扣带,边缘系统的主要结构,包含内侧胆碱能通路,起源于基底前脑的Meynert(Ch4)的基底核。扣带参与各种认知功能,包括记忆,注意,学习,动机,情感,和疼痛感知。在这个小型审查中,回顾了10项关于脑损伤患者受伤的扣带回恢复机制的研究报告。在这10项研究中报道的损伤的前扣带的恢复机制分为以下几类:机制1,通过损伤的扣带和Ch4之间的扣带的正常途径恢复;机制2,通过损伤的扣带和脑干胆碱能核之间的神经束恢复;机制3,通过损伤的扣带和前叶之间的基底神经束之间的神经束恢复,通过前叶的神经束恢复机制4,通过神经束之间的阐明前扣带损伤的恢复机制可能对前扣带损伤患者的神经康复有用。扩散张量纤维束成像似乎可用于检测脑损伤患者前扣带损伤的恢复机制。然而,关于扣带损伤恢复机制的研究仍处于早期阶段,因为上述研究大多是局限于少数脑部病理的病例报告。因此,应鼓励涉及大量患有各种脑部病理的受试者的进一步研究。此外,有必要对与每种恢复机制相关的影响因素和临床结局进行研究.
The
cingulum, a major structure in the limbic system, contains the medial cholinergic pathway, which originates from the basalis nucleus of Meynert (Ch 4) in the basal forebrain. The
cingulum is involved in various cognitive functions, including memory, attention, learning, motivation, emotion, and pain perception. In this mini-
review, 10 studies reporting on recovery mechanisms of injured cinguli in patients with brain injury were reviewed. The recovery mechanisms of the injured anterior cinguli reported in those 10 studies are classified as follows: Mechanism 1, recovery via the normal pathway of the cingulum between the injured cingulum and Ch 4; mechanism 2, recovery through the neural tract between the injured cingulum and the brainstem cholinergic nuclei; mechanism 3, recovery via the lateral cholinergic pathway between the injured
cingulum and the white matter of the temporo-occipital lobes; mechanism 4, recovery through the neural tract between the contralesional basal forebrain and the ipsilesional basal forebrain via the genu of the corpus callosum; and mechanism 5, recovery through the neural tract between the injured cingulum and Ch 4 via an aberrant pathway. Elucidation of the recovery mechanisms of injured anterior cinguli might be useful for neurorehabilitation of patients with anterior cingulum injuries. Diffusion tensor tractography appears to be useful in the detection of recovery mechanisms of injured anterior cinguli in patients with brain injury. However, studies on
cingulum injury recovery mechanisms are still in the early stages because most of the above studies are case reports confined to a few brain pathologies. Therefore, further studies involving large numbers of subjects with various brain pathologies should be encouraged. In addition, studies on the influencing factors and clinical outcomes associated with each recovery mechanism are warranted.