acute type A aortic dissection

急性 A型主动脉夹层
  • 文章类型: Case Reports
    主动脉夹层(AD)是一种罕见但通常致命的疾病,如果没有适当和紧急治疗。大多数情况下,患者到达急性血流动力学不稳定和撕裂胸痛。病人的生命在很大程度上取决于尽快做出正确的诊断。我们描述了一名60岁的男子,他来到急诊室,出现脑中风的症状,包括意识差,左边的弱点,和与血流动力学不稳定相关的言语障碍,和胸痛。CT血管造影(CTA)观察胸主动脉弓夹层。此外,CTA显示夹层向近端延伸到左颈总动脉,左锁骨下动脉,头臂躯干,右侧颈总动脉和左侧髂总动脉远端,再加上左髂总动脉明显狭窄.正确管理血压(BP)参数可以挽救患者的生命。由于我们医院不提供心胸外科服务,病人被转移到另一个机构,在那里,他立即接受了专家团队的医疗护理,并接受了手术。
    Aortic dissection (AD) is a rare but often lethal condition if not properly and urgently treated. Most often, patients arrive with acute hemodynamic instability and ripping chest agony. The patient\'s life depends critically on a correct diagnosis made as soon as possible. We describe a 60-year-old man who arrived at the emergency room with symptoms of a brain stroke, including poor consciousness, left-sided weakness, and speech disturbance associated with hemodynamic instability, and chest pain. Thoracic aortic arch dissection was observed on CT angiography (CTA). In addition, CTA revealed that the dissection extends proximally into the left common carotid artery, left subclavian artery, brachiocephalic trunk, and right common carotid artery and distally to the left common iliac artery, coupled with significant stenosis of the left common iliac artery. Proper management of blood pressure (BP) parameters is life-saving for the patient. Since our hospital did not offer cardiothoracic surgery services, the patient was transferred to a different institution, where he received medical care immediately from an expert team and had surgery.
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  • 文章类型: Journal Article
    一名53岁男子在开车时突然出现胸部和背部疼痛,导致事故。计算机断层扫描显示急性A型主动脉夹层伴左下肢灌注不良,腹膜后外渗,前纵隔血肿,和直肠膀胱袋中的腹水。主动脉修补术前剖腹探查显示肠穿孔和腹膜后出血,修复过的,并进行了升主动脉置换术.有活动性出血的内脏外伤应优先治疗,即使在主动脉夹层手术期间急性A型主动脉夹层伴随着全身肝素化的需要。
    A 53-year-old man suddenly developed chest and back pain while driving, resulting in an accident. Computed tomography revealed acute type A aortic dissection with malperfusion of the left lower extremity, retroperitoneal extravasation, hematoma in the anterior mediastinum, and ascites in the rectovesical pouch. Exploratory laparotomy before aortic repair revealed intestinal perforation and retroperitoneal bleeding, which were repaired, and an ascending aortic replacement was performed. Visceral trauma with active bleeding should be treated with priority, even if the need for systemic heparinization accompanies acute type A aortic dissection during surgery for aortic dissection.
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  • 文章类型: Journal Article
    目的:本研究提出了一种新的体积-结果(V-O)荟萃分析方法,以确定需要集中的心血管干预措施的最佳年度住院病例量阈值。这种新方法应用于急性A型主动脉夹层(ATAAD)的手术作为说明性示例。
    方法:对三个电子数据库进行了系统搜索(2012年1月1日至2023年3月29日)。主要结果是早期死亡率与年住院病例量的关系。数据按体积四分位数(Qs)表示。使用受限三次样条来证明V-O关系,并应用弯管法确定最佳箱容。对于临床解释,计算需要治疗的数量(NNT)。
    结果:纳入140项研究,包括38276名患者。观察到显著的非线性V-O效应(p<0.001),早期死亡率的四分位数之间存在显着差异(10.3%[Q4]与16.2%[第一季度],p<0.001)。确定的最佳年病例量为38例/年(95%CI37-40例/年,NNT以最佳音量保存在中心的生命与10例/年=21)。对于长期生存率,观察到更明显的四分位数之间的生存差异(10年生存率[Q4]69%vs.[Q1]51%,p<0.001,调整后的HR0.83,95%CI0.75-0.91每四分位数,NNT以高容量拯救生命[Q4]与低容量中心[Q1)=6)。
    结论:使用这种新颖的方法,在统计学上确定了最佳的医院病例量阈值.将ATAAD护理集中到高容量中心可能会改善结果。该方法可以应用于需要集中的各种其他心血管手术。
    The current study proposes a novel volume-outcome (V-O) meta-analytical approach to determine the optimal annual hospital case volume threshold for cardiovascular interventions in need of centralization. This novel method is applied to surgery for acute type A aortic dissection (ATAAD) as an illustrative example.
    A systematic search was applied to three electronic databases (1 January 2012 to 29 March 2023). The primary outcome was early mortality in relation to annual hospital case volume. Data were presented by volume quartiles (Qs). Restricted cubic splines were used to demonstrate the V-O relation, and the elbow method was applied to determine the optimal case volume. For clinical interpretation, numbers needed to treat (NNTs) were calculated.
    One hundred and forty studies were included, comprising 38 276 patients. A significant non-linear V-O effect was observed (P < .001), with a notable between-quartile difference in early mortality rate [10.3% (Q4) vs. 16.2% (Q1)]. The optimal annual case volume was determined at 38 cases/year [95% confidence interval (CI) 37-40 cases/year, NNT to save a life in a centre with the optimal volume vs. 10 cases/year = 21]. More pronounced between-quartile survival differences were observed for long-term survival [10-year survival (Q4) 69% vs. (Q1) 51%, P < .01, adjusted hazard ratio 0.83, 95% CI 0.75-0.91 per quartile, NNT to save a life in a high-volume (Q4) vs. low-volume centre (Q1) = 6].
    Using this novel approach, the optimal hospital case volume threshold was statistically determined. Centralization of ATAAD care to high-volume centres may lead to improved outcomes. This method can be applied to various other cardiovascular procedures requiring centralization.
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  • 文章类型: Case Reports
    主动脉夹层(AD)是一种危及生命的疾病,表现出多样化和非典型的症状,这使得诊断具有挑战性。我们介绍了一个40多岁的妇女,她因崩溃而向急诊科就诊,右侧的弱点,激动,和困惑。尽管努力,在做出明确诊断之前,她心脏骤停并死亡。尸检显示,由于升主动脉的解剖而引起的心包积血是死亡的原因。这个案例突出了诊断AD的困难和需要高怀疑指数,尤其是出现神经系统症状和危险因素的患者。
    Aortic dissection (AD) is a life-threatening condition that presents with diverse and atypical symptoms, making it challenging to diagnose. We present a case of a woman in her 40s who presented to the emergency department with collapse, right-sided weakness, agitation, and confusion. Despite efforts, she went into cardiac arrest and died before a definitive diagnosis was made. The post-mortem examination revealed hemopericardium due to dissection of the ascending thoracic aorta as the cause of death. This case highlights the difficulty in diagnosing AD and the need for a high index of suspicion, especially in patients presenting with neurological symptoms and risk factors.
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  • 文章类型: Case Reports
    急性A型主动脉夹层(ATAAD)是一种危及生命的血管疾病。我们报告了使用3D打印辅助的预加窗涂层支架结合原位开窗技术进行介入治疗的ATAAD病例。几乎没有并发症,患者恢复顺利。
    Acute type A aortic dissection (ATAAD) is a life-threatening vascular disease. We report a case of ATAAD treated with interventional therapy using 3D-printing assisted pre-windowing coated stent combined with in situ window-opening technology. There were few complications and the patient experienced an uneventful recovery.
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  • 文章类型: Journal Article
    BACKGROUND: Acute type A aortic dissections have an extremely poor prognosis, and cardiac tamponade is a major cause of death in these patients. Here, we describe a case where congenital partial pericardial defect relieved cardiac tamponade caused by ruptured type A aortic dissection.
    METHODS: A 79-year-old woman was hospitalized after experiencing chest pains and respiratory distress. She developed out-of-hospital cardiopulmonary arrest and was resuscitated with no sequelae 5 days before admission. Computed tomography confirmed pericardial and left pleural effusions, and type A aortic dissection was diagnosed. We began emergency ascending aortic replacement surgery under general anesthesia with propofol and remifentanil and incidentally discovered a congenital partial left-sided pericardial defect that allowed drainage of the hemopericardium and relieved cardiac tamponade. The surgery was successfully performed, and the patient recovered without complications.
    CONCLUSIONS: We experienced an extremely rare case where a congenital partial pericardial defect relieved cardiac tamponade associated with aortic dissection and contributed to the patient\'s survival.
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  • 文章类型: Journal Article
    BACKGROUND: Achondroplasia is an inherited disorder and the most common type of short-limbed dwarfism in human beings, affecting more than 250,000 individuals worldwide. To the best of our knowledge, no study has reported a correlation between achondroplasia and aortic dissection. Here, we report a rare case of acute type A aortic dissection repair in a patient with achondroplasia.
    METHODS: An 82-year-old Japanese female with achondroplasia was admitted to our hospital because of acute-onset severe chest pain migration to her back accompanied by numbness and pain in the right lower limb. A computed tomography scan revealed acute type A aortic dissection with right leg ischemia because of an occlusion of the right common iliac artery. We successfully performed hemiarch repair.
    CONCLUSIONS: This report presents the first case of a patient at such an advanced age with dwarfism and cardiac surgery and the second case to illustrate successful acute aortic dissection repair in achondroplasia. Of note, all procedures were performed without specialized equipment. Overall, this report adds to the experience of successful cardiac surgery in this unique patient population.
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  • 文章类型: Case Reports
    Acute type A aortic dissection is a catastrophic situation, often accompanied by aortic regurgitation. A rarely described cause of aortic regurgitation, in this clinical scenario, is the prolapse of an intimal flap into the left ventricular outflow tract. We present here a case of acute type A aortic dissection with a circumferential intimal flap, prolapsing into the left ventricular outflow tract and causing massive aortic regurgitation.
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