背景:心理健康是影响儿童整体幸福感的重要因素。国家健康统计数据显示,每年有数百万儿童被诊断患有精神健康障碍,来自铅和双酚等化学污染物研究的证据表明,环境暴露与年轻人的心理健康疾病有关。然而,儿童心理健康与环境之间的关系还没有得到很好的理解。本文旨在回顾有关产前和/或儿童环境化学暴露以及与情绪有关的心理健康问题的最新文献。焦虑,和行为。这项工作还确定了数据不足的领域,并提出了填补数据空白的建议。方法:通过搜索GoogleScholar和PubMed在过去6年(2017-2022年)发表的文献进行叙事回顾,使用与儿童相关的搜索词,心理健康,和环境化学暴露。通过筛选这些论文中的参考文献确定了其他相关研究。结果:本综述共包括29项研究,结果按化学类别进行了总结:重金属,内分泌干扰物,和杀虫剂。大多数研究报告了化学暴露与儿童心理健康结果之间的积极和显着关联,包括内在化和外在化行为。结论:这篇综述表明,越来越多的文献表明,发育中暴露于某些环境化学物质会增加儿童的情绪风险,焦虑,和行为问题。未来的研究应该扩大这些发现,以了解累积影响,化学混合物,神经毒性机制,性别差异,和脆弱之窗。
Background: Mental health is an important factor for children\'s overall wellbeing. National health statistics show that millions of children are diagnosed with mental health disorders every year, and evidence from studies on chemical pollutants like lead and bisphenols indicate that environmental exposures are linked to mental health illnesses in youth. However, the relationship between children\'s mental health and the environment is not well understood. This paper aims to
review recent literature on prenatal and/or childhood environmental chemical exposures and mental health problems related to mood, anxiety, and behavior. This work also identifies areas of insufficient data and proposes suggestions to fill the data gaps. Methods: A narrative
review was performed by searching Google Scholar and PubMed for literature published in the last 6 years (2017-2022), using search terms related to children, mental health, and environmental chemical exposure. Additional relevant studies were identified by screening the references in these papers. Results: A total of 29 studies are included in this
review and results are summarized by chemical category: heavy metals, endocrine-disrupting chemicals, and pesticides. The majority of studies reported positive and significant associations between chemical exposures and child mental health outcomes including internalizing and externalizing behaviors. Conclusion: This
review demonstrates that there is a growing body of literature that suggests developmental exposure to some environmental chemicals increases a child\'s risk of mood, anxiety, and behavior problems. Future research should expand on these findings to understand cumulative impacts, chemical mixtures, neurotoxic mechanisms, sex differences, and windows of vulnerability.