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克隆
  • 文章类型: Case Reports
    脐带通过向其提供营养和氧气而充当发育中的胎儿的关键生命线。脐带异常被认为是人类死产的主要原因,但是在动物的临床实践中,关于与脐带异常相关的死胎的信息很少。这里,我们描述了一个骆驼胎儿死亡的案例,该案例表明是由于脐带勒死而导致的胎儿死亡,通常被称为颈索。怀孕36周的骆驼自然流产了一个胎儿。骆驼是5岁和无名氏。将6天大的克隆胚胎经宫颈转移至受体。胚胎移植后50天通过超声检查确认妊娠,怀孕的骆驼保持在标准的营养计划下。流产胎儿的脖子被脐带的双环紧紧绞死。胎儿无先天性异常或其他畸形。我们得出的结论是,颈绳紧紧盘绕在胎儿的脖子上,并通过塌陷脐静脉干扰胎儿的血流,随后导致胎儿死亡和流产。就作者所知,这是第一例报告的骆驼颈绳病例。
    The umbilical cord acts as the critical lifeline of the developing fetus by providing nutrients and oxygen to it. Umbilical cord abnormalities are considered the leading cause of stillbirth in humans, but information on stillbirths associated with umbilical cord abnormalities is very scant in the clinical practice of animals. Here, we described a case of fetal demise in camels indicated to be caused by fetal death from strangulation by its umbilical cord, which is commonly known as the nuchal cord. A pregnant camel at its 36 weeks of gestation spontaneously aborted a single fetus. The camel was 5 years old and nullipara. A 6-day-old cloned embryo was transferred transcervically to the recipient. Pregnancy was confirmed 50 days after embryo transfer by ultrasonography, and the pregnant camel was maintained under a standard nutritional plan. The neck of the aborted fetus was strangulated tightly by a double loop of the umbilical cord. There was no congenital anomaly or other malformation in the fetus. We concluded that the nuchal cord was tightly coiled around the neck of the fetus and interfered with the blood flow in the fetus by collapsing the umbilical vein and subsequently causing fetal death and abortion. To the authors\' knowledge, this is the first reported case of a nuchal cord in camels.
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