湖水红球菌(Girod-Chantrans)Rostafinski(Chlorophyta)是虾青素最丰富的微藻来源。来自H.lacustris的天然虾青素已被广泛研究并用于世界范围内的商业生产。在这项研究中,我们检查了11种抗生素(硫酸双氢链霉素,新霉素,氯霉素,青霉素,链霉素,氨苄青霉素,卡那霉素,庆大霉素,潮霉素B,四环素,和巴龙霉素)对生物质干重的影响,增长,使用Jaworski\的无氮源培养基,以及H.lacustris的虾青素产量。在氨苄青霉素的存在下,H.lacustris中的虾青素含量得到了提高(0.25g/L,0.5g/L,1g/L),氯霉素(0.25g/L),和青霉素(0.25g/L,0.5g/L,1g/L)与第15天的对照相比。与对照相比,添加青霉素(0.5g/L)在第15天获得虾青素含量的最大增加(6.69倍)。同样,在第15天,对于添加青霉素(0.5g/L)生长的H.lacustris培养物,细胞数量也是最高的。
Haematococcus lacustris (Girod-Chantrans) Rostafinski (Chlorophyta) is the richest microalgal source of
astaxanthin. Natural
astaxanthin from H. lacustris has been widely studied and used for commercial production worldwide. In this study, we examined the effects of 11 antibiotics (dihydrostreptomycin sulphate, neomycin, chloramphenicol, penicillin, streptomycin, ampicillin, kanamycin, gentamycin, hygromycin B, tetracycline, and paromomycin) on the biomass dry weight, growth, and
astaxanthin yield of H. lacustris using Jaworski\'s medium without a nitrogen source.
Astaxanthin content in H. lacustris was improved in the presence of ampicillin (0.25 g/L, 0.5 g/L, 1 g/L), chloramphenicol (0.25 g/L), and penicillin (0.25 g/L, 0.5 g/L, 1 g/L) in comparison to the control on day 15. The greatest increase in
astaxanthin content on day 15 (6.69-fold) was obtained with the addition of penicillin (0.5 g/L) in comparison to the control. Similarly, on day 15, the cell numbers were also the highest for the H. lacustris culture grown with the addition of penicillin (0.5 g/L).