背景:脑动脉瘤和左心房粘液瘤之间的关联是已知的,但很少见。我们描述了它的发病机制,临床表现,使用文献系统综述的诊断结果和治疗。方法:通过PubMed搜索MEDLINE,使用关键字“心房粘液瘤”搜索直到2022年8月发表的文章,“心脏粘液瘤”和“脑动脉瘤”。结果:在这篇综述中,55例多发性粘液瘤动脉瘤患者进行了分析,65%是女性。诊断动脉瘤的平均年龄为42.5±15.81;大多数患者年龄小于60岁(86%)。动脉瘤可以在诊断前发现,与心脏粘液瘤同时发生,甚至在切除心房肿块后25年。在我们的审查中,平均诊断时间为4.5年.我们的综述估计,最常见的症状是血管事件(25%)和癫痫发作(14.3%)。在15个案例中,报告了可变的头痛。关于管理策略,57%的病例以保守治疗为主要选择。结论:尽管由心房粘液瘤引起的脑动脉瘤很少见,长期后果可能很严重,应该对患者进行监测。
Background: The association between cerebral aneurysms and left atrial myxoma is known but rare. We described its pathogenesis, clinical presentation, diagnostic findings and treatment using a systemic
review of the literature. Methods: MEDLINE via PubMed was searched for articles published until August 2022 using the keywords \"atrial myxoma\", \"cardiac myxoma\" and \"cerebral aneurysm\". Results: In this
review, 55 patients with multiple myxomas aneurysms were analyzed, and 65% were women. The average age when aneurysms were diagnosed was 42.5 ± 15.81; most patients were less than 60 years old (86%). Aneurysms could be found before the diagnosis, at the same time as cardiac myxoma, or even 25 years after resection of the atrial mass. In our
review, the mean time to diagnoses was 4.5 years. Our
review estimates that the most common symptoms were vascular incidents (25%) and seizures (14.3%). In 15 cases, variable headaches were reported. Regarding management strategies, 57% cases were managed conservatively as the primary choice. Conclusions: Although cerebral aneurysms caused by atrial myxoma are rare, the long-term consequences can be serious and patients should be monitored.