNS的单峰感觉运动刺激方案被证明在减少到FOF的时间过渡方面更有效(标准化平均差[95CI]-1.08[-1.74,-0.41]),改善喂养效率(2.15[1.18,3.13])和缩短住院时间(-0.35[-0.68,-0.03])。然而,建议的干预措施对改善体重增加没有效果(0.27[-0.40,0.95]).根据胎龄差异无统计学意义(p>.05)。
    基于公平到高质量的证据,单峰感觉运动刺激方案结合NNS减少了向FOF的时间过渡,提高喂养功效,并缩短住院时间;然而,与PI的常规护理相比,拟议的干预措施对体重增加没有显著影响。
    To review the literature on the effects of unimodal sensorimotor stimulation protocols on feeding outcomes in very preterm and moderate to late preterm infants (PIs).
    Five databases were searched up to April 2022. Studies comparing unimodal sensorimotor stimulation protocols based on the combination of manual oral stimulation with NNS against usual care in PIs, on-time transition to full oral feeding (FOF), feeding efficacy, length of hospital stay, and/or body weight gain.
    Eleven studies were included. Compared to usual care, unimodal sensorimotor stimulation protocols based on manual oral stimulation combined with NNS demonstrated to be more effective in decreasing time transition to FOF (standardized mean difference [95%CI] - 1.08 [-1.74, -0.41]), improving feeding efficacy (2.15 [1.18, 3.13]) and shortening length of hospital stay (-0.35 [-0.68, -0.03]). However, the proposed intervention was not effective in improving weight gain (0.27 [-0.40, 0.95]). There were no significant differences according to gestational age (p > .05).
    Based on fair-to-high quality evidence, unimodal sensorimotor stimulation protocols combined with NNS reduce time transition to FOF, improve feeding efficacy, and shorten the length of hospital stay; yet the proposed intervention yielded no significant effects on body weight gain when compared to usual care in PIs.
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  • 文章类型: Journal Article
    背景:随着技术采用的增加,数字健康干预措施在医疗机构中的使用有所增加。患者-临床医生数字健康干预有可能改善患者护理,尤其是在医院和家庭之间的重要过渡期间。数字健康干预可以在这些转变期间为患者提供支持,从而导致更好的患者结果。
    目的:本范围综述旨在探索现有文献,特别是(1)检查基于平台的数字健康干预措施对患者预后的影响,(2)确定采用和实施这些数字卫生干预措施的障碍和促成因素。
    方法:该协议是基于Arksey和O\'Malley's开发的,Levac和同事们,和JBI范围审查方法,并且已根据PRISMA-ScR(用于系统审查的首选报告项目和用于范围审查的荟萃分析声明)格式进行报告。为4个数据库开发了搜索策略:MEDLINE,CINAHL,EMBASE,以及Cochrane中央受控试验登记册,使用“医院到家庭过渡”和“基于平台的数字健康”等关键词。本综述将包括涉及16岁或以上患者在医院到家庭过渡期间使用基于平台的数字健康干预的研究。两名审阅者将通过使用2阶段流程独立筛选文章的资格(即,标题和摘要筛选和全文筛选)。我们希望在标题和摘要筛选过程中完善资格标准,因为我们预计会检索大量文章。此外,我们还将对灰色文献进行有针对性的搜索,以及数据提取。数据分析将包括叙述和描述性综合。
    结果:该综述预计将发现研究空白,为未来患者-临床医生数字健康干预措施的发展提供信息。我们共确定了8333篇文章。筛查于2022年9月开始,数据提取预计将于2023年2月开始,至2023年4月结束。数据分析和最终结果将于2023年8月提交给同行评审的期刊。
    结论:我们希望找到各种各样的护理干预措施,研究证据质量方面的一些差距,以及缺乏有关数字健康干预措施的详细信息。
    PRR1-10.2196/42056。
    BACKGROUND: With the increased adoption of technology, the use of digital health interventions in health care settings has increased. Patient-clinician digital health interventions have the potential to improve patient care, especially during important transitions between hospital and home. Digital health interventions can provide support to patients during these transitions, thereby leading to better patient outcomes.
    OBJECTIVE: This scoping review aims to explore the available literature, specifically (1) to examine the impact of platform-based digital health interventions focused on care transitions on patient outcomes, and (2) to identify the barriers to and enablers for the uptake and implementation of these digital health interventions.
    METHODS: This protocol was developed based on Arksey and O\'Malley\'s, Levac and colleagues\', and JBI scoping review methodologies, and it has been reported according to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement for the Scoping Reviews) format. The search strategies were developed for 4 databases: MEDLINE, CINAHL, EMBASE, and the Cochrane Central Register of Controlled Trials by using key words such as \"hospital to home transition\" and \"platform-based digital health.\" Studies involving patients 16 years or older that used a platform-based digital health intervention during their hospital to home transition will be included in this review. Two reviewers will independently screen articles for eligibility by using a 2-stage process (ie, title and abstract screening and full-text screening). We expect to refine the eligibility criteria during the title and abstract screening process as we anticipate retrieving a significant number of articles. In addition, we will also perform a targeted search of the grey literature, as well as data extraction. Data analysis will consist of a narrative and descriptive synthesis.
    RESULTS: The review is expected to identify research gaps that will inform the development of future patient-clinician digital health interventions. We have identified a total of 8333 articles. Screening began in September 2022, and data extraction is expected to commence in February 2023 and end by April 2023. Data analyses and final results will be submitted to a peer-reviewed journal in August 2023.
    CONCLUSIONS: We expect to find a wide variety of postcare interventions, some gaps in the quality of research evidence, as well as a lack of detailed information on digital health interventions.
    UNASSIGNED: PRR1-10.2196/42056.
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  • 文章类型: Observational Study
    背景:出院时不适当的抗生素处方已被认为是一个重大问题。尽管抗生素处方错误率很高,没有广泛接受的抗菌药物管理计划来防止此类错误。
    目的:本研究的主要目的是确定以医院为基础的临床药师出院处方审查对抗生素处方适当性的影响。
    方法:这是一项观察性研究,比较了两种类似内科服务之间出院抗生素处方的适当性。一组患者被纳入药物服务,其中四舍五入的临床药师进行常规抗生素出院评估,比较队列在没有常规药剂师出院抗生素审查的情况下接受了住院医师服务.
    结果:我们的研究包括每个队列150例。组间基线特征相似,除了年龄增加(p=0.025)和急性细菌性皮肤和皮肤结构感染的病例减少(p=0.001)。药物(药剂师)组的抗生素适当性明显高于住院医师组[(83%对54%,分别(p<0.00001)]。适当性的差异主要是由肺炎和尿路感染处方引起的。
    结论:在药师出院审查的设置中,抗生素处方的适当性显著提高。这一举措突出了临床药师在门诊抗菌药物管理中的重要作用。
    BACKGROUND: Inappropriate antibiotic prescribing upon hospital discharge has been identified as a significant problem. Despite high rates of antibiotic prescription errors, there is no widely accepted antimicrobial stewardship initiative to prevent such errors.
    OBJECTIVE: The primary objective of this study was to determine the impact of hospital-based clinical pharmacist discharge prescription review on the appropriateness of antibiotic prescriptions.
    METHODS: This was an observational study comparing the appropriateness of hospital discharge antibiotic prescriptions between two similar internal medicine services. One cohort of patients was admitted to medicine services where rounding clinical pharmacists performed routine antibiotic discharge assessment, and the comparator cohort was admitted to hospitalist services without routine pharmacist discharge antibiotic review.
    RESULTS: Our study included 150 cases per cohort. Baseline characteristics were similar between groups, except for increased age (p = 0.025) and fewer cases of acute bacterial skin & skin structure infections (p = 0.001) in the hospitalist cohort. Antibiotic appropriateness was considerably greater in the medicine (pharmacist) group versus hospitalist group [(83% versus 54%, respectively (p < 0.00001)]. The difference in appropriateness was mainly driven by pneumonia and urinary tract infection prescriptions.
    CONCLUSIONS: Appropriateness of antibiotic prescriptions significantly improved in the setting of pharmacist discharge review. This initiative highlights the important role of clinical pharmacists in outpatient antimicrobial stewardship.
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  • 文章类型: Journal Article
    与肌肉和骨骼质量减少相关的衰老和身体虚弱导致老年人的脆弱性和跌倒风险增加。据估计,在这个年龄组中,每十个跌倒中就有一个会导致骨折,导致他们的健康状况螺旋式下降,造成更大的依赖,功能逐渐下降,这使得骨折前难以恢复其功能和社会地位。这项研究的目的是确定有关干预措施的可用证据,以促进出院后老年人髋部骨折的安全性。将在MEDLINE和CINAHL数据库中进行搜索。以功能评估为重点的随机对照研究,在日常生活活动中的表现,对跌倒的关注程度,跌倒的风险和患病率,受伤继发于跌倒,将包括髋部骨折患者的再骨折率和与健康相关的生活质量。两位作者将进行研究选择,数据提取,独立进行质量评估。任何分歧都将通过与第三位研究人员的讨论来解决。纳入试验的方法学质量将通过Cochrane偏见风险标准进行评估。和控制试验中干预措施的报告标准。
    Ageing and physical frailty associated with decrease in muscle and bone mass lead to the older persons\' vulnerability and increased risk of falling. It is estimated that one in every ten falls in this age group results in a fracture, leading to a downward spiral in their health status, causing greater dependence, with a progressive functional decline that makes it difficult to return to their functional and social status prior to the fracture. The aim of this study is to identify the available evidence on the interventions that promote the safety of older people with hip fracture after hospital discharge. A search will be performed in MEDLINE and CINAHL databases. Randomised and controlled studies that focus on functional assessment, performance in activities of daily living, level of concern about falls, risk and prevalence of falls, injuries secondary to falls, re-fracture rate and health-related quality of life in hip fracture patients will be included. Two authors will perform the study selection, data extraction, and quality assessment independently. Any disagreements will be resolved through discussion with a third researcher. Methodological quality of the included trials will be evaluated by the Cochrane risk-of-bias criteria, and the Standards for Reporting Interventions in Controlled Trials.
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