心血管压力反射敏感性(cvBRS)反映了响应收缩压变化调节心率的效率。国际指南建议老年人每周至少进行150分钟的中等强度体力活动。我们检验了这样的假设,即达到这些指南的老年人将表现出较高的心迷走压力反射敏感性。
老年人的横断面比较(活跃,66±5年,251±79分钟/周;n=19),谁没有(不活动,68±7年,89±32分钟/周;n=17)符合活动指南。记录逐次搏动R-R间隔(心电图)和收缩压(手指光电容积描记术)。使用序列技术从10分钟的静息仰卧位数据中评估自发性心肌压力反射敏感性。在Valsalva动作的早期II期和IV期也测量了心肌压力反射功能。在最大周期测功期间确定峰值摄氧量。使用PiezoRx和activPAL评估了5天以上的中等强度体力活动和久坐时间,分别。
组的峰值摄氧量相似(活性25±9与非活动22±6ml/kg/min;p=0.218)和久坐时间(活动529±60vs.不活动568±88分钟/天;p=0.130)。然而,活跃的群体有更大的(所有,p<0.019)静止时cvBRS(9.1±2.7vs.5.0±1.9ms/mmHg),在第二阶段(8.2±3.8vs.5.4±2.1ms/mmHg),在IV期(9.9±3.8vs.5.6±1.6ms/mmHg)。在合并的样本中,中等强度的体力活动呈正相关(所有,p<0.015),自发(R=0.427),第二阶段(R=0.447),和IV期cvBRS(R=0.629)。
独立于有氧健身和久坐时间,在老年人中,满足活动指南与静息时和Valsalva动作期间的心迷走压力反射敏感性较高相关.
Cardiovagal baroreflex sensitivity (cvBRS) reflects the efficiency of modulating heart rate in response to changes in systolic blood pressure. International
guidelines recommend that older adults achieve at least 150 min of moderate-vigorous physical activity per week. We tested the hypothesis that older adults who achieve these
guidelines will exhibit greater cardiovagal baroreflex sensitivity versus those who do not.
A cross-sectional comparison of older adults who did (active, 66 ± 5 years, 251 ± 79 min/week; n = 19) and who did not (inactive, 68 ± 7 years, 89 ± 32 min/week; n = 17) meet the activity
guidelines. Beat-by-beat R-R intervals (electrocardiography) and systolic blood pressure (finger photoplethysmography) were recorded. Spontaneous cardiovagal baroreflex sensitivity was assessed using the sequence technique from 10 min of resting supine data. Cardiovagal baroreflex function was also measured during early phase II and phase IV of the Valsalva maneuver. Peak oxygen uptake was determined during maximal cycle ergometry. Moderate-vigorous intensity physical activity and time spent sedentary were assessed over 5 days using the PiezoRx and activPAL, respectively.
Groups had similar peak oxygen uptake (active 25 ± 9 vs. inactive 22 ± 6 ml/kg/min; p = 0.218) and sedentary time (active 529 ± 60 vs. inactive 568 ± 88 min/day; p = 0.130). However, the active group had greater (all, p < 0.019) cvBRS at rest (9.1 ± 2.7 vs. 5.0 ± 1.9 ms/mmHg), during phase II (8.2 ± 3.8 vs. 5.4 ± 2.1 ms/mmHg), and during phase IV (9.9 ± 3.8 vs. 5.6 ± 1.6 ms/mmHg). In the pooled sample, moderate-vigorous physical activity was positively correlated (all, p < 0.015) with spontaneous (R = 0.427), phase II (R = 0.447), and phase IV cvBRS (R = 0.629).
Independent of aerobic fitness and sedentary time, meeting activity
guidelines was associated with superior cardiovagal baroreflex sensitivity at rest and during the Valsalva maneuver in older adults.