目的:脑出血急性期早期活动与功能预后的关系已有报道,但是只有少数研究研究了脑出血急性期早期动员的抑制剂。本研究旨在研究早期动员的抑制剂。
方法:该研究纳入了322例脑出血患者。在早期动员小组中,动员在发病后72小时内开始,在延迟动员小组中,动员在发病后72小时或之后开始。使用单变量和多变量分析研究了动员开始时间与基线特征之间的关联,以阐明脑出血急性期早期动员的抑制剂。
结果:在病变部位观察到早期动员组和延迟动员组之间的显着差异,入院时白细胞计数,入院时中性粒细胞计数,入院时C反应蛋白水平,手术,使用机械通气,入院时的意识水平,血肿体积,血肿生长.在多元Logistic回归分析中,通过了五项,即,入学时意识水平低,帐篷下面的病变,手术,入院时C反应蛋白,血肿生长.
结论:在这项研究中,入学时意识水平低,帐篷下面的病变,手术,入院时C反应蛋白水平,血肿生长影响动员延迟。因此,建议通过对每个案例进行系统的循证评估来判断动员的开始时间。
OBJECTIVE: The association between early mobilization and functional prognosis in the acute phase of intracerebral hemorrhage has been reported, but only a few studies have investigated the inhibitors of early mobilization in the acute phase of intracerebral hemorrhage. This
study aimed to investigate the inhibitors of early mobilization.
METHODS: The
study enrolled 322 patients with intracerebral hemorrhage. In the early mobilization group, mobilization was started within 72 h from onset, and in the delayed mobilization group, mobilization was started at or after 72 h from onset. The association between the start of mobilization timing and baseline characteristics was investigated using univariate and multivariate analyses to clarify the inhibitors of early mobilization in the acute phase of intracerebral hemorrhage.
RESULTS: Significant differences between the early mobilization and delayed mobilization groups were observed in the lesion site, leukocyte count at admission, neutrophil count at admission, C-reactive protein level at admission, surgery, use of mechanical ventilation, consciousness level at admission, hematoma volume, and hematoma growth. In the multiple logistic regression analysis, five items were adopted, namely, low consciousness level at admission, lesion below the tent, surgery, C-reactive protein at admission, and hematoma growth.
CONCLUSIONS: In this
study, low consciousness level at admission, lesion below the tent, surgery, C-reactive protein level at admission, and hematoma growth affected delayed mobilization. Therefore, it is recommended to judge the start of mobilization timing by a systematic evidenced-based assessment for each case.