最常见的染色体综合征,如唐氏,帕托,爱德华兹,特纳,威廉姆斯以各种方式影响儿科人群,先天性心脏病解释了他们生活质量的改变。缺乏对这些综合征的心脏异常进行回顾的研究,存在的是过去几十年的出版物。我们审查了MEDLINE等数据库,LILACS,SCIELO,和谷歌学者,选择最好的证据,每个染色体综合征都与先天性心脏病有关,组成五个搜索小组。这篇文章显示了综述的研究中描述的每种心脏病的特征,作者,发布日期,国家,和人口研究,以及对疾病发生频率和死亡率的简要描述。这篇综述中描述的结果与以前的现有文献进行了对比,以验证报告的频率之间是否存在对应关系。最常见的先天性心脏病是房室间隔缺损(AVSD)。室间隔缺损(VSD),房间隔缺损(ASD),唐氏综合征患者的持续性动脉导管(PDA),PDA,ASD,Patau综合征患者的室间隔缺损,AVSD,爱德华兹综合征的PDA和瓣膜缺损,二叶主动脉瓣,特纳综合征的主动脉缩窄和主动脉瓣狭窄,Williams综合征的主动脉瓣上狭窄和肺动脉狭窄。
Most frequent chromosomal syndromes like Down, Patau, Edwards, Turner, and Williams affect the pediatric population in various ways, and congenital heart disease explains the altered quality of life they suffer. There is a lack of studies reviewing the cardiac anomalies in these syndromes, and the ones that exist are publications from past decades. We reviewed databases such as MEDLINE, LILACS, SCIELO, and Google Scholar, selecting the best possible evidence, and each chromosomal syndrome was investigated in relation to congenital heart disease, constituting five search groups. The article shows the characteristics of each heart disease described in the studies reviewed, the author, date of publication, country, and population studied, as well as a brief description of the frequency of the disease and its mortality. The results described in this
review were contrasted with previous existing literature to verify if there was correspondence between the reported frequencies. The most frequent congenital heart diseases were atrioventricular septal defect (AVSD), ventricular septal defect (VSD), atrial septal defect (ASD), and persistent ductus arteriosus (PDA) in Down syndrome patients, PDA, ASD, and VSD in Patau syndrome patients, AVSD, PDA and valvular defects in Edwards syndrome, bicuspid aortic valve, aortic coarctation and aortic stenosis in Turner syndrome, and supravalvular aortic stenosis and pulmonary stenosis in Williams syndrome.