Vascular Fistula

血管瘘
  • 文章类型: Journal Article
    未能成熟和早期狭窄仍然是Achille血液透析动静脉瘘(AVF)产生的足跟。AVF的成熟和通畅性可能受到各种人口统计学的影响,合并症,和解剖学因素。本研究旨在回顾具有各种风险评分和机器学习模型的AVF成熟和通畅的预测模型。
    文献检索在PubMed上进行,Scopus,和Embase来识别合格的文章。使用偏见风险评估预测模型(PROBAST)工具评估研究的质量。提取了纳入研究的性能(辨别和校准)。
    14项研究(7项研究使用风险评分方法;7项研究使用机器学习方法)被纳入综述。其中,12项研究被评为偏倚风险高或不清楚。“六项研究被评为高度关注或适用性不明确。在5项使用风险评分方法(0.70-0.886)和3项使用机器学习方法(0.80-0.85)的研究中报告了C统计(模型判别度量)。在三项研究中报告了模型校准。其中一项研究开发的失败到成熟的风险评分已在三个不同的患者人群中进行了外部验证,然而,模型判别显着下降(C统计量:0.519-0.53)。
    AVF成熟/通畅性的现有预测模型的性能被低估。他们在自己的研究人群中表现出令人满意的表现。然而,用于建立一些模型的方法存在较高的偏差风险.审查的模型也缺乏外部验证或在外部队列中表现降低。
    UNASSIGNED: Failure-to-mature and early stenosis remains the Achille\'s heel of hemodialysis arteriovenous fistula (AVF) creation. The maturation and patency of an AVF can be influenced by a variety of demographic, comorbidity, and anatomical factors. This study aims to review the prediction models of AVF maturation and patency with various risk scores and machine learning models.
    UNASSIGNED: Literature search was performed on PubMed, Scopus, and Embase to identify eligible articles. The quality of the studies was assessed using the Prediction model Risk Of Bias ASsessment (PROBAST) Tool. The performance (discrimination and calibration) of the included studies were extracted.
    UNASSIGNED: Fourteen studies (seven studies used risk score approaches; seven studies used machine learning approaches) were included in the review. Among them, 12 studies were rated as high or unclear \"risk of bias.\" Six studies were rated as high concern or unclear for \"applicability.\" C-statistics (Model discrimination metric) was reported in five studies using risk score approach (0.70-0.886) and three utilized machine learning methods (0.80-0.85). Model calibration was reported in three studies. Failure-to-mature risk score developed by one of the studies has been externally validated in three different patient populations, however the model discrimination degraded significantly (C-statistics: 0.519-0.53).
    UNASSIGNED: The performance of existing predictive models for AVF maturation/patency is underreported. They showed satisfactory performance in their own study population. However, there was high risk of bias in methodology used to build some of the models. The reviewed models also lack external validation or had reduced performance in external cohort.
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  • 文章类型: Case Reports
    颈动脉海绵窦瘘(CCF)的三个典型症状是搏动性眼球突出,瘀伤和结膜化学。这里,我们介绍了一个84岁女性由于高流量CCF引起的孤立的外展神经麻痹的临床病例,没有典型的充血性眼性特征。这是一个诊断挑战,因为,对于50岁以上有心血管危险因素的患者,缺血性单神经病是最常见的病因。这种情况说明了最不常见的CCF类型,很容易被误诊。即使没有经典的三联征,医生也应将瘘管视为孤立的外展神经麻痹患者的可能诊断。
    The three classic symptoms of carotid cavernous fistula (CCF) are pulsating exophthalmos, bruit and conjunctival chemosis. Here, we present a clinical case of isolated abducens nerve palsy due to a high-flow CCF in an 84-year-old woman, without the typical congestive orbito-ocular features. It was a diagnostic challenge because, for patients older than 50 years with cardiovascular risk factors, ischaemic mononeuropathy is the most frequent aetiology. This case illustrates the least common type of CCF that can be easily misdiagnosed. Physicians should consider fistula as a possible diagnosis in a patient with isolated abducens nerve palsy even without the classic triad.
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  • 文章类型: Review
    背景:主动脉食管瘘(AEF)是一种极其罕见且高度致命的并发症,导致高发病率和死亡率。文献中很少报道食管癌切除术后AEF的成功治疗。
    方法:这里我们介绍一例罕见的44岁女性食管癌切除术后出现AEF并发症的病例,主要表现为血液的呕吐。胸部计算机断层扫描和计算机断层扫描血管造影均显示双侧胸腔积液和肺不张,而胃镜检查显示消化道大出血。急诊手术包括切除纵隔脓肿,左下肺楔形切除术,胸主动脉腔内修复术(TEVAR),其次是支持性治疗。手术成功了,出院后随访1年,恢复良好。我们还回顾了以前的历史文献,原因,病理生理学,临床表现,诊断,食管腺癌术后AEF的治疗。
    结论:在我们的案例中,开胸联合TEVAR治疗食管腺癌术后AEF疗效确切。该病例为食管癌术后AEF的临床诊断和治疗提供了成功经验。
    BACKGROUND: Aortoesophageal fistula (AEF) is an extremely rare and highly fatal complication leading to a high risk of morbidity and mortality. Successful management of AEF after esophagectomy for esophageal carcinoma has rarely been reported in the literature.
    METHODS: Here we present a rare case of a 44-year-old female with complications of AEF after esophagectomy for esophageal carcinoma, mainly presented as vomiting of blood. Both computed tomographic and computed tomography angiography of the chest showed bilateral pleural effusion and atelectasis, while gastroscopy showed large gastrointestinal bleeding. Emergency surgery was performed that included the removal of the mediastinal abscess, left lower pulmonary wedge resection, and thoracic endovascular aortic repair (TEVAR), followed by supportive treatment. The surgery went successful, and the patient was followed up for 1 year after discharge and showed good recovery. We also reviewed previous literature on the history, causes, pathophysiology, clinical presentation, diagnosis, and treatment of AEF after esophagectomy for esophageal adenocarcinoma.
    CONCLUSIONS: In our case, thoracotomy combined with TEVAR was effective in treating AEF after esophagectomy for esophageal adenocarcinoma. This case provides successful experiences for clinical diagnosis and treatment of AEF after esophagectomy for esophageal carcinoma.
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  • 文章类型: Journal Article
    食管癌(EC)引起的主动脉食管瘘(AEF)是一种威胁生命的疾病,其特征是突然出血,这往往会导致猝死。评价胸主动脉腔内修复术(TEVAR)治疗EC所致AEF的疗效和安全性。我们进行了系统评价和荟萃分析.我们搜索了MEDLINE(PubMed)数据库,Cochrane图书馆的数据库,Ichushi-Web(日本医学抽象学会的数据库),和CiNii(日本国家信息研究所的学术信息搜索服务),从2000年1月至2023年11月,提供有关TEVAR治疗急诊主动脉出血(抢救TEVAR[S-TEVAR])的文章,和预防程序(P-TEVAR)。六项研究(140例)符合荟萃分析的条件。S-TEVAR和P-TEVAR的90天死亡率为40%(95%CI23-60,I2=36%)和8%(95%CI3-17,I2=0%),分别。S-TEVAR后出血和感染并发症分别为17%(95%CI3-57,I2=71%)和20%(95%CI5-57,I2=66%),分别。P-TEVAR后出血和感染并发症分别为2%(95%CI0-10,I2=0%)和3%(95%CI1-12,I2=0%),分别。TEVAR治疗因EC引起的AEF可能是管理或预防出血性肿瘤紧急情况的有用治疗选择。
    Aorto-esophageal fistula (AEF) due to esophageal cancer (EC) is a life-threatening condition characterized by sudden hemorrhage, which often causes sudden death. To evaluate the efficacy and safety of thoracic endovascular aortic repair (TEVAR) for AEF due to EC, we performed a systematic review and meta-analysis. We searched the MEDLINE (PubMed) databases, the Cochrane Library databases, Ichushi-Web (the databases of the Japan Medical Abstract Society), and CiNii (Academic information search service of the National Institute of Information from Japan) from January 2000 to November 2023 for articles about TEVAR for an emergent aortic hemorrhage (salvage TEVAR [S-TEVAR]), and the prophylactic procedure (P-TEVAR). Six studies (140 cases) were eligible for meta-analysis. The 90-day mortality of S-TEVAR and P-TEVAR was 40% (95% CI 23-60, I2 = 36%) and 8% (95% CI 3-17, I2 = 0%), respectively. Post-S-TEVAR hemorrhagic and infectious complications were 17% (95% CI 3-57, I2 = 71%) and 20% (95% CI 5-57, I2 = 66%), respectively. Post-P-TEVAR hemorrhagic and infectious complications were 2% (95% CI 0-10, I2 = 0%) and 3% (95% CI 1-12, I2 = 0%), respectively. TEVAR for AEF due to EC may be a useful therapeutic option to manage or prevent hemorrhagic oncological emergencies.
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  • 文章类型: Journal Article
    目的:气管无名动脉瘘(TIF)是气管造口术的一种罕见但致命的并发症。总结了文献中的气管无名性动脉瘘病例,以了解死亡率的相关性。
    方法:在MEDLINE中搜索报告气管造口术后TIF患者个体特征的研究,排除没有气管造口术或在气管造口术部位进行额外手术的病例。本研究遵循PRISMA指南。
    结果:共纳入18例系列TIF患者121例和46例报告。中位年龄为40岁,52.9%为男性。总死亡率为64.5%。最初有前哨出血的病例与没有前哨出血的病例之间的死亡率存在差异(比值比[OR].34;CI[置信区间].16-.73;P=.006)。在复苏期间气管切开袖带是否过度膨胀以进行临时止血,死亡率也有所不同(OR3.57(CI1.57-8.09);P=.002)。与未治疗相比,治疗的死亡率较低(OR.11(CI0.04-.32);P<.001);如果血管内治疗与开放手术治疗没有差异。
    结论:在检测到TIF后,死亡率是一个主要问题,并且必须进行血管内或开放手术干预进行复苏。快速调查前哨出血和干预出血与临时袖带超过充气可能导致改善的结果。
    OBJECTIVE: Tracheoinnominate artery fistulas (TIFs) are a rare but deadly complication of tracheostomy. Tracheoinnominate artery fistula cases in the literature were summarized in order to understand mortality associations.
    METHODS: MEDLINE was searched for studies reporting individual characteristics of patients with TIFs after tracheostomy, excluding cases without tracheostomy or with additional procedures at the tracheostomy site. This study followed PRISMA guidelines.
    RESULTS: 121 TIF patients from 18 case series and 46 case reports were included. The median age was 40 years, and 52.9% were male. The overall mortality rate was 64.5%. There were differences in mortality between cases that presented initially with vs without sentinel bleeding (odds ratio [OR] .34; CI [confidence interval] .16-.73; P = .006). The mortality rate also differed in whether or not the tracheostomy cuff was over-inflated for temporary hemostasis during resuscitation (OR 3.57 (CI 1.57-8.09); P = .002). Treatment compared to no treatment had lower mortality rates (OR .11 (CI 0.04-.32); P < .001); no differences were found if treatment was endovascular vs open surgical.
    CONCLUSIONS: Mortality is a major concern after detection of a TIF and resuscitation paired with endovascular or open surgical intervention is imperative. Rapidly investigating sentinel bleeds and intervening upon hemorrhage with temporary cuff over inflation may lead to improved outcomes.
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  • 文章类型: Review
    目的:输尿管小动脉结石(AUF)是一种罕见但可能危及生命的疾病。这项研究的目的是回顾文献,以建立对这种病理的早期有效诊断和治疗有用的流程图。
    方法:在PubMed进行了文献检索。此外,检索到的文章进行了交叉引用。数据参数包括肿瘤学,血管和泌尿科病史,诊断,治疗,随访由2名独立评审员使用标准模板收集。
    结果:在审查时,文献中的172例AUF中共有140例,被考虑。所有患者均表现为肉眼血尿。慢性留置输尿管导管(CIUC);盆腔手术史(HPS)和盆腔放疗史(HRT)分别占81%,样品的62.1%和58.6%。AUF最主要的位置是髂总动脉输尿管交叉处。具有挑衅性措施的血管造影术具有最高的诊断敏感性(50%),并且在血管内进行支架移植物放置是当前最先进的治疗选择。
    结论:诊断失败可能会推迟潜在的挽救生命的靶向治疗并导致并发症。Trifecta血尿的识别fi阳离子,盆腔手术史(HPS)和盆腔放疗史(HPR)将允许在AUF高风险患者的身份,谁可能受益于更敏感的早期诊断调查,如CT血管造影和挑衅性血管造影。迄今为止,在AUF的情况下,选择的治疗方法包括血管内假体放置。
    Arterio-ureteralfistula (AUF) is an infrequent but potentially life-threatening condition. The aim of this study was reviewing the literature to build a flow-chart useful for an early and effective diagnosis and treatment of this pathology.
    A literature search in PubMed was conducted. In addition, retrieved articles were cross-referenced. Data parameters included oncologic, vascular and urological history, diagnostics, treatment, and follow up were collected using a standard template by 2 independent reviewers.
    A total of 140 cases of AUF out of 172 available in the literature at the time of the review, were considered. All patients presented gross hematuria. Chronic indwelling ureteral catheter (CIUC); history of pelvic surgery (HPS) and history of pelvic radiotherapy (HRT) were present respectively in 81%, 62.1%and 58.6% of the sample. The most predominant location of AUF was at the common iliac artery ureteral crossing. Angiography with provocative measures had the highest diagnostic sensitivity (50%) and endovascular treatment with stent-graft placement across the fistula is the current state of the art treatment choice.
    Failure to diagnose can postpone a potentially life-saving targeted therapy and lead to complications. The identifi-cation of the Trifecta hematuria, history of pelvic surgery (HPS) and history of pelvic radiotherapy (HPR) would allow the identity-fication of patients at high risk of AUF, who may benefit from more sensitive early diagnostic investigations such as CT angiography and provocative angiography. The treatment of choice in case of AUF to date consist in endovascular prosthesis placement.
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  • 文章类型: Case Reports
    背景:输尿管瘘(AUF)是一种罕见的,危及生命的状况,其中输尿管和普通输尿管之间发生通信,内部,或者髂外动脉.临床常用影像学检查对AUF的敏感性较低,这导致延迟诊断和增加死亡率。此外,输尿管支架使用的增加导致AUF的频率增加.
    方法:我们的两名患者分别为74岁和65岁的男性。他们都有膀胱癌病史,并接受了根治性膀胱切除术并进行了输尿管切除术。患者在1年以上的膀胱切除术中进行了常规导管更换,随后经历了间歇性总体搏动性血尿。在一系列影像学检查未能确定原因后,患者最终诊断为AUF,并接受介入放射治疗,其次是广谱抗生素。发现了积极的效果。
    结论:有相关危险因素的患者,AUF的发生率随着生存期的延长而增加。本病例报告旨在强调AUF的早期诊断和治疗,以降低死亡率。
    BACKGROUND: Arterioureteral fistula (AUF) is a rare, life-threatening condition wherein communication occurs between a ureter and the common, internal, or external iliac artery. The sensitivity of common clinical imaging examination for AUF is low, which leads to a delayed diagnosis and increased mortality. In addition, the increased use of ureteral stents contributes to the growing frequency of AUF.
    METHODS: Our two patients were 74 and 65 years old males respectively. They both had a medical history of bladder cancer and underwent radical cystectomy with ureterocutaneostomy. The patients underwent routine catheter exchange during over 1 year postradical cystectomy and subsequently experienced intermittent gross pulsatile haematuria. After a series of imaging examinations failed to identify the cause, the patients were ultimately diagnosed with AUF and treated with interventional radiotherapy, followed by broad-spectrum antibiotics. Positive effects were found.
    CONCLUSIONS: The incidence of AUF is increased with the prolongation of survival in patients with related risk factors. This case report aims to highlight early diagnosis and management of AUF to lower the mortality.
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  • 文章类型: Systematic Review
    输尿管动脉瘘(UAF)是致命的疾病。然而,由于UAF的罕见性,目前尚未就其诊断和治疗达成共识.我们报告的目的是提出一个实际的UAF病例,并系统地审查症状,危险因素,诊断,和治疗这种情况。
    该案例研究的对象是一名52岁的女性,她在尿道支架置换术期间经历了大出血。对于UAF研究的系统回顾,在PubMed上使用关键字“输尿管动脉瘘,动脉-输尿管瘘,“和”血尿。“
    我们纳入了121项研究,涉及235名患者(平均年龄,66.0岁;139名女性[59.1%])。UAF最常见于髂总动脉(n=112;47.7%)。几乎所有患者(n=232;98.7%)都有血尿。UAF的危险因素是骨盆手术(n=205;87.2%),长期使用泌尿系统支架(n=170;72.3%),肿瘤放疗(n=107;45.5%),和恶性肿瘤(n=159;67.7%)。虽然计算机断层扫描可以检测各种有用的发现,如外渗,假性动脉瘤,肾积水,输尿管浑浊,它仅对三分之一的病例在诊断上有用。在187例接受血管造影的患者(79.6%)中,有124例(66.3%)的血管造影可用于诊断UAF。关于治疗,近年来,血管内途径已被广泛使用,因为它们的侵袭性小于开放手术修复。在血管内治疗的时代,开放性手术修复的适应症包括输尿管肠瘘,脓肿形成,血管内治疗后的移植物感染。
    对于有UAF危险因素的患者,可推荐使用计算机断层扫描作为首次检查。随后,应该考虑血管造影,因为UAF可以在诊断性血管造影后使用血管内方法进行治疗.UAF的诊断和治疗通常很困难;因此,诊断的重要第一步是怀疑UAF的发生并采用多学科方法.
    Ureteroarterial fistula (UAF) is lethal condition. However, no consensus has been reached regarding the diagnosis and treatment of UAF owing to its rarity. The aim of our report was to present an actual case of UAF and systematically review the symptoms, risk factors, diagnosis, and treatment of this condition.
    The case study was of a 52-year-old woman who had experienced a massive hemorrhage during urinary stent replacement. For the systematic review of studies of UAF, those written in English and reported from 1939 to 2020 were searched for on PubMed using the keywords \"uretero-arterial fistula,\" \"arterio-ureteral fistula,\" and \"hematuria.\"
    We included 121 studies with 235 patients (mean age, 66.0 years; 139 women [59.1%]) in our review. UAF had occurred most frequently in the common iliac artery (n = 112; 47.7%). Almost all patients (n = 232; 98.7%) had complained of hematuria. The risk factors for UAF were pelvic surgery (n = 205; 87.2%), the long-term use of urinary stents (n = 170; 72.3%), oncologic radiotherapy (n = 107; 45.5%), and malignancy (n = 159; 67.7%). Although computed tomography can detect various useful findings such as extravasation, pseudoaneurysm, hydronephrosis, and opacification of ureters, it was diagnostically useful for only one third of the cases. Angiography was useful for the diagnoses of UAF for 124 (66.3%) of the 187 patients (79.6%) who had undergone angiography. With regard to treatment, endovascular approaches have been widely used in recent years because their invasiveness is lesser than that of open surgical repair. In the era of endovascular therapy, the indications for open surgical repair include ureteral-intestinal fistula, abscess formation, and graft infection after endovascular therapy.
    Computed tomography can be recommended as the first examination for patients with risk factors for UAF because of its usefulness. Subsequently, angiography should be considered because UAF can be treated using an endovascular approach after diagnostic angiography. The diagnosis and treatment of UAF can often be difficult; therefore, the important first step of diagnosis is suspecting the occurrence of UAF and using a multidisciplinary approach.
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  • 文章类型: Journal Article
    主动脉动脉瘘(ACF)是一种不常见的实体,定义为主动脉和心腔之间的异常连通。最常见的原因包括Valsalva动脉瘤窦破裂,感染性心内膜炎,外伤,主动脉夹层,或者很少是医源性的。虽然较小的通信最初可能是无症状的,这些连接的自然过程通常是难治性心力衰竭,因为它们不会自发愈合。较大的瘘管可能会危及生命,死亡率很高,因此,一旦认识到,手术通常被认为是治疗的选择。诊断,然而,可能是具有挑战性的,和各种成像模式通常用于诊断。这篇综述强调了常见的潜在病因,临床表现,以及ACF对这种罕见的每个心腔的放射学成像表现,但是临床上重要的实体,重点是CT。
    Aorto-cameral fistula (ACF) is an uncommon entity, defined as an abnormal communication between the aorta and a cardiac chamber. The most common causes include ruptured sinus of Valsalva aneurysm, infective endocarditis, traumatic injury, aortic dissection, or rarely can be iatrogenic in nature. While smaller communications may initially be asymptomatic, the natural course of these connections is generally refractory heart failure as they do not spontaneously heal. Larger fistulas can be life threatening with high mortality rates, and therefore once recognized, surgery is generally considered the treatment of choice. Diagnosis, however, can be challenging, and various imaging modalities are often used for diagnosis. This review highlights common underlying etiologies, clinical manifestations, and radiologic imaging appearances of ACF to each of the cardiac chambers of this uncommon, but clinically important entity, with emphasis on CT.
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  • 文章类型: Case Reports
    右冠状动脉左心室(RCA-LV)瘘伴有巨大的右冠状动脉动脉瘤(CAA)是一种极为罕见的心脏病。该病例研究提供了一个大左心室(LV)和巨大右CAA的患者,其最大内径约为56.6mm,与左心室连通的内径约为22mm。病人接受了手术治疗,涉及CAA近端缝合和冠状动脉旁路移植术(CABG)。RCA-LV瘘伴巨大右CAA可能涉及严重并发症,如血栓形成,破裂,和心力衰竭。因此,有必要针对这种情况建立有效的管理策略。虽然这种情况不是唯一的,它作为一个典型的手术治疗方法的实施例子。
    Right coronary artery-left ventricular (RCA-LV) fistula with associated giant right coronary artery aneurysm (CAA) is an extremely rare cardiac condition. This case study presents a patient with a large left ventricle (LV) and a giant right CAA with a maximal inner diameter of approximately 56.6 mm and an inner diameter of approximately 22 mm at its communication with the left ventricle. The patient underwent surgical management, involving suturing of the proximal end of the CAA and coronary artery bypass grafting (CABG). RCA-LV fistula with a giant right CAA may involve serious complications, such as thrombosis, rupture, and heart failure. Therefore, it is necessary to establish effective management strategies for this condition. Although this case is not unique, it serves as an illustrative example of the implementation of a classic surgical treatment method.
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