创伤性脑损伤(TBI)是由大脑周围骨结构和相关组织的身体或创伤性损伤引起的,会导致各种后遗症,包括简单的脑震荡,急性硬膜外血肿,实质挫伤,蛛网膜下腔出血,弥漫性轴索损伤,慢性创伤性脑病.磁敏感加权成像(SWI)提高了神经成像对这些损伤的准确性。SWI基于3D梯度回波磁共振成像(MRI),具有长回波时间和流量补偿。由于它对脱氧血红蛋白的敏感性,含铁血黄素,铁,还有钙,SWI是非常丰富的信息和优于常规的MRI诊断和随访的患者,急性,亚急性,和长时间的出血。本系统综述旨在评估和总结已发表的报告SWI结果的文章,以评估TBI,并确定临床状态与SWI结果之间的相关性。因此,我们的分析还旨在确定用于评估TBI患者的合适MRI序列.我们在Medline和Embase在线电子数据库中搜索了2012年以来发表的相关论文。我们发现,SWI在检测和表征TBI中的微出血方面比梯度回波MRI具有更高的灵敏度,并且能够区分抗磁性钙化和顺磁性微出血。然而,重要的是,未来的研究不仅要继续评估SWI在TBI中的实用性,还要尝试克服这篇综述中描述的研究的局限性,这应该有助于验证我们分析的结论和建议。
Traumatic brain injury (TBI) results from physical or traumatic injuries to the brain\'s surrounding bony structures and associated tissues, which can lead to various sequelae, including simple concussion, acute epidural hematoma, parenchymal contusions, subarachnoid hemorrhage, diffuse axonal injury, and chronic traumatic encephalopathy. Susceptibility-weighted imaging (SWI) has enhanced the accuracy of neuroimaging for these injuries. SWI is based on 3D gradient echo magnetic resonance imaging (MRI) with long echo times and flow compensation. Owing to its sensitivity to deoxyhemoglobin, hemosiderin, iron, and calcium, SWI is extremely informative and superior to conventional MRI for the diagnosis and follow-up of patients with acute, subacute, and prolonged hemorrhage. This systematic
review aimed to evaluate and summarize the published articles that report SWI results for the evaluation of TBI and to determine correlations between clinical status and SWI results. Consequently, our analysis also aimed to identify the appropriate MRI sequences to use in the assessment of patients with TBI. We searched the Medline and Embase online electronic databases for relevant papers published from 2012 onwards. We found that SWI had higher sensitivity than gradient echo MRI in detecting and characterizing microbleeds in TBIs and was able to differentiate diamagnetic calcifications from paramagnetic microhemorrhages. However, it is important that future research not only continues to evaluate the utility of SWI in TBIs but also attempts to overcome the limitations of the studies described in this
review, which should help validate the conclusions and recommendations from our analysis.