abnormalities

异常
  • 文章类型: Practice Guideline
    背景:关于处理阴茎大小异常和畸形恐惧症的建议对于指导循证临床实践非常重要。
    目的:介绍2023年欧洲泌尿外科性健康和生殖健康协会关于阴茎大小异常和畸形恐惧症管理的循证建议。
    方法:进行了广泛而全面的范围界定,涵盖了指南的所有领域。搜索的数据库包括Medline,EMBASE,和Cochrane图书馆.根据确定的证据为每个建议分配了证据水平和建议强度。2023年指南的证据截止日期为2022年6月1日。
    结果:结构良好的研究报告了高水平的证据,标准化的PROMS缺乏阴茎大小异常和畸形恐惧症。短阴茎/小阴茎的共同定义也缺乏。根据先天性对阴茎异常进行分类,收购,和畸形恐惧症的病因被认为是强制性的。详细的医疗和性精神病史以及阴茎大小的精确测量在诊断途径中至关重要。阴茎大小正常的患者寻求阴茎增强,应进行心理评估,以进行潜在的畸形恐惧症。阴茎长度和周长的增强可以通过多种治疗来实现,但是个性化的管理计划对于获得令人满意的结果至关重要。内分泌疗法,当指示时,仅在青春期前环境中有效。真空疗法在治疗方案中的证据基础有限,尽管据报道阴茎牵引治疗的结果可接受。增加阴茎长度和周长的手术技术证据有限,只能在广泛的患者咨询后提出。
    结论:阴茎异常和畸形恐惧症的管理是一个复杂的问题,有相当多的伦理问题。采用结构化的诊断和治疗途径至关重要,正如指南中所建议的那样。
    结果:在全球范围内,对增加阴茎大小的药物/手术治疗的要求急剧增加。几种保守和手术治疗是可用的。然而,很少有患者获得关于这些治疗的益处和可能的危害的明确信息.这些指南旨在提供一个结构化的路径,以指导医生和患者选择适当的治疗方法来增加阴茎大小。
    BACKGROUND: Recommendations regarding the management of penile size abnormalities and dysmorphophobia are important in guiding evidence-based clinical practice.
    OBJECTIVE: To present a summary of the 2023 European Association of Urology sexual and reproductive health evidence-based recommendations for the management of penile size abnormalities and dysmorphophobia.
    METHODS: A broad and comprehensive scoping exercise covering all areas of the guidelines was performed. Databases searched included Medline, EMBASE, and the Cochrane Libraries. A level of evidence and a strength of recommendation were assigned for each recommendation according to the evidence identified. The evidence cutoff date for the 2023 guidelines is June 1, 2022.
    RESULTS: Well-structured studies reporting high level of evidence, with standardized PROMS were deficient on penile size abnormalities and dysmorphohobia. A shared definition for short penis/micropenis was also lacking. Categorisation of penile abnormalities according to congenital, acquired, and dysmorphophobic aetiology is deemed compulsory. A detailed medical and psychosexual history and precise measurements of penile size are essential in the diagnostic pathway. Patients with normal penile size who are seeking penile augmentation should be referred for psychological evaluation for potential dysmorphophobic disorders. Penile length and girth enhancements can be achieved via a multitude of treatments, but a personalised management plan is crucial for satisfactory results. Endocrinological therapies, when indicated, are effective in the prepubertal setting only. Vacuum therapy has a limited evidence base in treatment protocols, although acceptable outcomes have been reported for penile traction therapy. Surgical techniques to enhance penile length and girth have limited evidence and should only be proposed after extensive patient counselling.
    CONCLUSIONS: Management of penile abnormalities and dysmorphophobia is a complex issue with considerable ethical concerns. The adoption of a structured diagnostic and therapeutic pathway is crucial, as recommended in the guidelines.
    RESULTS: Requests for medical/surgical treatments to increase penis size have increased dramatically worldwide. Several conservative and surgical treatments are available. However, few patients receive clear information on the benefits and possible harms of these treatments. These guidelines aim to provide a structured path to guide both physicians and patients in the selection of appropriate treatment(s) to increase penis size.
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