自身免疫性多腺综合征II(APS-II),也被称为施密特综合征,是一种罕见的内分泌疾病,以内分泌和非内分泌疾病为特征。艾迪生的疾病和至少一个额外的自身免疫性疾病,如自身免疫性甲状腺疾病或1型糖尿病(T1DM),是APS-II的特征。它可能是由遗传和非遗传因素引起的。我们介绍了一例60岁的女性患者,有T1DM病史,最近诊断为桥本甲状腺炎,因低钠血症进入肾脏科。调查显示存在肾上腺功能不全(AI),所以她被诊断出患有APS-II,并且患有这种综合症的全部三联症。因此,重要的是要考虑已经患有一种或多种自身免疫性疾病的患者的AI或其他自身免疫性疾病的诊断。
Autoimmune polyglandular syndrome II (APS-II), also known as Schmidt syndrome, is a rare endocrine disorder characterized by endocrine and non-endocrine illnesses. Addison\'s disease and at least one additional autoimmune condition, such as autoimmune thyroid disease or type 1 diabetes mellitus (T1DM), are features of APS-II. It can result from genetic and non-genetic factors. We present a
case of a 60-year-old female patient with a history of T1DM and a recent diagnosis of Hashimoto\'s thyroiditis who was admitted to the nephrology department for hyponatremia. Investigations showed the presence of adrenal insufficiency (AI), so she was diagnosed with APS-II and had the full triad of this syndrome. Thus, it is important to think about the diagnosis of AI or other autoimmune conditions in a patient who already has one or more autoimmune diseases.