assisted ventilation

辅助通气
  • 文章类型: Journal Article
    背景:COVID-19已成为全球范围内急性呼吸窘迫综合征(ARDS)的最常见原因。病理生理学和临床表现的特征部分区别于经典ARDS。一项研究与开发(RAND)分析衡量了一个专家小组关于使用和不使用COVID-19作为诱发原因的ARDS管理的意见,使用最近的英国指南作为模板。
    方法:由重症监护医生组成的11人小组评估了入院期间不同时间ARDS管理方案的适当性,在存在或不存在的情况下,或SARS-CoV-2感染的严重程度在1-9级(其中1-3是不合适的,4-6是不确定的,7-9是合适的)。在RAND方法专家主持的在线会议上讨论了匿名结果的摘要。修改后的在线调查包括76个问题,细分为调查(16),无创呼吸支持(18),ARDS的基础重症监护病房管理(20),难治性低氧血症的管理(8),药物治疗(7)和抗凝治疗(7),再次完成。
    结果:专家之间的分歧仅在解决确诊或疑似COVID-19患者的诊断支气管镜检查的适当性时才是显著的。建议遵循现有已发布的相关循证干预措施的ARDS管理指南。专家对最终调查的回应建议ARDS的支持性管理应该是相同的,无论COVID-19诊断如何。对于患有COVID-19的ARDS患者,专家组建议使用皮质类固醇进行常规治疗,并基于对静脉血栓栓塞性疾病的高度怀疑指数,建议降低完全抗凝的阈值。
    结论:专家小组发现没有理由偏离最近指南中概述的基于证据的支持ARDS管理策略。
    BACKGROUND: COVID-19 has become the most common cause of acute respiratory distress syndrome (ARDS) worldwide. Features of the pathophysiology and clinical presentation partially distinguish it from \'classical\' ARDS. A Research and Development (RAND) analysis gauged the opinion of an expert panel about the management of ARDS with and without COVID-19 as the precipitating cause, using recent UK guidelines as a template.
    METHODS: An 11-person panel comprising intensive care practitioners rated the appropriateness of ARDS management options at different times during hospital admission, in the presence or absence of, or varying severity of SARS-CoV-2 infection on a scale of 1-9 (where 1-3 is inappropriate, 4-6 is uncertain and 7-9 is appropriate). A summary of the anonymised results was discussed at an online meeting moderated by an expert in RAND methodology. The modified online survey comprising 76 questions, subdivided into investigations (16), non-invasive respiratory support (18), basic intensive care unit management of ARDS (20), management of refractory hypoxaemia (8), pharmacotherapy (7) and anticoagulation (7), was completed again.
    RESULTS: Disagreement between experts was significant only when addressing the appropriateness of diagnostic bronchoscopy in patients with confirmed or suspected COVID-19. Adherence to existing published guidelines for the management of ARDS for relevant evidence-based interventions was recommended. Responses of the experts to the final survey suggested that the supportive management of ARDS should be the same, regardless of a COVID-19 diagnosis. For patients with ARDS with COVID-19, the panel recommended routine treatment with corticosteroids and a lower threshold for full anticoagulation based on a high index of suspicion for venous thromboembolic disease.
    CONCLUSIONS: The expert panel found no reason to deviate from the evidence-based supportive strategies for managing ARDS outlined in recent guidelines.
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  • 文章类型: Editorial
    暂无摘要。
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  • 文章类型: Consensus Development Conference
    电阻抗层析成像(EIT)经历了30年的发展。使用该技术的功能性胸部检查被认为是临床相关的,特别是监测机械通气患者的局部肺通气和慢性肺疾病患者的局部肺功能检测。随着EIT成为一种成熟的医疗技术,它需要共识审查,命名法,数据分析和解释方案。这种共识是需要比较的,了解和复制来自不同研究小组的研究结果,为了进行大型临床试验,最终,常规临床使用。需要建议如何应用EIT发现来生成诊断并影响临床决策和治疗计划。这份协商一致文件是由一个国际工作组编写的,合作开展EIT的临床推广,称为翻译性EIT发展研究小组。它通过提供(1)对胸部EIT检查和数据分析中涉及的核心过程进行新分类来解决所述需求,(2)专注于具有结构化审查和展望的临床应用(分别适用于成人和新生儿/儿科患者),(3)一个结构化的框架来分类和理解分析方法及其临床作用之间的关系,(4)共识,统一的术语与临床用户友好的定义和解释,(5)回顾胸部EIT的所有主要工作,以及(6)对未来发展的建议(193页与主要文件的主要部分系统地链接的在线补充)。我们希望这些信息对使用EIT的临床医生和研究人员有用,以及该技术的行业生产商。
    Electrical impedance tomography (EIT) has undergone 30 years of development. Functional chest examinations with this technology are considered clinically relevant, especially for monitoring regional lung ventilation in mechanically ventilated patients and for regional pulmonary function testing in patients with chronic lung diseases. As EIT becomes an established medical technology, it requires consensus examination, nomenclature, data analysis and interpretation schemes. Such consensus is needed to compare, understand and reproduce study findings from and among different research groups, to enable large clinical trials and, ultimately, routine clinical use. Recommendations of how EIT findings can be applied to generate diagnoses and impact clinical decision-making and therapy planning are required. This consensus paper was prepared by an international working group, collaborating on the clinical promotion of EIT called TRanslational EIT developmeNt stuDy group. It addresses the stated needs by providing (1) a new classification of core processes involved in chest EIT examinations and data analysis, (2) focus on clinical applications with structured reviews and outlooks (separately for adult and neonatal/paediatric patients), (3) a structured framework to categorise and understand the relationships among analysis approaches and their clinical roles, (4) consensus, unified terminology with clinical user-friendly definitions and explanations, (5) a review of all major work in thoracic EIT and (6) recommendations for future development (193 pages of online supplements systematically linked with the chief sections of the main document). We expect this information to be useful for clinicians and researchers working with EIT, as well as for industry producers of this technology.
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  • 文章类型: Journal Article
    A task force issued from the Groupe Assistance Ventilatoire (GAV) of the Société de Pneumologie de Langue Française (SPLF) was committed to develop a series of expert advice concerning various practical topics related to long-term non invasive ventilation by applying the Choosing Wisely® methodology. Three topics were selected: monitoring of noninvasive ventilation, the interpretation of data obtained from built-in devices coupled to home ventilators and the role of hybrid modes (target volume with variable pressure support. For each topic, the experts have developed practical tips based on a comprehensive analysis of recent insights and evidence from the literature and from clinical experience.
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