deep

  • 文章类型: Case Reports
    我们在此报告一例发育性静脉异常(DVA),由颅内出血(ICH)的集合静脉狭窄引起的静脉充血。一名74岁的妇女在运动性失语症发作后几天被转诊到我们医院。计算机断层扫描(CT)和磁共振成像(MRI)显示左额叶ICH。血管造影显示静脉晚期左额叶DVA。检测到上矢状窦入口处的DVA收集静脉狭窄,并伴有DVA旁边的海绵状畸形(CM)。锥形束CT显示不存在左间隔静脉和发育不良的横向尾状静脉。患者接受血压管理治疗,未检测到其他神经系统症状。DVA的发展是为了弥补静脉或深静脉系统的缺失,一般是良性的,临床上无症状。然而,DVA的流出限制导致慢性静脉高压和CM的形成。这些异常被认为发生在产后生活中,并可能导致ICH。对于静脉流出受限或CM的DVA,需要考虑出血的风险。
    We herein report a case of developmental venous anomaly (DVA) with venous congestion caused by stenosis of the collecting vein that presented with intracerebral hemorrhage (ICH). A 74-year-old woman was referred to our hospital a few days after the onset of motor aphasia. Computed tomography (CT) and magnetic resonance imaging (MRI) showed ICH in the left frontal lobe. Angiography revealed DVA in the left frontal lobe in the late venous phase. Stenosis of the collecting vein of DVA at the entrance to the superior sagittal sinus was detected and accompanied by cavernous malformation (CM) beside DVA. Cone-beam CT revealed the absence of the left septal vein and hypoplastic transverse caudate veins. The patient was treated by blood pressure management and no additional neurological symptoms were detected. DVA develops to compensate for the absence of pial or deep venous systems, and generally benign and clinically asymptomatic. However, the outflow restriction of DVA causes chronic venous hypertension and the formation of CM. These abnormalities are considered to occur during post-natal life and may result in ICH. The risk of hemorrhage needs to be considered in cases of DVA with restricted venous outflow or CM.
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  • 文章类型: Journal Article
    麻醉做梦和麻醉意识是截然不同的现象。尽管术中知晓的发生率在手术后报告有梦的患者中更为常见,这两种现象之间的确切关联仍然是一个未解决的问题。这项研究的主要目的是调查麻醉梦,麻醉意识和心理后果最终发生在深度镇静下。术中做梦经历与自然睡眠中的梦特征相关。
    51名患者,在双频谱指数引导的丙泊酚靶控输注深度镇静麻醉下进行纤维腺瘤手术切除,被纳入这项前瞻性研究。通过状态特质焦虑量表进行心理评估。采用问卷记录做梦和麻醉意识。数据收集后出现(t0),24小时(t1),1个月(t2),6个月(t3)。
    6名患者(12%)在t0时报告了麻醉做梦,确认了每次后续评估的反应。一名患者(2%)在麻醉期间确认做梦,但在t0时否认。术中梦内容与自然睡眠中的梦特征之间存在高度相关性。没有发现麻醉意识的病例。在做梦和没有做梦的患者中观察到相似的满意度。
    麻醉做梦似乎并不影响丙泊酚靶控输注深度镇静患者的满意度。心理评估似乎可以改善对做梦患者可能的心理后果的评估。
    UNASSIGNED: Anesthetic dreaming and anesthesia awareness are well distinct phenomena. Although the incidence of intraoperative awareness is more common among patients who reported a dream after surgery, the exact correlation between the two phenomena remains an unsolved rebus. The main purpose of this study was to investigate anesthetic dreaming, anesthesia awareness and psychological consequences eventually occurred under deep sedation. Intraoperative dreaming experiences were correlated with dream features in natural sleep.
    UNASSIGNED: Fifty-one patients, undergoing surgical excision of fibroadenomas under a Bispectral index-guided deep sedation anesthesia with propofol target controlled infusion, were enrolled into this prospective study. Psychological assessment was performed through the State Trait Anxiety Inventory. A questionnaire was adopted to register dreaming and anesthesia awareness. Data were collected after emergence (t0), 24 hours (t1), 1 month (t2), 6 months (t3).
    UNASSIGNED: Six patients (12%) reported anesthetic dreaming at t0 confirming the response at each subsequent evaluation. One patient (2%) confirmed dreaming during anesthesia in all, but denied it at t0. There was a high correlation between the intraoperative dream contents and the features of dreams in natural sleep. No cases of anesthesia awareness were detected. A similar level of satisfaction was observed in dreaming and no-dreaming patients.
    UNASSIGNED: Anesthetic dreaming does not seem to influence satisfaction of patients undergoing deep sedation with propofol target controlled infusion. A psychological assessment would seem to improve the evaluation of possible psychological consequences in dreamer patient.
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  • 文章类型: Case Reports
    Superficial candida infections of the skin are common, but deep cutaneous candidiasis, including secondary dissemination to the skin from systemic candidiasis, candidaemia or primary invasion due to skin defects such as trauma, is rare. These patients are usually immunosuppressed, but immunocompetent hosts can be affected as well. Candida albicans is the most common pathogen. However, non-albicans Candida species can cause deep skin invasion in rare circumstances. We report a case of deep cutaneous candidiasis caused by Candida duobushaemulonii in a 68-year-old man. Deep tissue invasion was confirmed by skin histopathology examination. The pathogen was initially identified as C. haemulonii using the VITEK® 2 system for microbial identification, but was later determined to be C. duobushaemulonii based on sequencing of the internal transcribed spacer region of ribosomal DNA and D1/D2 region of 26S rDNA. The patient was successfully treated with amphotericin B, followed by fluconazole and surgical intervention. To the best of our knowledge, this is the first case of deep cutaneous infection by C. duobushaemulonii.
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    文章类型: Case Reports
    Molybdenum cofactor (MC) deficiency is defined as a progressive neurodegenerative and neurometabolic disease, characterized by convulsions, severe mental and motor retardation resistant to the treatment. Patients with MC deficiency usually need at least sedation for even minor interventions such as dental examination or treatment. Sedation or general anesthesia for these patients may be complicated due to accompanying disorders. However, we were unable to find any reports on anesthetic management of patients with MC deficiency in the literature. In this article, we intend to share our experience of a patient with MC deficiency, who had undergone dental treatment under deep sedation.
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