我们报告了加巴喷丁和可乐定治疗酒精戒断综合征期间发生后部可逆性脑病综合征(PRES)的病例。病人出现了严重的高血压,混乱和震颤,最终导致双侧视力丧失和癫痫发作。影像学提示后脑水肿。使用苯二氮卓类药物治疗,抗高血压药,和抗癫痫药物导致解决。一年后,成像显示了发现的分辨率。我们回顾了相关文献,并提出了对PRES子实体的识别,酒精相关的PRES(ARPRES),这可能出现在酒精戒断综合征的背景下,长期饮酒,急性酒精中毒,有或没有高血压。
We report a
case of posterior reversible encephalopathy syndrome (PRES) during treatment for alcohol withdrawal syndrome with gabapentin and clonidine. The patient developed severe hypertension, confusion and tremor, culminating in bilateral vision loss and a seizure. Imaging revealed posterior cerebral edema. Treatment with benzodiazepines, antihypertensives, and anti-seizure medications led to resolution. One year later, imaging showed resolution of the findings. We review the associated literature and propose the recognition of a PRES sub-entity, Alcohol-Related PRES (ARPRES), which can appear in the setting of alcohol withdrawal syndrome, chronic alcohol use, and acute alcohol intoxication, with or without hypertension.