■重型β-地中海贫血是由血红蛋白β链合成受损引起的血液疾病。妊娠期间主要的β-地中海贫血的口腔表现很少报道。
■本研究旨在描述一例患有β-地中海贫血的孕妇的口腔表现,以进行多学科管理。
■一个27岁的女人,患有重型β地中海贫血,每月接受常规输血形式的治疗并服用抗螯合药物,但由于怀孕,目前正在停止这种治疗,目前怀孕16周,抱怨牙龈肿胀,出血,还有口臭.口外检查显示干燥,去角质的嘴唇。口内检查发现牙龈增生伴红斑,软一致性,深红色圆形牙龈边缘,出血,真正的口袋和整个阴唇的疼痛,颊,腭,和语言。该患者无全身性疾病史。病人从未去过牙医,无论是以前还是现在,抱怨她的口腔。血液学参数显示异常,外周血检查显示感染。口腔诊断包括牙龈肿大和与妊娠和重型β-地中海贫血相关的慢性牙周炎。
■牙科管理包括用3%过氧化氢(H2O2)缠绕,二氧化氯喷口水,抗生素,微积分去除,和口腔卫生说明。每月输血一次,妊娠期间停止抗螯合治疗。经过三个月的多学科管理,结果令人满意。
■多学科,对患有重型β-地中海贫血的孕妇进行口腔表现的非手术治疗与牙科和医学协作治疗显示出令人满意的结果。
UNASSIGNED: Beta-thalassemia major is a blood disorder caused by impaired synthesis of hemoglobin beta chain. Oral manifestations of beta-thalassemia major in pregnancy have rarely been reported.
UNASSIGNED: This study aimed to describe a
case of oral manifestations in a pregnant woman with beta-thalassemia major for multidisciplinary management.
UNASSIGNED: A 27-year-old woman, suffering from beta thalassemia major who is undergoing therapy in the form of routine blood transfusions every month and taking anti-chelation drugs but is currently stopping this because she is pregnant, currently 16 weeks pregnant, complains complained of swollen gums, bleeding, and bad breath. Extraoral examination revealed dry, exfoliative lips. Intraoral examination revealed gingival hyperplasia with erythema, soft consistency, dark red rounded gingival margins, bleeding, true pockets and pain throughout the labial, buccal, palatal, and lingual. There was no history of systemic disease in this patient. Patient has never visited a dentist, either before or now, with complaints about her oral cavity. Hematological parameters showed abnormalities, and peripheral blood examination revealed an infection. The oral diagnoses included gingival enlargement and chronic periodontitis associated with pregnancy and β- thalassemia major.
UNASSIGNED: Dental management consisted of spooling with 3% hydrogen peroxide (H2O2) spooling, chlorine dioxide spray mouthwash, antibiotics, calculus removal, and oral hygiene instructions. Blood transfusions were administered once a month, and anti-chelation therapy was stopped during pregnancy. After three months of multidisciplinary management, the results were satisfactory.
UNASSIGNED: Multidisciplinary, collaborative dental and medical management with non-surgical therapy of oral manifestations in pregnant women with beta-thalassemia major showed satisfactory results.