abdominal tb

腹部结核病
  • 文章类型: Case Reports
    结核病(TB)仍然是一个重大的全球卫生挑战。睫状结核是结核病的一种罕见表现,涉及感染的全身淋巴道传播,并且由于其通常无症状或非特异性而提出了诊断挑战。该病例报告记录了一名居住在美国的81岁的菲律宾裔美国男性中,罕见的胃肠道(GI)出血继发于没有肺部症状的粟粒性TB。广泛的影像学研究显示,右结肠有肿块,周围有多个出血血管;栓塞治疗是不可修正的,需要右半结肠切除术和末端回肠造口术。切除的肿块的病理报告显示,鳞茎结核伴坏死性肉芽肿和肉芽肿性淋巴结病,涉及23个淋巴结。患者开始接受抗结核医疗管理;然而,患者在临床上仍然不稳定,并在术后第39天过期.这个案例强调了在全球化时期和移民人口稠密的地区提高临床意识的重要性。我们旨在描述对胃肠道结核(GITB)的临床认识,并审查手术治疗的可能指征。我们的目标是帮助减少诊断延迟,因此改善患者的预后并限制疾病的传播。
    Tuberculosis (TB) remains a significant global health challenge. Miliary TB is a rare manifestation of TB that involves systemic lymphohematogenous dissemination of infection and presents diagnostic challenges due to its often asymptomatic or non-specific nature. This case report documents a rare occurrence of gastrointestinal (GI) bleeding secondary to miliary TB without pulmonary symptoms in an 81-year-old Filipino-American male living in the United States. Extensive imaging studies revealed a mass in the right colon with multiple bleeding vessels draped around it; it was not amendable to treatment with embolization and required right hemicolectomy with end ileostomy. The pathology report of the excised mass demonstrated miliary TB with necrotizing granulomas and granulomatous lymphadenopathy involving 23 lymph nodes. The patient was started on anti-tuberculosis medical management; however, the patient remained clinically unstable and expired on postoperative day 39. This case highlights the importance of the heightened clinical awareness required during times of globalization and in regions with dense immigrant populations. We aim to delineate the clinical understanding of gastrointestinal TB (GITB) and review possible indications for surgical management. We aim to help reduce diagnostic delay, therefore improving patient outcomes and limiting the spread of disease.
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  • 文章类型: Case Reports
    结核病(TB)是一种慢性肉芽肿性炎症性疾病,会影响我们身体的任何部位。结核病在发展中国家是一个重大问题。肠道TB占全球TB病例的2%。末端回肠和盲肠是两个常见的受累区域,因为淋巴组织丰富,生理停滞,有限的消化活动和增加的液体和电解质的吸收率。肠梗阻是肠结核的主要并发症,它的发生是因为肠腔狭窄,多发狭窄或粘连。肠TB和TB后肠梗阻患者的临床表现是非特异性的。它可以是急性的,慢性,或慢性急性。肠道结核的简单病例可以通过医学方式进行治疗。手术是为复杂的肠结核病例保留的,包括腹膜炎,肠梗阻和穿孔。这里,我们介绍一位37岁的男子,间歇性痉挛腹痛和呕吐。他被诊断为慢性部分小肠梗阻,可能继发于小肠癌。我们进行了节段性回肠切除和端对端回肠吻合术。术后,组织病理学结果是肠结核.此病例报告旨在使医生了解继发于肠道结核的小肠梗阻的罕见情况。临床医生需要对任何长期有部分梗阻症状的患者有很高的怀疑指数,一旦确诊就考虑手术和抗结核。
    Tuberculosis (TB) is a chronic granulomatous inflammatory disease that affects any part of our body. TB is a significant problem in developing countries. Intestinal TB accounts for 2% of TB cases worldwide. Terminal ileum and cecum are the two commonly affected regions because of abundant lymphoid tissue, physiologic stasis, limited digestive activity and increased fluid and electrolyte absorption rate. Intestinal obstruction is the leading complication of intestinal TB, and it occurs because of intestinal luminal narrowing, multiple strictures or adhesions. The clinical presentation of patients with intestinal TB and post-TB intestinal obstruction is non-specific. It can be acute, chronic, or acute on chronic. Uncomplicated cases of intestinal TB can be managed medically. Surgery is reserved for complicated cases of intestinal TB, which includes peritonitis, intestinal obstruction and perforations. Here, we present a 37-year-old man who presented with long-standing, intermittent crampy abdominal pain and vomiting. He was diagnosed with chronic partial small bowel obstruction secondary to possibly small bowel carcinoma. We did segmental ileal resection and end-to-end ileo-ileal anastomosis. Postoperatively, the histopathology result turned out to be intestinal TB. This case report aims to make physicians aware of the rare condition of small bowel obstruction secondary to intestinal TB. Clinicians need to have a high index of suspicion in any patient with long-standing symptoms of partial obstruction and consider surgery and anti-TB once diagnosed.
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  • 文章类型: Case Reports
    与腹膜结核相关的门静脉血栓形成是肺外结核的罕见表现。我们报告了一例有一年消化不良病史的33岁男性,一直服用质子泵抑制剂暂时缓解.鉴于持续的症状,做了内窥镜检查,最初显示十二指肠溃疡。间隔后重复内窥镜检查,有粘膜相关淋巴组织(MALT)淋巴瘤的证据,这促使对病人进行了大量的调查。正电子发射断层扫描(PET)扫描显示广泛的腹膜累及肝脏低密度病变,并在腹部CT扫描中出现门静脉血栓形成。肝病灶活检显示肉芽肿性炎症。面对诊断困境,最后,进行了腹腔镜活检,证实了腹膜结核合并门静脉血栓的诊断。该病例强调了在出现此类病例时保持高怀疑指数以包括结核病作为差异的重要性,并进行适当的调查以建立正确的诊断。
    Portal vein thrombosis associated with peritoneal tuberculosis is an uncommon manifestation of extrapulmonary tuberculosis. We report one such case of a 33-year-old male with a one-year history of dyspepsia, having been on proton pump inhibitors all this time with temporary relief. In view of ongoing symptoms, an endoscopy was done, which at first showed duodenal ulcer. On repeat endoscopy after an interval, there was evidence of mucosa-associated lymphoid tissue (MALT) lymphoma, which prompted a host of investigations in the patient. A positron emission tomography (PET) scan revealed extensive omento-peritoneal involvement along with a hypodense lesion in the liver with interval development of portal vein thrombosis on a CT scan of the abdomen. The biopsy of the hepatic lesion showed granulomatous inflammation. Faced with a diagnostic dilemma, finally, a laparoscopic biopsy was done, which confirmed the diagnosis of peritoneal TB with portal vein thrombosis. This case highlights the importance of keeping a high index of suspicion to include tuberculosis as a differential when presented with a case such as this and to conduct appropriate investigations to establish the correct diagnosis.
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  • 文章类型: Case Reports
    腹水被定义为腹腔中大量的液体,最常见的是肝硬化导致的门静脉高压症,急性肝功能衰竭,和心力衰竭。我们报告了一例腹水病例,其中一名39岁的男性出现在ED,主诉腹胀,上腹部散发的疼痛,在过去的两个月里无意中减肥,盗汗,和混血大便。我们进行了一些影像学检查和实验室研究,除了腹部CT造影外,没有发现任何重要的发现。在横结肠的长段显示大量腹水和粘膜下脂肪沉积,提示慢性炎症[可能是炎症性肠病(IBD)],网膜结块,和增厚。高度怀疑腹膜恶性肿瘤。进行了诊断/治疗性穿刺,通过它排出8升流体。还进行了细胞学检查,这显示主要是反应性间皮细胞,阴性抗酸杆菌(AFB)培养,和阴性聚合酶链反应(PCR)。我们还讨论了其他调查,这些都没有帮助确定诊断。
    Ascites is defined as a massive collection of fluid in the peritoneal cavity, and it is most commonly caused by portal hypertension due to liver cirrhosis, acute liver failure, and heart failure. We report a case of ascites in a 39-year-old male who presented to the ED complaining of abdominal distention, sporadic pain on the epigastric area, unintentional weight loss over the past two months, night sweats, and blood-mixed stool. We conducted several imaging investigations and laboratory studies and none of them revealed any significant findings except for the abdominal CT with contrast, which showed large ascites along with submucosal fat deposition in the long segment of the transverse colon, suggestive of chronic inflammation [probably inflammatory bowel disease (IBD)], omental caking, and thickening. Peritoneal malignancy was highly suspected. A diagnostic/therapeutic paracentesis was performed, through which 8 L of fluid was drained. Cytology was also performed and this showed mostly reactive mesothelial cells, negative acid-fast bacilli (AFB) culture, and negative polymerase chain reaction (PCR). We also discuss the other investigations performed, none of which helped in establishing a diagnosis.
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  • 文章类型: Journal Article
    艾滋病毒感染者(PLHIV)中结核病的比例很高。由于这种活跃的结核病病例发现被建议用于高结核病负担国家的艾滋病毒诊所。目前,痰液检查和胸部X线检查是建议用于HIV感染的结核病推定的一线检查。即使通过现有的程序性强化病例发现方案,PLHIV中经常发生的腹部结核病也可能被错过。这项研究评估了超声检查(USG)在HIV诊所中积极发现腹部结核病的常规应用。
    对印度一家结核病医院的HIV诊所8年数据进行回顾性分析。患者接受了胸部X光检查,痰液检查,进入艾滋病毒护理时的USG腹部和常规血液检查。病例表格被仔细检查以诊断结核病,USG发现和CD4细胞计数。腹部TB被分类为可能或可能的TB。可能的结核病是基于存在两个主要的USG(腹部)发现,提示活动性结核病。或一个主要的USG发现,至少有两个次要的USG发现或至少两个症状,或任何USG发现在另一个地点有微生物学证实的活动性结核病。可能的结核病是基于USG的一项主要发现,或存在两个轻微的USG发现,至少有两个症状。未获得细菌学证实。
    八百八十九人PLHIV接受了基线USG腹部。在HIV临床登记时,已经诊断出结核病的340例中有113例,在新诊断出结核病的91例中有87例患有腹部结核病。非腹部症状,比如体重减轻,53%的病例出现发烧和咳嗽,22%的病例根本没有症状。腹部淋巴结肿大伴中央区,腹膜炎,脾微凹陷,肠管增厚和肝脾肿大是这些病例的USG表现.
    腹部结核是PLHIV中常见的结核部位,表现为非腹部症状。它可以很容易地检测到的特征在一个简单的腹部超声。腹部USG应该是强化结核病病例发现算法的重要组成部分,用于生活在高结核病负担环境中的HIV感染者。
    High proportion of TB in people living with HIV (PLHIV) is undiagnosed. Due to this active TB case finding is recommended for HIV clinics in high TB burden countries. Presently sputum examination and chest radiography are frontline tests recommended for HIV infected TB presumptives. Abdominal TB which occurs frequently in PLHIV may be missed even by existing programmatic intensified case finding protocols. This study evaluated the routine use of ultrasonography (USG) for active case finding of abdominal TB in HIV clinics.
    Retrospective analysis of eight years\' data from an HIV Clinic in a TB hospital in India. Patients underwent chest x-ray, sputum examination, USG abdomen and routine blood tests at entry to HIV care. Case forms were scrutinized for diagnosis of TB, USG findings and CD4 cell counts. Abdominal TB was classified as probable or possible TB. Probable TB was based on presence of two major USG (abdomen) findings suggestive of active TB, or one major USG finding with at least two minor USG findings or at least two symptoms, or any USG finding with microbiologically confirmed active TB at another site. Possible TB was based on the presence of one major USG finding, or the presence of two minor USG findings with at least two symptoms. Bacteriological confirmation was not obtained.
    Eight hundred and eighty-nine people PLHIV underwent a baseline USG abdomen. One hundred and thirteen of 340 cases already diagnosed with TB and 87 of the 91 newly diagnosed with TB at time of HIV clinic registration had abdominal TB. Non-abdominal symptoms like weight loss, fever and cough were seen in 53% and 22% cases had no symptoms at all. Enlarged abdominal lymph nodes with central caseation, ascitis, splenic microabsesses, bowel thickening and hepatosplenomegaly were the USG findings in these cases.
    Abdominal TB is a frequent TB site in PLHIV presenting with non-abdominal symptoms. It can be easily detected on basis of features seen on a simple abdominal ultrasound. Abdominal USG should be essential part of intensified TB case finding algorithms for HIV infected people living in high TB burden settings.
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  • 文章类型: Journal Article
    BACKGROUND: The case series presented here demonstrates that the pathology encountered during inguinal hernia repair can often provide clues to concurrent pathology; the well trained surgeon\'s broader medical knowledge can lead to earlier diagnosis.
    METHODS: The case series examines four cases of men presenting with inguinal hernias, who were found to have concurrent abdominal pathology after further investigation of the intraoperative findings of the surgeon.
    CONCLUSIONS: Operating surgeons not only require the necessary surgical skills to deal with the unexpected, but must also rely on their ability to think laterally when interpreting atypical incidental findings during \'routine\' procedures.
    CONCLUSIONS: Experience and knowledge gained through a surgeon\'s career is essential to enable them to correctly interpret their intraoperative findings and potentially diagnose concurrent pathology. The authors believe that surgical care practitioners, trained in just 2 years, would lack these essential skills.
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