背景：本研究调查了跟骨单纯性骨囊肿（跟骨囊肿）和长骨囊肿（长骨囊肿）之间潜在的临床病理差异。
方法：对接受手术治疗的41例患者的41个囊肿进行了评估：跟骨16个囊肿，17在肱骨，7在股骨中，1在胫骨。临床过程，放射学发现，和组织学特征进行了回顾性分析。
结果：患者平均年龄为11.5岁（范围，3至25年），平均随访33.0个月(范围，12至77个月）。跟骨囊肿患者的平均年龄明显较高（13.5岁；长骨囊肿，10.2年,P<0.05)。跟骨囊肿患者未见治疗失败，7个长骨囊肿需要再次手术。在H&E染色的囊壁标本中,16例跟骨囊肿中有10例（62.5%）出现胆固醇裂，而在长骨囊肿中均未发现（0％；P<0.0001）。
结论：我们的研究阐明了跟骨囊肿和长骨囊肿之间存在的不同临床病理特征。胆固醇裂开最可能是由于出血和随后的囊肿中的血液分解。长骨囊肿和跟骨囊肿之间这些差异的意义仍有待推测。
方法：三级，回顾性比较系列。
BACKGROUND: The potential unrevealed clinicopathological differences between simple bone cysts situated in the calcaneus (calcaneal bone cysts) and those situated in long bones (long bone cysts) were investigated in the present
study.
METHODS: A total of 41 cysts from 41 patients who underwent operative treatment were evaluated: 16 cysts in the calcaneus, 17 in the humerus, 7 in the femur, and 1 in the tibia. The clinical course, radiological findings, and histological features were retrospectively reviewed.
RESULTS: The mean patient age was 11.5 years (range, 3 to 25 years), and the mean follow-up was 33.0 months (range, 12 to 77 months). The mean patient age was significantly higher in patients with calcaneal bone cysts (13.5 years; long bone cysts, 10.2 years, P < .05). No treatment failure was seen for patients with calcaneal bone cysts, while 7 long bone cysts required reoperation. In H&E-stained specimens of the cyst wall, cholesterol clefts were identified in 10 of the 16 calcaneal bone cysts (62.5%), whereas none were identified in long bone cysts (0%; P < .0001).
CONCLUSIONS: Our
study elucidates the different clinicopathological features existing between calcaneal bone cysts and long bone cysts. Cholesterol clefting is most likely due to hemorrhaging and the subsequent breakdown of blood in the cyst. The significance of these differences between long bone and calcaneal cysts is still open to conjecture.
METHODS: Level III, retrospective comparative series.
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