背景:椎体血管瘤(VHs)是最常见的脊柱良性肿瘤,在常规脊柱成像过程中经常偶然发现。
方法:从2005年1月至2023年9月,对我们机构的住院和门诊医院记录进行了回顾性审查,以诊断VHs。搜索过滤器包括“椎体血管瘤,\"\"背痛,\"\"弱点,神经根病,“和”局灶性神经功能缺损。“这些患者的影像学评估包括X线平片,CT,MRI。在确认VH的诊断后,这些图像用于生成本手稿中使用的图形。此外,使用PubMed对手稿的文献综述部分进行了广泛的文献检索.
结果:VHs是良性血管增生,可引起脊柱椎体骨小梁的重塑。水平小梁恶化,导致垂直小梁增厚,在矢状磁共振成像(MRI)和计算机断层扫描(CT)上出现条纹状外观,“灯芯绒标志,“和轴向成像上的点状外观,\"波尔卡圆点标志。由于病变的血管脂肪比例低,这些发现见于典型的椎体血管瘤。相反,非典型椎体血管瘤可能会或可能不会出现“灯芯绒”或“波尔卡圆点”征象,原因是脂肪含量较低,血管成分较高。非典型椎体血管瘤常模仿其他肿瘤病理,诊断具有挑战性。尽管大多数VHs是无症状的,由于神经根和/或脊髓压迫,侵袭性椎体血管瘤可出现神经系统后遗症,如脊髓病和神经根病。无症状椎体血管瘤不需要治疗,对于引起疼痛的椎体血管瘤有很多治疗选择,神经根病,和/或脊髓病。手术(全身切除术,椎板切除术),经皮技术(椎体成形术,硬化疗法,栓塞),和放射治疗可以适当组合或单独使用。具体的治疗方案取决于病变的大小/位置和神经元压迫程度。对于有症状的椎体血管瘤患者的最佳治疗方案尚无共识,尽管已经提出了管理算法。
结论:虽然典型的椎体血管瘤诊断相对简单,对于非典型和侵袭性病变的鉴别诊断很广泛。关于管理有症状病例的最佳方法正在进行辩论,然而,手术切除通常被认为是神经功能缺损患者的一线治疗。
BACKGROUND: Vertebral hemangiomas (VHs) are the most common benign tumors of the spinal column and are often encountered incidentally during routine spinal imaging.
METHODS: A retrospective
review of the inpatient and outpatient hospital records at our institution was performed for the diagnosis of VHs from January 2005 to September 2023. Search filters included \"vertebral hemangioma,\" \"back pain,\" \"weakness,\" \"radiculopathy,\" and \"focal neurological deficits.\" Radiographic evaluation of these patients included plain X-rays, CT, and MRI. Following confirmation of a diagnosis of VH, these images were used to generate the figures used in this manuscript. Moreover, an extensive literature search was conducted using PubMed for the literature
review portion of the manuscript.
RESULTS: VHs are benign vascular proliferations that cause remodeling of bony trabeculae in the vertebral body of the spinal column. Horizontal trabeculae deteriorate leading to thickening of vertical trabeculae which causes a striated appearance on sagittal magnetic resonance imaging (MRI) and computed tomography (CT), \"Corduroy sign,\" and a punctuated appearance on axial imaging, \"Polka dot sign.\" These findings are seen in \"typical vertebral hemangiomas\" due to a low vascular-to-fat ratio of the lesion. Contrarily, atypical vertebral hemangiomas may or may not demonstrate the \"Corduroy\" or \"Polka-dot\" signs due to lower amounts of fat and a higher vascular component. Atypical vertebral hemangiomas often mimic other neoplastic pathologies, making diagnosis challenging. Although most VHs are asymptomatic, aggressive vertebral hemangiomas can present with neurologic sequelae such as myelopathy and radiculopathy due to nerve root and/or spinal cord compression. Asymptomatic vertebral hemangiomas do not require therapy, and there are many treatment options for vertebral hemangiomas causing pain, radiculopathy, and/or myelopathy. Surgery (corpectomy, laminectomy), percutaneous techniques (vertebroplasty, sclerotherapy, embolization), and radiotherapy can be used in combination or isolation as appropriate. Specific treatment options depend on the lesion\'s size/location and the extent of neural element compression. There is no consensus on the optimal treatment plan for symptomatic vertebral hemangioma patients, although management algorithms have been proposed.
CONCLUSIONS: While typical vertebral hemangioma diagnosis is relatively straightforward, the differential diagnosis is broad for atypical and aggressive lesions. There is an ongoing debate as to the best approach for managing symptomatic cases, however, surgical resection is often considered first line treatment for patients with neurologic deficit.