目的:种植体周围炎治疗的主要斗争是成功清除受感染的种植体表面。这项研究的主要假设是Er,Cr:YSGG激光净化效果研究感染的植入物表面具有各种植入物周围炎缺陷。这项研究的主要目的是确定Er的疗效,Cr:YSGG激光作为各种种植体周围炎模拟缺陷的去污工具。次要目标是比较Er的功效,Cr:YSGG激光在两种方案之间的口腔生物膜去除,第一种方案(2.5分钟时4个周期)和第二种方案(5分钟时5个周期)在各种种植体周围炎模拟缺陷。
方法:将在24个测试植入物上体内形成斑块生物膜的总共3名受试者分成4个测试组。测试两种天然植入物作为对照。体外缺损模型是计算机辅助设计的,并打印到3D打印模型中,在种植体周围缺损中进行各种处理,分别为15,30,60和90度。
结果:两者,Cr:50mJ(1.5W/30Hz)的YSGG净化方案,50%空气,和40%的水有效地减少了植入物的总表面积/生物膜比率(%),但与第一个方案(4个周期,2.5分钟)相比,第二个方案的应用持续时间(5个周期,5分钟)明显缩短.
结论:Er,Cr:YSGG激光是各种种植体周围炎缺陷的有效去污装置。具有更长的应用时间和循环的第二方案(5分钟的5个循环)比第一方案更有效。缺陷角度影响种植体周围炎治疗的去污能力。
■临床医生预计,由于文献中现有证据的明显异质性以及需要建立临床前理论基础,因此对种植体周围炎治疗的合适治疗方式的探索受到限制。与种植体周围炎治疗相关的主要挑战包括成功净化受感染的种植体表面,对具有足够表面粗糙度的处理过的植入物表面没有任何损伤,和植入物表面的生物相容性,这允许成骨细胞在治疗表面生长,是成功的骨整合的关键。因此,这些是预期的经验三合会,需要尊重成功的种植体周围炎治疗。其中一个三联征的失败代表种植体周围炎治疗失败。Er,Cr:YSGG激光器被认为是实现所需三元组的预期装置之一。
背景:\“Er的功效,CrYSGG激光治疗种植体周围炎。
结果:政府IDNCT05137821。首次发布日期:2021年11月30日。
OBJECTIVE: The major struggle in peri-implantitis therapy is the availability of successful decontamination of the infected implant surface. The main hypothesis of this study was the Er,Cr: YSGG laser decontamination efficacy investigation on the infected implant surfaces with various peri-implantitis defects. The primary objective of this study was to decide the efficacy of Er,Cr:YSGG laser as a decontamination tool at various peri-implantitis simulating defects. The secondary objective was to compare the efficacy of the Er,Cr: YSGG laser on oral biofilm removal between two protocols the first protocol (4 cycles at 2.5 min) and the second protocol (5 cycles at 5 min) at various peri-implantitis simulating defects.
METHODS: A total of 3 subjects whose plaque biofilms formed in-vivo on twenty-four tested implants were divided into four tested groups. Two native implants were tested as controls.The in vitro defect model was computer-aided designed and printed into a 3D-printed model with various anulations in peri-implant infrabony defects, which were 15,30,60,and 90 degrees.
RESULTS: Both Er, Cr: YSGG decontamination protocols at 50 mJ (1.5 W/30 Hz), 50% air, and 40% water were effective at reducing the total implant surface area/ biofilm ratio (%), but the second protocol had a markedly greater reduction in the duration of application (5 cycles at 5 min) than did the first protocol (4 cycles at 2.5 min).
CONCLUSIONS: The Er, Cr: YSGG laser is an effective decontamination device in various peri-implantitis defects. The second protocol(5 cycles at 5 min) with greater application time and circles is more effective than the first one. The defect angulation influence the decontamination capability in peri-implantitis therapy.
UNASSIGNED: Clinicians anticipate that the exploration of suitable therapeutic modalities for peri-implantitis therapy is limited by the obvious heterogeneity of the available evidence in the literature and need for a pre-clinical theoretical basis setup. The major challenges associated with peri-implantitis therapy include the successful decontamination of the infected implant surface, the absence of any damage to the treated implant surface with adequate surface roughness, and the biocompatibility of the implant surface, which allows osteoblastic cells to grow on the treated surface and is the key for successful re-osseointegration. Therefore, these are the expected empirical triads that need to be respected for successful peri-implantitis therapy. Failure of one of the triads represents a peri-implantitis therapeutic failure. The Er, Cr: YSGG laser is regarded as one of the expected devices for achieving the required triad.
BACKGROUND: \"Efficacy of Er,Cr YSGG Laser in Treatment of Peri-implantitis\".
RESULTS: gov ID NCT05137821. First Posted date: 30 -11-2021.