悲惨的COVID-19大流行影响了全世界许多儿童。在可能影响包括COVID-19在内的病毒感染过程的因素中,目前尚不确定特应性疾病是否具有保护作用或易感作用。该研究旨在通过调查克尔曼特应性儿童中COVID-19的患病率和严重程度来解决知识差距,2022年。克尔曼医科大学对有特应性病史的儿童进行了描述性分析的横断面研究。人口统计信息,特应性(包括过敏性鼻炎,高反应性气道疾病(HRAD)或哮喘,湿疹,荨麻疹,过敏反应,和食物过敏),COVID-19感染史,记录疾病严重程度。共有1007名儿童和青少年,(男生:56.4%,女生:43.6%,年龄:5.61±2.64岁)纳入研究。53.5%的COVID-19感染史呈阳性,75.9%的病例表现出轻度疾病严重程度。过敏的频率是HRAD或哮喘(67.2%),过敏性鼻炎(42.6%),食物过敏(27.4%)。在HRAD或哮喘患者中,COVID-19病例的频率明显较高,而食物过敏患者的比例明显较低,过敏反应,还有湿疹.在特应性个体中,过敏性鼻炎患者的COVID-19严重程度明显较低,而在食物过敏个体中观察到相反的趋势。本研究揭示了儿科患者中特应性和COVID-19的关系。似乎特定类型的异常可能会对COVID-19感染的风险和严重程度产生不同的影响。更好地了解这些关联可以为弱势儿科人群的临床管理和预防措施提供信息。
The tragic COVID-19 pandemic affected many children worldwide. Among the factors that may influence the course of viral infections including COVID-19, it is still uncertain whether atopy has a protective or predisposing role. The
study aims to address the knowledge gap by investigating the prevalence and severity of COVID-19 among atopic children in Kerman, in 2022. A descriptive-analytical cross-sectional
study on children with a history of atopy was performed in Kerman Medical University. Demographic information, type of atopy (including allergic rhinitis, Hyper-Reactive Airway Disease (HRAD) or asthma, eczema, urticaria, anaphylaxis, and food allergy), history of COVID-19 infection, and disease severity were recorded. A total of 1007 children and adolescents, (boys: 56.4%, girls: 43.6%, age:5.61±2.64 years) were included in the
study. History of COVID-19 infection was positive in 53.5%, with 75.9% of the cases exhibiting mild disease severity. The frequency of atopies was HRAD or asthma (67.2%), allergic rhinitis (42.6%), and food allergy (27.4%). The frequency of COVID-19 cases was significantly higher among patients with HRAD or asthma, whereas it was significantly lower among those with food allergies, anaphylaxis, and eczema. Among atopic individuals, COVID-19 severity was significantly lower in those with allergic rhinitis, while the opposite trend was observed among food-allergic individuals. This
study sheds light on the relationship between atopy and COVID-19 among pediatric patients. It seems specific types of atopies may influence the risk and severity of COVID-19 infection differently. A better understanding of these associations can inform clinical management and preventive measures for vulnerable pediatric populations.