UNASSIGNED:额叶脑功能障碍是神经康复的主要挑战。神经反馈(NF),作为一种基于脑电图的大脑训练方法,目前应用于广泛的精神健康状况,包括创伤性脑损伤.
UNASSIGNED:本研究旨在探索低频神经反馈(ILF-NF)促进额叶脑损伤患者脑功能恢复的能力。
UNASSIGNED:在瑞士的神经康复诊所住院的20名患者,额叶和可选的其他脑部病变被随机分配接受NF或sham-NF.使用关于内在警觉性的正面评估电池(FAB)和注意力表现测试(TAP)任务评估认知改善。阶段性警觉和冲动控制。
未经评估:关于认知改善,在20次NF或sham-NF治疗后,两组之间没有显着差异。然而,在主要为额叶脑部病变的患者亚组中,NF-组通过FAB和内在警觉性测量的改善明显更高。
UNASSIGNED:这是第一个使用NF在脑损伤恢复中的双盲对照研究,因此也是对ILFNF的首次此类研究。尽管由于参与者人数少,小组的结果意义有限,它强调了整个组中关于FAB和内在警觉性的趋势(分别为p=0.068,p=0.079)。因此,我们得出结论,NF可能是促进额叶脑部病变恢复的有希望的候选者。需要更多的患者和更少的病变异质性的进一步研究来验证NF在额叶脑损伤患者的神经康复中的有用性(NCT02957695ClinicalTrials.gov)。
UNASSIGNED: Frontal brain dysfunction is a major challenge in neurorehabilitation. Neurofeedback (NF), as an EEG-based brain training method, is currently applied in a wide spectrum of mental health conditions, including traumatic brain injury.
UNASSIGNED: This
study aimed to explore the capacity of Infra-Low Frequency Neurofeedback (ILF-NF) to promote the recovery of brain function in patients with frontal brain injury.
UNASSIGNED: Twenty patients hospitalized at a neurorehabilitation clinic in Switzerland with recently acquired, frontal and optionally other brain lesions were randomized to either receive NF or sham-NF. Cognitive improvement was assessed using the Frontal Assessment Battery (FAB) and the Test of Attentional Performance (TAP) tasks regarding intrinsic alertness, phasic alertness and impulse control.
UNASSIGNED: With respect to cognitive improvements, there was no significant difference between the two groups after 20 sessions of either NF or sham-NF. However, in a subgroup of patients with predominantly frontal brain lesions, the improvements measured by the FAB and intrinsic alertness were significantly higher in the NF-group.
UNASSIGNED: This is the first double-blind controlled
study using NF in recovery from brain injury, and thus also the first such
study of ILF NF. Although the result of the subgroup has limited significance because of the small number of participants, it accentuates the trend seen in the whole group regarding the FAB and intrinsic alertness (p = 0.068, p = 0.079, respectively). We therefore conclude that NF could be a promising candidate promoting the recoveryfrom frontal brain lesions. Further studies with larger numbers of patients and less lesion heterogeneity are needed to verify the usefulness of NF in the neurorehabilitation of patients with frontal brain injury (NCT02957695 ClinicalTrials.gov).