Zebrafish are one of the most used animal models in biological research and a cost-effective alternative to rodents. Despite this, nutritional requirements and standardized feeding protocols have not yet been established for this species. This is important to avoid nutritional effects on experimental outcomes, and especially when zebrafish models are used in preclinical studies, as many diseases have nutritional confounding factors. A key aspect of zebrafish nutrition is related to feed intake, the amount of feed ingested by each fish daily. With the goal of standardizing feeding protocols among the zebrafish community, this paper systematically reviews the available data from 73 studies on zebrafish feed intake, feeding regimes (levels), and diet composition. Great variability was observed regarding diet composition, especially regarding crude protein (mean 44.98 ± 9.87%) and lipid content (9.91 ± 5.40%). Interestingly, the gross energy levels of the zebrafish diets were similar across the reviewed studies (20.39 ± 2.10 kilojoules/g of feed). In most of the reviewed papers, fish received a predetermined quantity of feed (feed supplied). The authors fed the fish according to the voluntary intake and then calculated feed intake (FI) in only 17 papers. From a quantitative point of view, FI was higher than when a fixed quantity (pre-defined) of feed was supplied. Also, the literature showed that many biotic and abiotic factors may affect zebrafish FI. Finally, based on the FI data gathered from the literature, a new feeding protocol is proposed. In summary, a daily feeding rate of 9-10% of body weight is proposed for larvae, whereas these values are equal to 6-8% for juveniles and 5% for adults when a dry feed with a proper protein and energy content is used.

With the growing global demand for animal protein and rising temperatures caused by climate change, heat stress (HS) is one of the main emerging environmental challenges for the poultry industry. Commercially-reared birds are particularly sensitive to hot temperatures, so adopting production systems that mitigate the adverse effects of HS on bird performance is essential and requires a holistic approach. Feeding and nutrition can play important roles in limiting the heat load on birds; therefore, this review aims to describe the effects of HS on feed intake (FI) and nutrient digestibility and to highlight feeding strategies and nutritional solutions to potentially mitigate some of the deleterious effects of HS on broiler chickens. The reduction of FI is one of the main behavioral changes induced by hot temperatures as birds attempt to limit heat production associated with the digestion, absorption, and metabolism of nutrients. Although the intensity and length of the heat period influences the type and magnitude of responses, reduced FI explains most of the performance degradation observed in HS broilers, while reduced nutrient digestibility appears to only explain a small proportion of impaired feed efficiency following HS. Targeted feeding strategies, including feed restriction and withdrawal, dual feeding, and wet feeding, have showed some promising results under hot temperatures, but these can be difficult to implement in intensive rearing systems. Concerning diet composition, feeding increased nutrient and energy diets can potentially compensate for decreased FI during HS. Indeed, high energy and high crude protein diets have both been shown to improve bird performance under HS conditions. Specifically, positive results may be obtained with increased added fat concentrations since lipids have a lower thermogenic effect compared to proteins and carbohydrates. Moreover, increased supplementation of some essential amino acids can help support increased amino acid requirements for maintenance functions caused by HS. Further research to better characterize and advance these nutritional strategies will help establish economically viable solutions to enhance productivity, health, welfare, and meat quality of broilers facing HS.

Low feed consumption during the first 3 d post-weaning disrupts nutrient intake and results in what is commonly known as a post-weaning growth check. While most pigs recover from this initial reduction in feed intake (FI), some pigs fail to successfully make this transition leading to morbidity and mortality. In this review, our objective is to describe the different post-weaning strategies that can be used to minimize nutrient intake disruption and improve FI in the immediate post-weaning period. Providing weanling pigs with an environment that encourages them to search out and consume feed is important. This includes appropriate barn temperatures, resource availability, and nursery placement strategies. Research is needed to better understand the ideal environmental temperatures to encourage pen exploration and reduce time to initial FI. Likewise, mat and gruel feeding are commonly practiced throughout the industry to increase feed accessibility; however, limited research data is available to validate protocols or benefits. Nursery placement strategies include sorting light weight pigs into uniform body weight groups and average or heavy weight pigs into variable body weight groups to provide benefit to light pigs while reducing initial aggression in heavy pigs. Furthermore, water enrichment with nutrient dense products have been shown to improve growth performance and reduce morbidity and mortality in the early post-weaning period. Because young pigs are sensitive to palatability, diet form and complexity should also be considered. Weanling pigs prefer diets manufactured with coarse ground corn (700 μm) compared to fine ground corn. Additionally, weanling pigs are more attracted to large diameter pellets (12 mm) compared with small pellets. Despite these preferences, impacts on growth are relatively small. Feeding complex diets with high levels of lactose, animal protein products, or other palatable ingredients is another strategy shown to improve growth performance during the first week post-weaning; however, the initial benefits quickly diminished as pigs become older. Other strategies that warrant further investigation include the effect of crumble diets on feed preference and the concept of perinatal or social interaction flavor learning. In summary, strategic post-weaning nutrition and management practices must focus on maintaining continuity of nutrient intake in order to reduce morbidity and mortality in the immediate post-weaning period.

Weaning is a crucial phase of swine production marked by a multitude of biological and environmental stressors, which have a significant impact on immediate postweaning behavior and feed intake (FI). During this time, the piglet\'s gastrointestinal (GI) system is also undergoing extensive epithelial, immune, and nervous system development. In this review, our objective is to describe the different preweaning strategies that can be used to minimize nutrient intake disruption and improve FI in the immediate postweaning period. Reducing nutrient disruption postweaning can be accomplished through the implementation of management and nutritional strategies. Research consistently demonstrates that weaning older, more developmentally mature pigs helps prevent many of the adverse GI effects associated with weaning stress. Providing creep feed to pigs during lactation is another reliable strategy that has been shown to increase immediate postweaning FI by acclimating pigs to solid feed prior to weaning. Likewise, socialization by allowing pigs to mix before weaning improves social skills, minimizing mixing stress, and aggression-related injury immediately postweaning. Supplemental milk replacer has also been shown to elicit a positive response in preweaning growth performance, which may help to reduce preweaning mortality. While socialization and milk replacer are acknowledged to ease the weaning transition, these strategies have not been widely adopted due to labor and application challenges. Additionally, the cost of milk replacer and logistics of retrofitting farrowing houses to accommodate litter socialization have limited adaptation. Further exploration of maternal nutrition strategies, particularly fetal imprinting, is needed to better understand the implications of perinatal learning. Other areas for future research include, combining environmental enrichment with feeding strategies, such as large destructible pellets or play feeders, as well as determining at what time point producers should start socializing pigs before weaning. While more research is needed to develop strategic preweaning management programs, many of the strategies presented in this review provide opportunities for producers to minimize nutrient intake disruption by preventing feed neophobia, reducing stress, and easing the wean pig transition.

Heat stress (HS) is a major problem in poultry business which affects chickens\' performance and may trigger large economic losses. This study intends to analyze the impact of HS on broiler chickens\' performance compared with those under normal condition. A literature search was performed on PubMed, Web of Science, and Cochrane Library for studies published in English up to January 17, 2020. Outcomes of body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR), and mortality were calculated by weighted difference (WMD) or odds ratio (OR) with 95% confidence interval (CI). A total of 12 studies with 470 broiler chickens were included. HS significantly decreased FI (11 trials: WMD = -97.95, 95% CI: -141.70, -54.20) and BWG (7 trials: WMD = -151.40, 95% CI: -198.59, -104.21) and significantly increased FCR (9 trials: WMD = 0.17, 95% CI: 0.04, 0.29) and mortality (8 trials: OR = 3.74, 95% CI: 1.39, 10.12) compared with the control. In conclusion, HS significantly affected broiler chickens\' BWG, FI, FCR, and mortality, indicating the importance to control housing temperature to avoid unnecessary costs.

The California Net Energy System (CNES) can reliably project performance of feedlot cattle based on three factors: expected dry matter intake (DMI), some index of degree of maturity of cattle linked to body composition (fat and protein content), and an estimate of the net energy (NE) content of the diet. The CNES allowed feedlot managers to monitor growth and efficiency of individual pens of cattle. Through assigning distinct values for net energy for maintenance (NEm) vs. net energy for gain (NEg) of the metabolizable energy (ME) present in feeds, the CNES enables valid economic comparisons among feedstuffs, an appraisal not feasible based on total digestible nutrients or digestible energy (DE) values. Because NEm and NEg are linked mathematically to ME, the CNES also allows performance-adjusted ME (paME) value of diets to be calculated from observed DMI and growth or carcass measurements. Compared with other productivity measures (e.g., average daily gain and gain-to-feed ratio) that are confounded with and affected by DMI, the CNES logically separates production responses by cattle into two factors-DMI and ME of the diet. This enables research scientists or cattle producers to appraise responses within these two factors independently. In feeding studies, means of paME values were related closely to ME values of diets calculated from the ME of diet ingredients. But unlike ME values projected from diet analyses, paME estimates are affected by environmental conditions (e.g., season, weather, animal interactions, stress, nutritional history and deficiencies, associative effects of feeds, imprecise feed management, and animal healthfulness and disorders). These factors typically overestimate ME intake or increase energy requirements, both of which decrease energetic efficiency. By comparing paME with ME values calculated from diet composition, logical reasons behind performance responses to and quantitative benefits from feed additives, grain processing, hormone implants, and animal management can be appraised. Considering the evolution in cattle types, management and marketing conditions, and changes in diet ingredients and processing that have occurred during the past 50 yr, updating by a skilled committee to correct certain anomalies within the CNES as currently being applied seems appropriate. Developing simplified spreadsheets could help users evaluate their own dietary and management conditions and assure that the CNES continues to be widely applied by the feedlot industry within the United States and worldwide.

Feeding environment and feed accessibility influence the dairy cow\'s response to the ration and forage composition. Fiber content, physical form, and fermentability influence feeding behavior, feed intake, and overall cow metabolic and lactational responses to forage. It is possible to vary eating time of lactating dairy cattle by over 1 h/d by changing dietary silage fiber content, digestibility, and particle size. Optimizing silage particle size is important because excessively long particles increase the necessary chewing to swallow a bolus of feed, thereby increasing eating time. Under competitive feeding situations, excessively coarse or lower fiber digestibility silages may limit DMI of lactating dairy cows due to eating time requirements that exceed available time at the feed bunk. Additionally, greater silage particle size, especially the particles retained on the 19-mm sieve using the Penn State Particle Separator, are most likely to be sorted. Silage starch content and fermentability may influence ruminal propionate production and thereby exert substantial control over meal patterns and feed consumption. Compared with silage fiber characteristics, relatively little research has assessed how silage starch content and fermentability interact with the feeding environment to influence dairy cow feeding behavior. Finally, voluminous literature exists on the potential effects that silage fermentation end products have on feeding behavior and feed intake. However, the specific mechanisms of how these end products influence behavior and intake are poorly understood in some cases. The compounds shown to have the greatest effect on feeding behavior are lactate, acetate, propionate, butyrate, ammonia-N, and amines. Any limitation in the feeding environment will likely accentuate the negative response to poor silage fermentation. In the future, to optimize feeding behavior and dry matter intake of silage-based diets fed to dairy cattle, we will need to consider the chemical and physical properties of silage, end products of silage fermentation, and the social and physical components of the feeding environment.

Genetic selection that has been carried out for several dozen years has led to significant progress in poultry production by improving productive traits and increasing the profitability of broiler breeder and layer hen production. After hatching, broilers and layers differ mainly in feed intake, growth rate, efficiency of nutrient utilization, and development of muscles and adipose tissue. A key role can be played by hormonal mechanisms of appetite control in broilers and layers. The paper discusses the consequences of different growth rates resulting from long-term genetic selection on feed intake, efficiency of nutrient utilization, and development of muscles and adipose tissue, with particular consideration of the hormonal mechanisms of appetite control in broilers and layers. The information presented in this review paper shows that it would be worth comparing these issues in a meta-analysis.