马疱疹病毒1(EHV-1)是一种高度流行且经常致病的马科动物感染。感染最严重的临床后果是流产和马疱疹病毒性脊髓脑病(EHM)。先前的共识声明于2009年发表,并考虑了发病机理,应变变化,流行病学,诊断测试,疫苗接种,疫情防控,和治疗。最近对美国兽医内科学院大型动物文凭的一项调查发现,有必要对这一原始共识声明进行修订。这份最新的共识声明以4项系统审查为基础,这些审查涉及疫苗接种的关键问题。药物治疗,发病机制,和诊断测试。成功接种疫苗的证据,或EHV-1感染的有效治疗是有限的,在未来对这种重要疾病的研究中,需要改进实验设计和结果报告。这份协商一致声明还更新了2009年以前审议的议题。
Equine herpesvirus-1 (EHV-1) is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). The previous
consensus statement was published in 2009 and considered pathogenesis, strain variation, epidemiology, diagnostic testing, vaccination, outbreak prevention and control, and treatment. A recent survey of American College of Veterinary Internal Medicine large animal diplomates identified the need for a revision to this original
consensus statement. This updated
consensus statement is underpinned by 4 systematic reviews that addressed key questions concerning vaccination, pharmaceutical treatment, pathogenesis, and diagnostic testing. Evidence for successful vaccination against, or effective treatment of EHV-1 infection was limited, and improvements in experimental design and reporting of results are needed in future studies of this important disease. This
consensus statement also updates the topics considered previously in 2009.