cumulative live birth rate

累计活产率
  • 文章类型: Journal Article
    IVF周期的目标是每个意向治疗至少一个婴儿的出生。然而,试管婴儿不能赋予胚胎能力,但只能为每对夫妇提供安全的治疗,以满足预定的成功机会。这篇评论强调了临床上,试管婴儿成功的定义应包括财务和以患者为中心的观点.主要结果,这是每次意向治疗的累计活产分娩率,必须始终辅之以风险分析,投入的成本和时间,以及通过测量患者满意度。最后,这是必不可少的,只要临床条件存在,限制尝试失败后停止治疗。对数据的持续监测至关重要,必须根据患者特征进行调整,并与国家和国际登记册进行比较。作者旨在回顾所有这些方面,并强调仍有待讨论的要点。是时候达成共识了吗?
    The goal of an IVF cycle is the birth of at least one baby per intention to treat. However, IVF cannot confer competence on an embryo, but only can provide each couple with a safe treatment to meet a predetermined chance of success. This commentary highlights how clinical, financial and patient-centred perspectives should be included in the definition of success in IVF. The primary outcome, which is the cumulative live birth delivery rate per intention to treat, must always be complemented by analyses of risks, costs and time invested, as well as by measures of patient satisfaction. Finally, it is essential, whenever clinical conditions exist, to limit treatment discontinuation after failed attempts. Constant monitoring of the data is pivotal and must be adjusted for patient characteristics and compared with national and international registers. The authors aimed to review all these aspects and highlight the points that are still open for discussion. Is it time for a consensus?
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  • 文章类型: Journal Article
    Traditionally, IVF success rates have been reported in terms of live birth per fresh cycle or embryo transfer. With the increasing use of embryo freezing and thawing it is essential that we report not only outcomes following fresh but also those after frozen embryo transfer as a complete measure of success of an IVF treatment. Most people agree that an individual\'s chance of having a baby following fresh and frozen embryo transfer should be described as cumulative live birth rate. However, views on the most appropriate parameters required to calculate such an outcome have been inconsistent. There is an additional dimension-time for all frozen embryos to be used up by a couple, which can influence the outcome. Given that cumulative live birth rate is generally perceived to be the preferred reporting system in IVF, it is time to have an international consensus on how this statistic is calculated, reported and interpreted by stakeholders across the world.
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