随着辅助生殖技术的快速发展,各种生殖障碍已得到有效解决。针灸疗法,包括电针(EA)和经皮穴位电刺激(TEAS),在世界范围内变得更加流行。越来越多的证据表明,EA和TEAS可有效治疗妇科疾病,尤其是不孕症。本文介绍了如何从中医理论的角度选择治疗不孕症的穴位,以及如何根据动物和临床研究结果确定EA/TEAS电脉冲的关键参数。总结了EA/TEAS治疗各种生殖障碍的临床应用原则,如多囊卵巢综合征(PCOS),取卵引起的疼痛,卵巢储备减少,胚胎移植,和少精子症/弱精子症。还研究了介导EA/TEAS在生殖医学中的治疗作用的可能潜在机制。
With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture (EA) and transcutaneous electrical acupoint stimulation (TEAS), become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of EA/TEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/TEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome (PCOS), pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligospermia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.