abortion, induced

堕胎,诱导
  • 文章类型: Journal Article
    在2022年堕胎护理指南中,世界卫生组织(世卫组织)对7项法律和政策干预措施进行了系统的证据审查,以评估其对健康和社会的影响.为每个人提出了不同的建议。本文重点介绍了《指南》如何将堕胎法规重新概念化为一种复杂的结构性干预措施,该干预措施可以塑造临床护理和服务交付,并在这些系统以及定义它们的护理关系中分配风险和资源。然后提出指南建议并总结其证据基础,借鉴最近的法律和政策发展,强调其现实世界的意义。文章最后展望了堕胎法律和政策的未来,专注于服务提供创新和多样化的护理模式,药物监管和堕胎药的供应,以及在政治危机和迫切需要的背景下制定的保护性干预措施,这些干预措施服务于政策目标,并采取不同于过去的监管形式。
    In the 2022 Abortion Care Guideline, the World Health Organization (WHO) undertook systematic evidence reviews of seven law and policy interventions to assess their health and social impacts. Distinct recommendations were formulated for each. The present article highlights how the Guideline reconceptualizes abortion regulation as a complex structural intervention that shapes clinical care and service delivery and distributes risks and resources within these systems and in the care relations that define them. It then presents the Guideline recommendations and summarizes their evidence base, drawing on recent legal and policy developments to emphasize their real-world significance. The article concludes by anticipating the future of abortion law and policy, focusing on service delivery innovations and diverse care models, drug regulation and the supply of abortion pills, and protective interventions crafted in the context of political crisis and immediate need that serve policy objectives and take regulatory forms different from the past.
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  • 文章类型: Journal Article
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    文章类型: Journal Article
    五十年来,来自168项研究的压倒性证据表明,手术流产与随后的早产之间存在明显的剂量反应关系。2018年美国国家科学院报告仅考虑了这168项研究中的5项,代表了一个有偏见的样本,低估了手术流产与随后的早产之间的显着关联。本文件的目的是审查有关此效果的数据质量,回顾这种效应的大小,并对数据进行准确评估,以改善手术流产前的知情同意。
    Overwhelming evidence from 168 studies over fifty years points to a clear dose-response relationship between surgical abortion and subsequent preterm birth. The 2018 National Academy of Sciences report considered only five of these 168 studies and represents a biased sample that underreports a significant association between surgical abortion and subsequent preterm birth. The purpose of this document is to review the quality of the data on this effect, review the size of this effect, and portray an accurate assessment of the data to improve informed consent prior to surgical abortion.
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    文章类型: Journal Article
    来自五十年来168项研究的同行评审文献中的证据指出了一个因果关系,手术流产和随后早产之间的剂量反应关系。本文档提供了该文献的概述,讨论了这种效应的机制,证明了因果关系的证据的强度,并为手术流产前的知情同意提供指导。本文件未对手术流产和早产的研究质量进行详细的统计分析或高分辨率评估(实践指南11涵盖)。
    Evidence in peer-reviewed literature from 168 studies over fifty years points to a causal, dose-response relationship between surgical abortion and subsequent preterm birth. This document provides an overview of this literature, discusses mechanisms for this effect, demonstrates the strength of evidence for causality, and offers guidance for informed consent prior to surgical abortion. This document does not provide detailed statistical analysis or a high-resolution assessment of the quality of studies on surgical abortion and preterm birth (covered in Practice Guideline 11).
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    文章类型: Journal Article
    In October 2020, the Polish Constitutional Court held unconstitutional an exception in the Family Planning Act of 1993 that provided for legal abortion in cases of fetal abnormalities. This retrogressive step has led to an almost total ban on abortion in Poland. Drawing on existing Strasbourg case law and other relevant legal material, this paper attempts to anticipate a possible outcome of applications recently filed before the European Court of Human Rights by more than 1,000 Polish women who were denied abortions or who postponed their reproductive decisions out of fear. I focus on two factors that play a determining role in the adjudication of cases related to reproductive rights. The first one is a public interest in restricting abortion-namely, the \"protection of morals.\" The second is the margin of appreciation doctrine, which determines the degree of freedom that states enjoy in regulating certain issues, such as abortion, and which is highly dependent on the concept of a European consensus. I argue that this consensus-revealed through the domestic laws and practice of 47 Council of Europe member states-shows considerable unity and should thus restrict individual states\' discretion in limiting human rights and freedoms. The European Court of Human Rights, by acknowledging the relevance of a European consensus in abortion regulation, as well as evolving universal standards concerning reproductive rights, would avoid two pitfalls: one connected with analyzing the doubtful public interest in protecting morals, and another with a potential criticism of judicial activism and the court\'s imposition of its own moral evaluation of an abortion ban.
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  • 文章类型: Journal Article
    公共卫生专业人员,特别是州和地方卫生部门,并不总是清楚地了解他们与政治上有争议的公共卫生主题有关的角色。公共卫生专业人员之间的共识发展过程,认为最好的可用证据可能能够指导决策并制定适当的行动方案。
    2020年5月,一批在卫生部门工作的妇幼保健和计划生育专业人员,公共卫生学校的代表,和附属组织的成员聚集在一起,探讨与卫生部门参与堕胎相关的价值观和原则,并描述适合卫生部门的与堕胎相关的活动。召集会议遵循了一个结构化的共识过程,其中包括多轮输入以及反馈和修订的机会。
    召集参与者就指导参与与堕胎有关的活动的原则达成共识,一系列与堕胎有关的活动,适合卫生部门,以及支持开展此类活动的后续步骤。
    会议的经验表明,对于堕胎等有政治争议的公共卫生主题,共识程序是可行的。
    Public health professionals, particularly those in state and local health departments, do not always have clear understandings of their roles related to politically controversial public health topics. A process of consensus development among public health professionals that considers the best available evidence may be able to guide decision making and lay out an appropriate course of action.
    In May 2020, a group of maternal and child health and family planning professionals working in health departments, representatives of schools of public health, and members of affiliated organizations convened to explore values and principles relevant to health departments\' engagement in abortion and delineate activities related to abortion that are appropriate for health departments. The convening followed a structured consensus process that included multiple rounds of input and opportunities for feedback and revisions.
    Convening participants came to consensus on principles to guide engagement in activities related to abortion, a set of activities related to abortion that are appropriate for health departments, and next steps to support implementation of such activities.
    The experience of the convening indicates that consensus processes can be feasible for politically controversial public health topics such as abortion.
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  • 文章类型: Case Reports
    不确定生存能力的宫内妊娠是常见的,诊断早期妊娠丢失的指南必须平衡中断可行妊娠的风险与延迟诊断导致的焦虑和医学并发症。描述了两例可能的早期妊娠丢失,表现为不确定生存能力的宫内妊娠。与州生殖健康护理法规相关的护理可用性存在明显差异。繁重的堕胎限制,医学和社会耻辱,诊断标准中固有的发音干扰了临床判断的行使,并可能损害患者的身心健康。
    Intrauterine pregnancies of uncertain viability are common, and guidelines for diagnosing early pregnancy loss must balance the risk of interrupting a viable pregnancy with the anxiety and medical complications resulting from delayed diagnosis. Two cases of likely early pregnancy loss presenting as intrauterine pregnancies of uncertain viability are described, with stark differences in care availability related to state reproductive health care regulations. Onerous abortion restrictions, medical and societal stigma, and inherent pronatalism in diagnostic criteria interfere with the exercise of clinical judgment and can damage patients\' physical or mental health.
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  • 文章类型: Journal Article
    要开发最小数据集,被称为核心结果集,未来的流产随机对照试验。
    我们从堕胎研究的定量和定性系统评价中提取结果,以使用改良的德尔菲法进行评估。通过电子邮件,我们邀请了研究人员,临床医生,病人,和具有堕胎专业知识的医疗机构代表以9点Likert量表对结果的重要性进行评分。经过2轮,我们使用描述性分析来确定哪些结局符合预定义的共识标准.我们在一系列共识发展会议上最终确定了核心成果集。
    我们输入了42个结果,组织在15个领域,进入德尔福调查。251名受邀者中的118名(87%)对第一轮提供了答复(203份完整答复),218名受邀者中的118名(42%)完成了第二轮。16名专家参加了发展会议。最终结果集包括15个结果:10个结果适用于所有堕胎试验(成功堕胎,正在怀孕,死亡,出血,子宫感染,住院治疗,手术干预,疼痛,胃肠道症状,和患者的流产经验);2个结果仅适用于手术流产试验(子宫穿孔和宫颈损伤),一项仅适用于药物流产试验(子宫破裂);2项适用于评估麻醉流产的试验(过度镇静/呼吸抑制和局部麻醉全身毒性).
    使用强大的共识科学方法,我们为未来的堕胎研究开发了核心结果集。
    人工流产研究的标准化结果可以减少试验间的异质性,提高系统评价和临床指南的质量。研究人员应该选择,收集,并在未来的堕胎试验中报告这些核心结果。期刊编辑应倡导核心成果集报告。
    To develop a minimum data set, known as a core outcome set, for future abortion randomized controlled trials.
    We extracted outcomes from quantitative and qualitative systematic reviews of abortion studies to assess using a modified Delphi method. Via email, we invited researchers, clinicians, patients, and healthcare organization representatives with expertise in abortion to rate the importance of the outcomes on a 9-point Likert scale. After 2 rounds, we used descriptive analyses to determine which outcomes met the predefined consensus criteria. We finalized the core outcome set during a series of consensus development meetings.
    We entered 42 outcomes, organized in 15 domains, into the Delphi survey. Two-hundred eighteen of 251 invitees (87%) provided responses (203 complete responses) for round 1 and 118 of 218 (42%) completed round2. Sixteen experts participated in the development meetings. The final outcome set includes 15 outcomes: 10 outcomes apply to all abortion trials (successful abortion, ongoing pregnancy, death, hemorrhage, uterine infection, hospitalization, surgical intervention, pain, gastrointestinal symptoms, and patients\' experience of abortion); 2 outcomes apply to only surgical abortion trials (uterine perforation and cervical injury), one applies only to medical abortion trials (uterine rupture); and 2 apply to trials evaluating abortions with anesthesia (over-sedation/respiratory depression and local anesthetic systemic toxicity).
    Using robust consensus science methods we have developed a core outcome set for future abortion research.
    Standardized outcomes in abortion research could decrease heterogeneity among trials and improve the quality of systematic reviews and clinical guidelines. Researchers should select, collect, and report these core outcomes in future abortion trials. Journal editors should advocate for core outcome set reporting.
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