Wasting

浪费
  • 文章类型: Case Reports
    由于广泛的畜牧业对猪肉的需求不断增加,猪的蠕虫感染重新获得了临床和经济意义。猪感染猪鞭虫可导致消瘦和腹泻。常规育肥场的临床毛虫病病例证明了这一点,猪被放在牧场上。虽然所有的预育肥猪,还没有在牧场上,有良好的身体状况和坚硬的粪便,在牧场上饲养的育肥猪中约有一半出现腹泻和身体状况不佳。使用粪便浮选研究从所有动物中直接收集的粪便样品。在32个粪便样本中的17个中检测到大量猪链球菌卵,而所有来自预育肥猪的样本均为阴性。每克粪便的鸡蛋数量最高,为778,000。在粪便浮选中,三个环境样品中的两个也对猪链球菌呈阳性。这个案例表明猪链球菌必须被认为是饲养在牧场上的猪的肠病原体,作为有利的环境条件,缺乏从牧场上清除粪便会导致猪周围大量感染卵的积累。
    Helminth infections of swine regain clinical and economic importance due to the increasing demand for pork from extensive husbandry. Infections with Trichuris suis in pigs can lead to wasting and diarrhoea. This was demonstrated by a case of clinical trichurosis on a conventional fattening farm, where pigs were kept on pasture. While all pre-fattening pigs, which had not been on the pasture yet, had a good body condition and firm faeces, diarrhoea and poor body condition were observed in approximately half of the fattening pigs kept on pasture. Rectally collected faecal samples from all animals were investigated using faecal flotation. High numbers of T. suis eggs were detected in 17 out of 32 faecal samples, while all samples from pre-fattening pigs were negative. The highest number of eggs per gram of faeces was 778,000. Two out of three environmental samples were also positive for T. suis in faecal flotation. This case demonstrates that T. suis must be considered as an enteropathogen in pigs kept on pasture, as favourable environmental conditions, and the lack of removal of faeces from a pasture can lead to the accumulation of large numbers of infective eggs in the pigs\' surroundings.
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  • 文章类型: Journal Article
    背景:难民儿童中的浪费仍然是一个严重的公共卫生问题,特别是在冲突和流离失所的情况下。难民背景下风险因素的证据对于成功预防营养不良及其后果至关重要。然而,关于在难民环境中浪费的决定因素知之甚少。因此,这项研究旨在确定Okugo难民营南苏丹6至59个月大的儿童消瘦的决定因素,埃塞俄比亚西南部。
    方法:2019年4月6日至5月2日,对99名急性营养不良儿童(病例)和297名非营养不良儿童(对照)进行了基于机构的无匹配病例对照研究。通过系统随机抽样选择研究参与者,并使用结构化问卷通过面对面访谈收集有关暴露变量的数据。将数据输入到Epi数据版本3.1中,并导出到SPSS版本25中进行进一步分析。描述性的,双变量,并进行了多变量分析,以计算汇总统计数据并确定浪费的决定因素。
    结果:病例和对照组的平均年龄分别为13.8(±6.9)和19.2(±8.7)个月,分别。多变量分析显示,无法读写的母亲(调整后的比值比=3.26,95%置信区间(1.07-7.93)),父亲唯一的决策者在家庭中使用捐赠项目(调整后的优势比=3.75,95%置信区间(1.28-10.85)),未使用所有捐赠的难民食品和非食品项目(调整后的比值比=2.57;95%置信区间(1.17-5.66)),调查前2周的腹泻发生率(调整后的比值比=5.28,95%置信区间(2.31-12.04)),和母亲的吸烟习惯(调整比值比=2.98,95%置信区间(1.19-7.44))是消瘦的显著决定因素。
    结论:研究结果表明,不能读写的母亲,父亲唯一的决策者,父母吸烟习惯,不使用所有捐赠的难民食品,腹泻病被发现是消瘦的独立决定因素。因此,对急性营养不良的干预措施,重点是通过培训和加强对家庭资产的控制来增强妇女的权能,正确利用捐赠的食物,非食品项目将发挥至关重要的作用。
    BACKGROUND: Wasting among refugee children continues to be a serious public health problem particularly in conflict and in situations when people are displaced. Evidence of risk factors in the refugee context is crucial to successfully prevent malnutrition and its consequences. However, little information is known about the determinants of wasting in a refugee setting. Hence, this study was aimed to identify determinants of wasting among South Sudanese 6- to 59-month-old children in Okugo refugee camp, South-Western Ethiopia.
    METHODS: Institutional-based unmatched case-control study was conducted on 99 acute malnutrition children (cases) and 297 children who are not malnourished (control) from 6 April to 2 May 2019. The study participant was selected by systematic random sampling and data on exposure variables were collected by face-to-face interview using a structured questionnaire. Data were entered into Epi data version 3.1 and was exported to SPSS version 25 for further analysis. Descriptive, bivariable, and multivariable analyses were done to compute summary statistics and to identify determinants of wasting.
    RESULTS: The mean age of the cases and controls with standard deviation (SD) was 13.8 (±6.9) and 19.2 (±8.7) months, respectively. Multi-variable analysis revealed that mothers who were unable to read and write (adjusted odds ratio = 3.26, 95% confidence interval (1.07-7.93)), fathers only decision-maker to use donations items in the household (adjusted odds ratio = 3.75, 95% confidence interval (1.28-10.85)), not used all donated refugee food and non-food items (adjusted odds ratio = 2.57; 95% confidence interval (1.17-5.66)), the incidence of diarrhea 2 weeks preceding the survey (adjusted odds ratio = 5.28, 95% confidence interval (2.31-12.04)), and mother\'s smoking habit (adjusted odds ratio = 2.98, 95% confidence interval (1.19-7.44)) were significant determinants of wasting.
    CONCLUSIONS: The finding shows that mothers who are unable to read and write, father only decision-maker, parents\' smoking habit, not using all donated refugee food items, and diarrheal disease were found to be independent determinants of wasting. Hence, interventions on acute malnutrition which are focused on empowering women through training and strengthening their control over the household assets, proper utilization of donated food, and non-food items will play a paramount role.
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  • 文章类型: Journal Article
    BACKGROUND: One newly proposed approach to determining eligibility of children aged 6-59 months for therapeutic feeding programs (TFPs) is to use mid-upper arm circumference (MUAC) < 115 mm, bilateral oedema or Weight-for-Age Z-score (WAZ) < - 3 as admission criteria (MUAC+SWAZ). We explored potential consequences of this approach on the eligibility for treatment, as compared with the existing WHO normative guidance. We also compared sensitivity and specificity parameters of this approach for detecting wasted children to the previously described \"Expanded MUAC\" approach.
    METHODS: We analyzed data from 558 population representative cross-sectional cluster surveys conducted since 2007. We retrieved all children classified as severe acute malnutrition (SAM), moderate acute malnutrition (MAM), and those who are both wasted and stunted (WA + ST), and calculated proportions of previously eligible children who would now be excluded from treatment, as well as proportions of non-malnourished children among those who would become eligible. We also analyzed the expected changes in the number and demographics (sex, age) of the selected populations of children according to the different admission approaches.
    RESULTS: Both MUAC+SWAZ and Expanded MUAC case detection approaches substantially increase the sensitivity in detecting SAM, as compared to an approach which restricts detection of SAM cases to MUAC< 115 mm and oedema. Improved sensitivity however is attained at the expense of specificity and would require a very large increase of the size of TFPs, while still missing a non-negligible proportion (20-25%) of the SAM caseload. While our results confirm the sensitivity of the MUAC+SWAZ case detection approach in detecting WA + ST (over 80%), they show, on the other hand, that about half of the additional target detected by using SWAZ criterion will be neither SAM nor WA + ST.
    CONCLUSIONS: These results suggest that recently promoted approaches to case detection inflate TFPs\' targets through the allocation of treatment to large numbers of children who have not been shown to require this type of support, including a significant proportion of non-acutely malnourished children in the MUAC+SWAZ approach. Considering the scarcity of resources for the implementation of TFPs, the rationale of abandoning the use of WHZ and of these alternative case detection strategies need to be critically reviewed.
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  • 文章类型: Journal Article
    营养不良仍然是发展中国家的主要公共卫生问题,特别是在5岁以下的儿童中,这些儿童更容易受到宏观和微观营养素缺乏的影响。对埃塞俄比亚儿童的营养状况进行了各种系统评价和荟萃分析(SRM)研究,但是没有对该主题的发现进行总结。因此,本综述旨在总结来自SRM研究的关于埃塞俄比亚5岁以下儿童营养不良和不良喂养方式的严重程度和决定因素的证据.
    PubMed,Embase,Scopus,WebofSciences,Cochrane系统评价数据库,效果评论摘要数据库,和GoogleScholar进行了关于埃塞俄比亚营养不良程度和危险因素以及儿童喂养实践指标的SRM研究。使用多重系统评价(AMSTAR)工具评估纳入研究的方法学质量。纳入的SRM研究对发育迟缓的患病率和决定因素的估计,浪费,体重不足,和不良的儿童喂养习惯被汇总并使用随机效应荟萃分析模型进行总结。
    我们纳入了9项SRM研究,包含255项观察研究中的214,458名5岁以下儿童。发育迟缓患病率的汇总估计,体重不足,消瘦率42%(95CI=37-46%),33%(95CI=27-39%),和15%(95CI=12-19%),分别。符合及时开始母乳喂养建议的儿童比例,头6个月纯母乳喂养,及时开始补充喂养的比例分别为65%、60%和62%,分别。满足饮食多样性和进餐频率建议的儿童比例分别为20和56%,分别。只有10%的儿童符合可接受饮食的最低标准。不良的喂养方式和营养不良状况之间有着密切的关系,这两种情况都与各种健康有关,社会经济,和环境因素。
    儿童营养不良和不良喂养方式在埃塞俄比亚非常普遍,并引起重大公共卫生问题。只有少数孩子得到适当的补充喂养。需要多部门的努力来改善儿童的喂养方式,减少该国营养不良的沉重负担。
    Malnutrition remains to be a major public health problem in developing countries, particularly among children under-5 years of age children who are more vulnerable to both macro and micro-nutrient deficiencies. Various systematic review and meta-analysis (SRM) studies were done on nutritional statuses of children in Ethiopia, but no summary of the findings was done on the topic. Thus, this umbrella review was done to summarize the evidence from SRM studies on the magnitude and determinants of malnutrition and poor feeding practices among under-5 children in Ethiopia.
    PubMed, Embase, Scopus, Web of Sciences, Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, and Google Scholar were searched for SRM studies on magnitude and risk factors of malnutrition and child feeding practice indicators in Ethiopia. The methodological quality of the included studies was assessed using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. The estimates of the included SRM studies on the prevalence and determinants of stunting, wasting, underweight, and poor child feeding practices were pooled and summarized with random-effects meta-analysis models.
    We included nine SRM studies, containing a total of 214,458 under-5 children from 255 observation studies. The summary estimates of prevalence of stunting, underweight, and wasting were 42% (95%CI = 37-46%), 33% (95%CI = 27-39%), and 15% (95%CI = 12-19%), respectively. The proportion of children who met the recommendations for timely initiation of breastfeeding, exclusive breastfeeding during the first 6 months, and timely initiation of complementary feeding were 65, 60, and 62%, respectively. The proportion of children who met the recommendations for dietary diversity and meal frequency were 20, and 56%, respectively. Only 10% of children fulfilled the minimum criteria of acceptable diet. There was a strong relationship between poor feeding practices and the state of malnutrition, and both conditions were related to various health, socio-economic, and environmental factors.
    Child malnutrition and poor feeding practices are highly prevalent and of significant public health concern in Ethiopia. Only a few children are getting proper complementary feeding. Multi-sectoral efforts are needed to improve children\'s feeding practices and reduce the high burden of malnutrition in the country.
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  • 文章类型: Journal Article
    我们评估了同时浪费和发育不良(WaSt)的患病率,并探讨了浪费之间的重叠。发育不良,在Karamoja,6-59个月的儿童中,体重不足和中上臂围(MUAC)低,乌干达。我们还确定了用于检测WaSt的最佳年龄体重(WAZ)和MUAC阈值。我们使用Karamoja的2015-2018年食品安全和营养评估(FSNA)横断面调查数据集进行了二次数据分析。浪费,使用WHO生长标准将发育迟缓和体重不足定义为<-2.0z评分。低MUAC定义为<12.5cm。我们将WaSt定义为同时消瘦和发育迟缓。WaSt的患病率为4.96%(95%CI[4.64,5.29])。WaSt在瘦肉季节比收获季节更普遍(5.21%vs.4.53%;p=.018)。大约一半(53.92%)的WaSt儿童的MUAC较低,所有人都体重不足。年龄小于36个月的年幼儿童有更多的WaSt,尤其是男性。WaSt的男性MUAC中位数高于女性(12.50vs.12.10cm;p<.001)。WAZ<-2.60阈值以优异的灵敏度(99.02%)和高特异性(90.71%)检测到WaSt。MUAC阈值<13.20cm对检测WaSt具有良好的灵敏度(81.58%)和中等的特异性(76.15%)。鉴于其高死亡风险。所有患有WaSt的儿童体重不足,一半的MUAC较低。WAZ和MUAC可能是检测WaSt的有用工具。建议对WaSt检测的WAZ和MUAC截止值进行患病率监测和前瞻性研究。建议将来考虑将WAZ纳入治疗性喂养计划,以检测和治疗WaSt儿童。
    We assessed prevalence of concurrently wasted and stunted (WaSt) and explored the overlaps between wasted, stunted, underweight and low mid-upper arm circumference (MUAC) among children aged 6-59 months in Karamoja, Uganda. We also determined optimal weight-for-age (WAZ) and MUAC thresholds for detecting WaSt. We conducted secondary data analysis with 2015-2018 Food Security and Nutrition Assessment (FSNA) cross-sectional survey datasets from Karamoja. Wasting, stunting and underweight were defined as <-2.0 z-scores using WHO growth standards. Low MUAC was defined as <12.5 cm. We defined WaSt as concurrent wasting and stunting. Prevalence of WaSt was 4.96% (95% CI [4.64, 5.29]). WaSt was more prevalent in lean than harvest season (5.21% vs. 4.53%; p = .018). About half (53.92%) of WaSt children had low MUAC, and all were underweight. Younger children aged <36 months had more WaSt, particularly males. Males with WaSt had higher median MUAC than females (12.50 vs. 12.10 cm; p < .001). A WAZ <-2.60 threshold detected WaSt with excellent sensitivity (99.02%) and high specificity (90.71%). MUAC threshold <13.20 cm had good sensitivity (81.58%) and moderate specificity (76.15%) to detect WaSt. WaSt prevalence of 5% is a public health concern, given its high mortality risk. All children with WaSt were underweight and half had low MUAC. WAZ and MUAC could be useful tools for detecting WaSt. Prevalence monitoring and prospective studies on WAZ and MUAC cut-offs for WaSt detection are recommended. Future consideration to integrate WAZ into therapeutic feeding programmes is recommended to detect and treat WaSt children.
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  • 文章类型: Journal Article
    当身高体重Z评分(WHZ)研究了不同病例负荷和死亡率对入院儿童死亡比例的影响。我们使用相同的计算来估计所有SAM相关死亡的比例,这些死亡将被排除在48个国家的MUAC-only政策中,只有MUAC对SAM的相对病例负荷非常不同,只有WHZ和两个缺陷的孩子。病死率(CFR)取自模拟,实证数据和文献。
    仅MUAC的相对SAM病例数,仅WHZ和具有两种标准的WHZ对所有SAM相关死亡的比例具有主要影响,这些死亡将在仅接受MUAC治疗的儿童中发生。许多国家,尤其是在萨赫勒地区,如果仅实施MUAC计划,西非和东南亚将无法确定与SAM相关的大多数死亡人数。全球范围内,在我们的分析中,被排除在治疗范围之外的儿童中,估计每年的最低死亡人数为30万.
    数字,随着现行政策的任何变化,被排除在治疗之外的儿童的比例或归因分数是指导政策变化的正确指标。不应单独使用CRF来指导政策选择是否放弃WHZ作为SAM的诊断。所有诊断营养不良的标准都需要保留。找到识别低WHZ儿童的方法至关重要,但不是低MUAC,在社区中,这样他们就不会不被发现。
    Severe acute malnutrition (SAM) is diagnosed when the weight-for-height Z-score (WHZ) is <-3Z of the WHO2006 standards, or a mid-upper-arm circumference (MUAC) of < 115 mm or there is nutritional oedema. Although there has been a move to eliminate WHZ as a diagnostic criterion we have shown that children with a low WHZ have at least as high a mortality risk as those with a low MUAC. Here we take the estimated case fatality rates and published case-loads to estimate the proportion of total SAM related deaths occurring in children that would be excluded from treatment with a MUAC-only policy.
    The effect of varying case-load and mortality rates on the proportion of all deaths that would occur in admitted children was examined. We used the same calculations to estimate the proportion of all SAM-related deaths that would be excluded with a MUAC-only policy in 48 countries with very different relative case loads for SAM by only MUAC, only WHZ and children with both deficits. The case fatality rates (CFR) are taken from simulations, empirical data and the literature.
    The relative number of cases of SAM by MUAC alone, WHZ alone and those with both criteria have a dominant effect on the proportion of all SAM-related deaths that would occur in children excluded from treatment by a MUAC-only program. Many countries, particularly in the Sahel, West Africa and South East Asia would fail to identify the majority of SAM-related deaths if a MUAC only program were to be implemented. Globally, the estimated minimum number of deaths that would occur among children excluded from treatment in our analyses is 300,000 annually.
    The number, proportion or attributable fraction of children excluded from treatment with any change of current policy are the correct indicators to guide policy change. CRFs alone should not be used to guide policy in choosing whether or not to drop WHZ as a diagnostic for SAM. All the criteria for diagnosis of malnutrition need to be retained. It is critical that methods are found to identify those children with a low WHZ, but not a low MUAC, in the community so that they will not remain undetected.
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