多胎妊娠与重要的产妇有关,胎儿,和新生儿风险,包括早产,低出生体重,先兆子痫,贫血,产后出血,宫内生长受限,新生儿发病率,新生儿和婴儿死亡率上升。辅助生殖技术(ART)治疗应优先考虑减少此类事件的努力,抵制患者在每次移植时移植多个胚胎的需求,以提高成功率。扩展文化,胚胎选择,单囊胚移植可以降低高阶多胎妊娠的风险。有趣的是,选择性单胚胎移植(eSET)大大减少,但并不能完全消除,多重妊娠的可能性。单卵孪生(MZT)的发生导致同卵双胞胎。与自然受孕相比,在接受体外受精(IVF)的女性中更为普遍。事实上,据报道,体外受精和自然受孕中单卵双胞胎的风险分别为1.7%和0.4%,分别。在IVF中可能增加MZT风险的因素是多胚胎移植,显微操作,和扩展的体外培养。确定绒毛膜和羊膜性对于评估妊娠早期超声检查中的多胎妊娠至关重要。受精后3天内胚胎分裂导致双生子,而单绒毛膜双胞胎发生在受精后4到8天之间分裂时。通过在自然怀孕中进行的观察来建议这些时间。在艺术中,有单胚胎移植(SET)的二胎双胞胎的证据.这里,我们报告了一例在我们中心发生单个胚泡移植后的二胎性羊膜三胞胎。据我们所知,这是迄今为止记录的第一个案例。
Multiple pregnancies are associated with significant maternal, fetal, and neonatal risks, including prematurity, low birth weight, pre-eclampsia, anemia, postpartum hemorrhage, intrauterine growth restriction, neonatal morbidity, and increased neonatal and infant mortality rates. Assisted reproductive technology (ART) treatments should prioritize efforts to reduce such events, resisting patient demand for the transfer of multiple embryos at each transfer to increase success rates. Extended culture, embryo selection, and single blastocyst transfer can mitigate the risk of high-order multiple pregnancies. Intriguingly, elective single-embryo transfer (eSET) greatly reduces, but does not completely eliminate, the likelihood of multiple gestations. The occurrence of monozygotic twinning (MZT) gives rise to identical twins. It is more prevalent in women undergoing in vitro fertilization (IVF) compared with natural conception. In fact, the reported risks of monozygotic twinning in IVF and natural conception are 1.7 and 0.4%, respectively. The factors suspected to increase the risk of MZT in IVF are multiple embryo transfer, micromanipulation, and extended in vitro culture. Determining chorionicity and amnionicity is crucial in the assessment of multiple pregnancies during the first-trimester ultrasound examination. Dichorionic twins result from embryo splitting within 3 days after fertilization, while monochorionic twins occur when the splitting takes place between 4 and 8 days after fertilization. These timings are suggested by observations carried out in natural pregnancies. In ART, there is evidence of dichorionic twins derived from single embryo transfer (SET). Here, we report a
case of dichorionic diamniotic
triplets after a single blastocyst transfer occurred in our center. To our knowledge, this is the first
case documented so far.