acute aortic syndrome

急性主动脉综合征
  • 文章类型: Case Reports
    起搏器植入后出血并发症构成风险,包括感染和住院时间延长。介绍了一例涉及植入过程中锁骨下静脉通路引起的主动脉壁内血肿(IMH)并伴有急性肺栓塞(PE)的病例。在目前的情况下,IMH可能是由于静脉穿刺和导丝推进过程中锁骨下动脉血管损伤所致,导致IMH和血胸。PE可能源于干预和IMH引起的血栓前状态。由于血液动力学稳定性和较高的手术风险,选择了采用连续CT扫描的保守管理。IMH和PE分辨率在随访中得到证实。
    Bleeding complications after pacemaker implantation pose risks, including infection and prolonged hospital stay. A case involving aortic intramural hematoma (IMH) arising from subclavian vein access during implantation and concomitant acute pulmonary embolism (PE) is presented. In the present case, IMH probably resulted from subclavian artery vasa vasorum trauma during vein puncture and guidewire advancement, leading to IMH and hemothorax. PE possibly stemmed from a prothrombotic state caused by the intervention and the IMH. Conservative management with serial CT scans was chosen due to hemodynamic stability and high surgical risk. IMH and PE resolution was confirmed at follow-up.
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  • 文章类型: Case Reports
    靶向血管内皮生长因子(VEGF)抑制剂途径的酪氨酸激酶抑制剂在治疗转移性肾癌方面显示出有希望的结果。然而,它们会增加患高血压和心血管并发症的风险。
    在这项研究中,我们报告了一例73岁的女性,她的4期肾细胞癌患者接受阿西替尼和派博利珠单抗治疗.她有顽固性胸痛和高收缩压,对阿片类药物没有反应。她的计算机断层扫描血管造影结果显示急性壁内血肿,降主动脉破裂。她接受了紧急胸主动脉腔内修复术。术后,她完全康复,没有任何神经或心血管问题。
    由于服用VEGF抑制剂和免疫疗法引起的心血管血流动力学并发症的严重程度,以及缺乏充分控制此类事件的抗高血压策略,需要对其心血管安全性进行明确和紧急的评估。该病例强调了心血管肿瘤学在处理此类急性主动脉灾难中的关键作用。
    UNASSIGNED: Tyrosine kinase inhibitors targeting the vascular endothelial growth factor (VEGF) inhibitor pathway with immune checkpoint blockade have shown promising outcomes in managing metastatic renal cancer. However, they increase the risk of a person developing high blood pressure and cardiovascular complications.
    UNASSIGNED: In this study, we report the case of a 73-year-old woman on axitinib and pembrolizumab for her Stage 4 renal cell carcinoma. She presented with intractable chest pain and high systolic blood pressure, not responding to opiates. Her computed tomography angiography results showed an acute intra-mural haematoma with a rupture in the descending thoracic aorta. She underwent emergency thoracic endovascular aortic repair. Post-operatively, she recovered fully without any neurological or cardiovascular issues.
    UNASSIGNED: The severity of cardiovascular haemodynamic complications arising from the consumption of VEGF inhibitors and from immunotherapy and the lack of anti-hypertensive strategies to adequately manage such events require an unequivocal and urgent assessment of their cardiovascular safety. This case highlights the crucial role of cardiovascular oncology in managing such acute aortic catastrophes.
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  • 文章类型: Case Reports
    A pulmonary artery periadventitial hematoma is a rare complication of a Stanford type A intramural hematoma. As the proximal ascending aorta and pulmonary artery share a common adventitial layer, extravasated blood from the intramural hematoma in the ascending thoracic aorta may extend to beneath the adventitia of the pulmonary artery. The authors describe a case involving a 66-year-old male with acute chest pain who presented with a pulmonary artery periadventitial hematoma associated with a Stanford type A intramural hematoma.
    폐동맥 외막주위 혈종은 Stanford A형 대동맥벽내 혈종의 드문 합병증이다. 근위부 상행 대동맥과 폐동맥은 공통된 혈관외막을 공유하고 있기 때문에 대동맥벽내 혈종의 혈액은 폐동맥으로 확산될 수 있다. 저자들은 급성 흉통을 호소하는 66세 남성에게서 보인 Stanford A형 대동맥벽내 혈종과 연관된 폐동맥 외막주위 혈종의 증례를 보고하고자 한다.
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  • 文章类型: Case Reports
    穿透性主动脉溃疡(PAU)是急性主动脉综合征的一个子集,其特征是高破裂风险和管理挑战。特别是在有显著合并症的老年患者中。该病例报告显示了一名75岁的患者,有冠状动脉旁路移植术(CABG)的病史,并且有多个PAU累及主动脉弓。认为不适合传统的开放手术。使用具有左锁骨下动脉(LSA)的预插管侧组件的分支主动脉内移植物来保持先前CABG的通畅性。对干预前后的主动脉配置进行了两次计算流体动力学(CFD)模拟和形态学分析,以评估LSA水平下流速和压降的变化以及管腔大小的差异。结果表明,干预后流量下降等于2.38%,压降增加4.48mmHg,而LSA横截面积和直径的最大差异为1.49cm2和0.64cm,分别。由于所选择的干预方法,LSA血流的最小改变证实了所选择的具有LSA保存的单体设计内移植物的有效性。确保心肌灌注。因此,CFD模拟证明是通过准确估计主要流体动力学参数来评估干预措施的血液动力学后果的强大工具。
    Penetrating aortic ulcer (PAU) represents a subset of acute aortic syndromes characterized by high rupture risk and management challenges, particularly in elderly patients with significant comorbidities. This case report showcases a 75-year-old patient with a history of coronary artery bypass graft (CABG) and with multiple PAUs involving the aortic arch, deemed unfit for conventional open surgery. A branched aortic endograft with a pre-cannulated side component for the left subclavian artery (LSA) was employed to preserve the patency of the previous CABG. Two computational fluid dynamics (CFD) simulations and a morphological analysis were performed on the pre- and post-intervention aortic configurations to evaluate changes in flow rate and pressure drop at LSA level and differences in the lumen size. The results revealed a decrease in the flow rate equal to 2.38% after the intervention and an increase in pressure drop of 4.48 mmHg, while the maximum differences in LSA cross-sectional areas and diameters were 1.49 cm2 and 0.64 cm, respectively. Minimal alteration in LSA blood flow due to the chosen intervention approach confirmed the effectiveness of the selected unibody design endograft with LSA preservation, ensuring myocardial perfusion. Therefore, CFD simulations demonstrate to be a powerful tool to evaluate the hemodynamic consequences of interventions by accurately estimating the main fluid dynamic parameters.
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  • 文章类型: Case Reports
    Valsalva动脉瘤窦患者的心源性卒中一例。病人主诉晕厥,说话含糊不清,口角向右侧偏离的历史,解决了一天。检查未发现局灶性神经功能缺损。脑CT显示左额叶皮层有腔隙性梗塞。超声心动图显示非冠状动脉尖的Valsalva动脉瘤窦。因此,考虑了继发于动脉瘤Valsalva窦中血栓的心脏栓塞性中风的诊断。这是罕见的Valsalva窦表现为心脏栓塞性中风。
    A case of cardioembolic stroke in a patient with sinus of Valsalva aneurysm. The patient presented with chief complaints of syncope, with slurring of speech and a history of deviation of angle of mouth to the right side, which resolved over one day. Examination revealed no focal neurological deficit. CT Brain revealed a lacunar infarct over the left frontal cortex. Echocardiography showed sinus of Valsalva aneurysm of the non-coronary cusp. Hence a diagnosis of cardioembolic stroke secondary to thrombus present in the sinus of Valsalva of the aneurysm was considered. This is a rare presentation of Sinus of Valsalva as a cardioembolic stroke.
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  • 文章类型: Case Reports
    护理点超声(PoCUS)可用于检测和评估急诊科(ED)可疑患者的动脉瘤和/或腹主动脉夹层。尽管常规使用PoCUS评估可疑主动脉瘤和夹层的腹主动脉,关于其在急诊急性腹主动脉闭塞诊断中的应用的文献有限.这是一个案例,证明了PoCUS在确定患有已知高血压和糖尿病的71岁女性患者中的急性主动脉闭塞中的用途。患者出现中央腹痛和双侧下肢无力至ED。患者有多种鉴别诊断,包括腹主动脉急性闭塞。主动脉的PoCUS用于诊断ED中的急性腹主动脉闭塞。快速诊断加快了转诊给血管外科医生以进行明确的治疗。急性腹主动脉闭塞是一种时间敏感且危及生命的紧急情况。腹主动脉的PoCUS以检测急性腹部闭塞可以快速诊断,并有可能改善预后。标准主动脉PoCUS扫描中应包括检测急性腹主动脉闭塞的方案。
    Point-of-care ultrasound (PoCUS) can be used to detect and evaluate for an aneurysm and/or a dissection of the abdominal aorta in suspected patients in the Emergency Department (ED). Despite the routine use of PoCUS for the assessment of the abdominal aorta in suspected aortic aneurysms and dissections, there is limited literature regarding its use in the diagnosis of acute abdominal aortic occlusions in the emergency setting. This is a case demonstrating the use of PoCUS in identifying an acute aortic occlusion in a 71-year-old female patient with known hypertension and diabetes mellitus. The patient presented with central abdominal pain and bilateral lower limb weakness to the ED. The patient had multiple differential diagnoses, including a possible acute aortic occlusion of the abdominal aorta. PoCUS of the aorta was utilized to diagnose an acute abdominal aortic occlusion in the ED. The rapid diagnosis expedited the referral to vascular surgeons for definitive management. Acute abdominal aortic occlusion is a time-sensitive and life-threatening emergency. PoCUS of the abdominal aorta to detect acute abdominal occlusions allows for a rapid diagnosis with the potential to improve outcomes. A protocol for detecting acute abdominal aortic occlusion should be included in the standard aorta PoCUS scan.
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  • 文章类型: Case Reports
    主动脉壁内血肿(AIH)是危及生命的紧急情况,涉及主动脉壁的完整性,其特征是血管直接破裂或位于主动脉壁中膜的动脉斑块自发出血。AIH和急性主动脉夹层之间的显著差异是没有内膜瓣,计算机断层扫描血管造影(CTA)上可辨别的发现。后续成像可以监测疾病进展或即将发生的并发症的早期发现。虽然有些患者可能需要手术干预,控制血压的医疗管理仍然是治疗的主要手段。我们的病例描述了一名患者,该患者被发现继发于心室纤颤,然后被发现在CTA上推测为斯坦福A型主动脉夹层。在检查完扫描后,由于没有内膜瓣,诊断被重新分类为AIH,然后,患者接受抗高血压药物治疗AIH.
    Aortic intramural hematoma (AIH) is a life-threatening emergency that involves aortic wall integrity and is characterized by either a direct rupture of the vasa vasorum or spontaneous bleeding of an arterial plaque located in the tunica media of the aortic wall. A notable difference between AIH and acute aortic dissection is the absence of an intimal flap, a finding discernable on computed tomography angiography (CTA). Follow-up imaging allows for the monitoring of disease progression or early findings of impending complications. While some patients may require surgical intervention, medical management with blood pressure control remains the mainstay in treatment. Our case describes a patient who was found to be in cardiac arrest secondary to ventricular fibrillation and was then found to have presumed Stanford Type A aortic dissection on CTA. After reviewing the scans, the diagnosis was reclassified to AIH due to the absence of an intimal flap, the patient was then managed medically for AIH with antihypertensive medications.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    右侧主动脉弓(RAArch)约占人群的0.1%。Kommerell憩室(KD),背侧主动脉弓的残余通常是指在异常左锁骨下动脉(ALSA)的起源处的动脉瘤性主动脉扩大,并且与主动脉夹层的风险增加相关.
    一名59岁的女性吸烟者,有高血压和高胆固醇血症史,有24小时的突然发作和严重的刺伤性胸痛放射到肩胛骨间区域。体格检查是正常的,除了双侧基底的蠕动。计算机断层扫描血管造影(CTA)显示RAArch中的B型主动脉夹层,由KD引起的ALSA,伴有主动脉周围血肿和血胸,无任何活动性造影剂外渗。医疗稳定后,使用右颈动脉-锁骨下搭桥术进行了半紧急混合修复,胸主动脉腔内修复术(TEVAR),左锁骨下动脉的栓塞,左臂严重缺血导致的左颈动脉-锁骨下分流术。术后CTA显示存在旁路,主动脉重塑,和ALSA水平的最小IIa型内漏。
    在B型夹层和KD患者中,包括TEVAR在内的混合修复术在对患者独特的解剖结构进行术前仔细评估后是可行的,与开放手术相比,可以降低术后发病率和死亡率.无症状的RAArch和KD患者可考虑预防性修复。
    UNASSIGNED: A right-sided aortic arch (RAArch) is present in approximately 0.1% of the population. A Kommerell\'s diverticulum (KD), a remnant of the dorsal aortic arch usually refers to an aneurysmal aortic enlargement at the origin of an aberrant left subclavian artery (ALSA) and is associated with an increased risk of aortic dissection.
    UNASSIGNED: A 59-year-old female smoker with a history of hypertension and hypercholesterolaemia presented with a 24-hour history of sudden-onset and severe stabbing chest pain radiating to the interscapular region. Physical examination was normal except for bilateral basal crepitations. Computed tomography angiography (CTA) showed a type B aortic dissection in a RAArch with an ALSA arising from KD with a peri-aortic haematoma and haemothorax without any active contrast extravasation. After medical stabilization, a semi-urgent hybrid repair was performed with a right carotid-subclavian bypass, thoracic endovascular aortic repair (TEVAR), a plug in the left subclavian artery, and left carotid-subclavian bypass due to severe ischaemia of the left arm. The postoperative CTA showed patent bypasses, aortic remodelling, and a minimal type IIa endoleak at the level of the ALSA.
    UNASSIGNED: In patients with a type B dissection and KD, hybrid repair including TEVAR is feasible after careful pre-operative assessment of the patient\'s unique anatomy and may reduce post-surgical morbidity and mortality compared to open surgery. Prophylactic repair may be considered in patients with an asymptomatic RAArch and KD.
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  • 文章类型: Case Reports
    主动脉肠瘘是一种危及生命的紧急情况,并伴有高发病率和死亡率。在动脉瘤破裂之前及时进行手术干预可将死亡率降低至约50%。主动脉肠瘘的潜在影像学模拟包括腹膜后纤维化,真菌性主动脉瘤,和感染性主动脉炎.与原发性相比,继发性主动脉肠瘘的发生率相对较高,并且开放式主动脉修复术与血管内支架修复术相比更为常见。动脉瘤囊中的异位气体和肠造影外渗到动脉瘤囊中可诊断为主动脉肠瘘。然而,由于上述发现极为罕见,因此不建议将肠造影用于主动脉肠常规评估.更常见的影像学发现包括肠环似乎粘附于动脉瘤囊,并在动脉瘤囊内或在肠和动脉瘤囊之间插入相关的炎性绞合和病灶或异位气体。在这里,我们介绍了一例52岁的男性,他出现了偶然的原发性主动脉肠瘘。
    Aortoenteric fistula is a life-threatening emergency and is associated with high morbidity and mortality. Prompt surgical intervention before the aneurysm ruptures lowers the mortality rate to about 50%. Potential imaging mimics for aortoenteric fistula include retroperitoneal fibrosis, mycotic aortic aneurysm, and infectious aortitis. Secondary aortoenteric fistula has relative higher incidence compared to primary and is more common with open aortic repair versus endovascular stent graft repair. Ectopic gas in the aneurysm sac and extravasation of enteric contrast into the aneurysm sac is diagnostic for aortoenteric fistula. However, enteric contrast is not recommended for routine evaluation of aortoenteric because the aforementioned finding is extremely rare. More common imaging findings include bowel loop appearing adherent to aneurysm sac with associated inflammatory stranding and foci or ectopic gas within the aneurysm sac or interposed between the bowel and aneurysm sac. Here we present a case of 52-year-old male who presents with incidental primary aortoenteric fistula.
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