■在过去的二十年里,鼻内镜颅底手术(EESBS)通过使切除脑膜瘤等重要病理的机会最少,彻底改变了颅底肿瘤的治疗。垂体腺瘤,和脊索瘤.尽管它的功效,并发症,如脑脊液(CSF)泄漏构成重大挑战,EESBS后的平均发病率为8.9%。因此,我们的研究目的是调查在采用内镜经鼻入路颅底手术后与术后脑脊液漏相关的危险因素,专注于在吉达的阿卜杜勒-阿齐兹国王医疗城和麦加的阿卜杜拉国王医疗城接受治疗的患者,沙特阿拉伯。
■对2016年1月至2022年12月期间接受内镜经鼻入路切除硬膜内颅底病变的患者进行回顾性回顾,共51例患者。收集了基本的人口统计数据,伴随着患者的合并症,出现症状,肿瘤病理学,肿瘤部位,切除的程度,和结果。
■对51名参与者进行了分析,平均年龄43.41岁.男性参与者(58.8%),头痛是最常见的症状(74.5%),其次是视觉障碍(51.0%)。非分泌性肿瘤占优势,主要位于鞍区和鞍上区域(58.8%)。大体全切除术占大多数(56.9%),术后脑脊液漏发生率为9.8%。值得注意的是,所有4例脑脊液漏患者都经历了术前头痛.高血压在病例1和4中普遍存在,病例4有神经系统疾病和放射治疗史。前颅底肿瘤在病例3和4中最常见。
■本研究中手术后脑脊液漏的发生率与先前报道的相似。值得注意的是,重复手术可能会增加术后脑脊液漏的风险。因此,仔细评估肿瘤切除和颅底重建的手术方法很重要,考虑到肿瘤的特点和患者的整体状况。
UNASSIGNED: Over the past two decades, endoscopic endonasal skull base surgery (EESBS) has revolutionized the treatment of skull base tumors by enabling minimal access to resect significant pathologies such as meningiomas, pituitary adenomas, and chordomas. Despite its efficacy, complications such as cerebrospinal fluid (CSF) leak pose significant challenges, with an average incidence of 8.9% following EESBS. Therefore, our study aims to investigate the risk factors associated with postoperative CSF leak after employing an endoscopic endonasal approach for skull base surgery, focusing on patients treated at King Abdul-Aziz Medical City in Jeddah and King Abdullah Medical City in Makkah, Saudi Arabia.
UNASSIGNED: A retrospective review of patients who underwent an endoscopic endonasal approach for the resection of intradural skull base pathology between January 2016 and December 2022 was performed with a total of 51 patients. Basic demographic data were collected, along with patient comorbidities, presenting symptoms, tumor pathology, tumor site, the extent of resection, and outcomes.
UNASSIGNED: 51 participants were analyzed, with a mean age of 43.41. Male participants comprised (58.8%), while headaches were the most common symptom (74.5%), followed by visual disturbances (51.0%). Nonsecretory tumors predominated, primarily located in the sellar and suprasellar regions (58.8%). Gross total resection was performed in the majority (56.9%), with a 9.8% incidence of postoperative CSF leak. Notably, all four patients with CSF leak experienced preoperative headaches. Hypertension was prevalent in Cases 1 and 4, with Case 4 having a history of neurological disease and radiation therapy. Anterior skull base tumors were most frequent in Cases 3 and 4.
UNASSIGNED: The incidence of CSF leakage after surgery in this study was similar to that previously reported. It is worth noting that repeated surgeries may increase the risk of postoperative CSF leakage. Therefore, it is important to carefully evaluate the surgical approach for tumor removal and skull base reconstruction, considering the tumor characteristics and the patient\'s overall condition.